Search Results - "Berlo, Suzanne"
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IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis
Published in PloS one (14-01-2009)“…The anti-inflammatory capacity of heat shock proteins (HSP) has been demonstrated in various animal models of inflammatory diseases and in patients. However,…”
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Journal Article -
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The Human Endoplasmic Reticulum Molecular Chaperone BiP Is an Autoantigen for Rheumatoid Arthritis and Prevents the Induction of Experimental Arthritis
Published in The Journal of immunology (1950) (01-02-2001)“…Rheumatoid arthritis (RA) is the most common, crippling human autoimmune disease. Using Western blotting and tandem mass spectroscopy, we have identified the…”
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Journal Article -
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Autoantigen-Specific IL-10-Transduced T Cells Suppress Chronic Arthritis by Promoting the Endogenous Regulatory IL-10 Response
Published in The Journal of immunology (1950) (01-02-2008)“…Deficient T cell regulation can be mechanistically associated with development of chronic autoimmune diseases. Therefore, combining the regulatory properties…”
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Journal Article -
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Cartilage proteoglycan-specific T cells as vectors of immunomodulatory biologicals in chronic proteoglycan-induced arthritis
Published in Molecular immunology (01-08-2008)“…Systemic administration of agents that neutralize or antagonize T h1-mediated pro-inflammatory responses has been demonstrated to ameliorate inflammation in…”
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Naive transgenic T cells expressing cartilage proteoglycan-specific TCR induce arthritis upon in vivo activation
Published in Journal of autoimmunity (01-11-2005)“…Proteoglycan (PG)-induced arthritis (PGIA), a murine model for rheumatoid arthritis (RA), is driven by antigen (PG)-specific T and B cell activation. In order…”
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Journal Article Conference Proceeding -
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Achievement of a synergistic adjuvant effect on arthritis induction by activation of innate immunity and forcing the immune response toward the Th1 phenotype
Published in Arthritis and rheumatism (01-05-2004)“…Objective To apply and analyze the mechanisms of action of dimethyldioctadecylammonium bromide (DDA), a powerful adjuvant that does not have the side effects…”
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Increased arthritis susceptibility in cartilage proteoglycan–specific T cell receptor–transgenic mice
Published in Arthritis and rheumatism (01-08-2006)“…Objective To better understand the role of antigen (arthritogenic epitope)–specific T cells in the development of autoimmune arthritis. Methods A transgenic…”
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Journal Article -
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Induction of arthritis in SCID mice by T cells specific for the “shared epitope” sequence in the G3 domain of human cartilage proteoglycan
Published in Arthritis and rheumatism (01-10-2003)“…Objective To study the immunologic function and determine the fine epitope structure of a synthetic peptide p135H (2373TTYKRRLQKRSSRHP) of the G3 domain of…”
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Stress Proteins as Inducers and Targets of Regulatory T Cells in Arthritis
Published in International reviews of immunology (01-05-2005)“…Immunization with microbial or mammalian stress proteins or heat-shock proteins in models of experimental autoimmunity has been observed to lead to increased…”
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SINGLE INJECTION OF MESENCHYMAL STEM CELLS DECREASES PROGRESSION OF PROTEOGLYCAN-INDUCED ARTHRITIS
Published in Turkish journal of pediatrics (01-01-2008)Get full text
Journal Article -
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Human Monoclonal Antibodies Isolated from Type I Diabetes Patients Define Multiple Epitopes in the Protein Tyrosine Phosphatase-Like IA-2 Antigen
Published in The Journal of immunology (1950) (15-10-2000)“…Protein tyrosine phosphatase-like IA-2 autoantigen is one of the major targets of humoral autoimmunity in patients with insulin-dependant diabetes mellitus…”
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