Search Results - "Berkich, D."

Energy sources for glutamate neurotransmission in the retina: absence of the aspartate/glutamate carrier produces reliance on glycolysis in glia by Xu, Y., Ola, M. S., Berkich, D. A., Gardner, T. W., Barber, A. J., Palmieri, F., Hutson, S. M., LaNoue, K. F.

“…The mitochondrial transporter, the aspartate/glutamate carrier (AGC), is a necessary component of the malate/aspartate cycle, which promotes the transfer into…”
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Mitochondrial transport proteins of the brain by Berkich, D.A., Ola, M.S., Cole, J., Sweatt, A.J., Hutson, S.M., LaNoue, K.F.

“…In this study, cellular distribution and activity of glutamate and γ‐aminobutyric acid (GABA) transport as well as oxoglutarate transport across brain…”
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Whole‐brain glutamate metabolism evaluated by steady‐state kinetics using a double‐isotope procedure: effects of gabapentin by Xu, Y., Öz, G., LaNoue, K. F., Keiger, C. J., Berkich, D. A., Gruetter, R., Hutson, S. H.

“…Cerebral rates of anaplerosis are known to be significant, yet the rates measured in vivo have been debated. In order to track glutamate metabolism in brain…”
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Role of Branched‐Chain Aminotransferase Isoenzymes and Gabapentin in Neurotransmitter Metabolism by Hutson, S. M., Berkich, D., Drown, P., Xu, Baiyang, Aschner, Michael, LaNoue, Kathryn F.

“…: Because it is well known that excess branched‐chain amino acids (BCAAs) have a profound influence on neurological function, studies were conducted to…”
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Role of Pyruvate Carboxylase in Facilitation of Synthesis of Glutamate and Glutamine in Cultured Astrocytes by Gamberino, William C., Berkich, Deborah A., Lynch, Christopher J., Xu, Baiyang, LaNoue, Kathryn F.

“…: CO2 fixation was measured in cultured astrocytes isolated from neonatal rat brain to test the hypothesis that the activity of pyruvate carboxylase influences…”
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Nitrogen shuttling between neurons and glial cells during glutamate synthesis by Lieth, Erich, LaNoue, Kathryn F., Berkich, Deborah A., Xu, Baiyang, Ratz, Michael, Taylor, Charles, Hutson, Susan M.

“…The relationship between neuronal glutamate turnover, the glutamate/glutamine cycle and de novo glutamate synthesis was examined using two different model…”
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Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina by LaNoue, Kathyrn F., Berkich, Deborah A., Conway, Myra, Barber, Alistair J., Hu, Lain-Yen, Taylor, Charles, Hutson, Susan

“…In this study aminotransferase inhibitors were used to determine the relative importance of different aminotransferases in providing nitrogen for de novo…”
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Evidence for regulated coupling of A1 adenosine receptors by phosphorylation in Zucker rats by Berkich, D A, Luthin, D R, Woodard, R L, Vannucci, S J, Linden, J, LaNoue, K F

“…Studies were designed to find the molecular basis for previous observations that lipolysis is less active and A1 adenosine receptor signaling is more active in…”
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Effects of adenosine receptor antagonism on protein tyrosine phosphatase in rat skeletal muscle by Crist, George H, Xu, Baiyang, Berkich, Deborah A, LaNoue, Kathryn F

“…Earlier studies have shown that whole body adenosine receptor antagonism increases skeletal muscle insulin sensitivity in insulin-resistant Zucker rats. To…”
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Rates of various reactions catalyzed by ATP synthase as related to the mechanism of ATP synthesis by Berkich, D A, Williams, G D, Masiakos, P T, Smith, M B, Boyer, P D, LaNoue, K F

“…The forward and reverse rates of the overall reaction catalyzed by the ATP synthase in intact rat heart mitochondria, as measured with 32P, were compared with…”
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Rate-limiting step and control of coenzyme A synthesis in cardiac muscle by Robishaw, J D, Berkich, D, Neely, J R

“…Control of coenzyme A synthesis was studied in isolated, perfused rat hearts. Pantothenic acid (PA), coenzyme A, and intermediates in the the pathway were…”
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Regulation of coenzyme A synthesis in heart muscle: effects of diabetes and fasting by Reibel, D.K, Wyse, B.W, Berkich, D.A, Neely, J.R

“…Regulation of coenzyme A (CoA) synthesis was studied in the isolated perfused rat heart. Incorporation of [14C]pantothenic acid ([14C]PA) into CoA was…”
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Effects of diabetes and fasting on pantothenic acid metabolism in rats by Reibel, D K, Wyse, B W, Berkich, D A, Palko, W M, Neely, J R

“…The effects of fasting and diabetes on pantothenic acid (PA) metabolism were studied in rats. Tissue levels of PA and coenzyme A (CoA) and rates of [14C]PA…”
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A 31P NMR study of mitochondrial inorganic phosphate visibility : effects of Ca2+, Mn2+, and the pH gradient by HUTSON, S. M, WILLIAMS, G. D, BERKICH, D. A, LANOUE, K. F, BRIGGS, R. W

“…The effects of external pH, temperature, and Ca2+ and Mn2+ concentrations on the compartmentation and NMR visibility of inorganic phosphate (Pi) were studied…”
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31P NMR saturation-transfer study of the in situ kinetics of the mitochondrial adenine nucleotide translocase by MASIAKOS, P. T, WILLIAMS, G. D, BERKICH, D. A, SMITH, M. B, LANOUE, K. F

“…The exchange of intramitochondrial ATP (ATP(in)) for extramitochondrial ATP (ATP(out)) was measured by using 31P NMR spectroscopy over a range of temperatures…”
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Coenzyme A metabolism in pantothenic acid-deficient rats by Reibel, D K, Wyse, B W, Berkich, D A, Neely, J R

“…The pantothenic acid (PA) and coenzyme A (CoA) content of various organs of rats maintained on a PA-deficient diet were determined. The PA content of heart,…”
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Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists by Jacobson, Kenneth A, Nikodijevic, Olga, Ji, Xiao Duo, Berkich, Deborah A, Eveleth, David, Dean, Reginald L, Hiramatsu, Kenichiro, Kassell, Neal F, Van Galen, Philip J. M

“…A series of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine was synthesized, revealing that N6-(p-sulfophenyl)adenosine (10b) is a…”
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Neuroglial Metabolism in the Awake Rat Brain: CO2 Fixation Increases with Brain Activity by Oz, Gulin, Berkich, Deborah A, Henry, Pierre-Gilles, Xu, Yuping, LaNoue, Kathryn, Hutson, Susan M, Gruetter, Rolf

“…Glial cells are thought to supply energy for neurotransmission by increasing nonoxidative glycolysis; however, oxidative metabolism in glia may also contribute…”
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Metabolic influence of gabapentin in brain by LaNoue, K. F., Kreiger, J., Xu, Y., Wood, M., Berkich, D. A., Hutson, S. M.

“…De novo synthesis of glutamate in excised rat retinas results in incorporation of 14 CO 2 into neuronal glutamate that is partially (30%) inhibited by the…”
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A1 adenosine receptor antagonism improves glucose tolerance in Zucker rats by Xu, B, Berkich, D.A, Crist, G.H, LaNoue, K.F

“…The A1 adenosine receptor (A1ar) antagonist 1,3-dipropyl-8-(p-acrylic)-phenylxanthine (BW-1433) was administered to lean and obese Zucker rats to probe the…”
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