Search Results - "Berkebile, Zachary W."
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CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infections
Published in PLoS pathogens (01-11-2024)“…Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus and the leading cause of infectious disease related birth defects worldwide. How the immune response…”
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The Placental Response to Guinea Pig Cytomegalovirus Depends Upon the Timing of Maternal Infection
Published in Frontiers in immunology (15-06-2021)“…Human cytomegalovirus (HCMV) infects the placenta, and these placental infections can cause fetal injury and/or demise. The timing of maternal HCMV infection…”
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Journal Article -
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Human trophoblast stem cells restrict human cytomegalovirus replication
Published in Journal of virology (16-04-2024)“…Placental infection plays a central role in the pathogenesis of congenital human cytomegalovirus (HCMV) infections and is a cause of fetal growth restriction…”
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Cytomegalovirus infection elicits a conserved chemokine response from human and guinea pig amnion cells
Published in Virology (New York, N.Y.) (01-09-2020)“…Human cytomegalovirus (HCMV) infects the chorioamnion, but whether these infections cause fetal membrane dysfunction remains poorly understood. We sought to…”
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Journal Article