Search Results - "Berk, MIchael"
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1
Theory of mind in major depressive disorder: A meta-analysis
Published in Journal of affective disorders (01-02-2016)“…Abstract Objective Social cognitive deficits can contribute to risk for depression and to psychosocial impairment during depression. However, available…”
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2
The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders
Published in BMC medicine (01-04-2015)“…Mitochondrial dysfunction and defects in oxidative metabolism are a characteristic feature of many chronic illnesses not currently classified as mitochondrial…”
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3
Nutritional psychiatry: the present state of the evidence
Published in Proceedings of the Nutrition Society (01-11-2017)“…Mental illness, including depression, anxiety and bipolar disorder, accounts for a significant proportion of global disability and poses a substantial social,…”
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4
Bipolar disorder
Published in The Lancet (British edition) (09-04-2016)“…Summary Bipolar disorder is a recurrent chronic disorder characterised by fluctuations in mood state and energy. It affects more than 1% of the world's…”
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5
Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications
Published in Neuroscience and biobehavioral reviews (01-01-2015)“…Mitochondria play a critical role in regulating cellular functions including bioenergetics, calcium homeostasis, redox signalling, and apoptotic cell death…”
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N -acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action
Published in Journal of psychiatry & neuroscience (01-03-2011)“…There is an expanding field of research investigating the benefits of alternatives to current pharmacological therapies in psychiatry. N -acetylcysteine (NAC)…”
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The chemistry and biological activities of N-acetylcysteine
Published in Biochimica et biophysica acta (01-08-2013)“…N-acetylcysteine (NAC) has been in clinical practice for several decades. It has been used as a mucolytic agent and for the treatment of numerous disorders…”
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8
Guidelines for Developing and Reporting Machine Learning Predictive Models in Biomedical Research: A Multidisciplinary View
Published in Journal of medical Internet research (16-12-2016)“…As more and more researchers are turning to big data for new opportunities of biomedical discoveries, machine learning models, as the backbone of big data…”
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9
Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses
Published in BMC medicine (06-02-2015)“…The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the…”
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Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review
Published in Neuroscience and biobehavioral reviews (01-08-2015)“…N-acetylcysteine (NAC) is recognized for its role in acetaminophen overdose and as a mucolytic. Over the past decade, there has been growing evidence for the…”
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11
Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
Published in BMC medicine (29-06-2012)“…It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex…”
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Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut
Published in Journal of affective disorders (01-12-2012)“…Abstract Background Recently, we discovered that depression is accompanied by increased IgM and IgA responses directed against gram negative gut commensals…”
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13
Time for united action on depression: a Lancet–World Psychiatric Association Commission
Published in The Lancet (British edition) (05-03-2022)“…[...]depression is a heterogeneous entity experienced with various combinations of signs and symptoms, severity levels, and longitudinal trajectories…”
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14
Microparticles release by adipocytes act as "find-me" signals to promote macrophage migration
Published in PloS one (07-04-2015)“…Macrophage infiltration of adipose tissue during weight gain is a central event leading to the metabolic complications of obesity. However, what are the…”
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15
The Neuro-Immune Pathophysiology of Central and Peripheral Fatigue in Systemic Immune-Inflammatory and Neuro-Immune Diseases
Published in Molecular neurobiology (01-03-2016)“…Many patients with systemic immune-inflammatory and neuro-inflammatory disorders, including depression, rheumatoid arthritis, systemic lupus erythematosus,…”
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16
The Putative Use of Lithium in Alzheimer's Disease
Published in Current Alzheimer research (01-08-2016)“…Alzheimer`s disease is a progressive neurodegenerative illness characterized by the invariant existence of β-amyloid plaques and neurofibrillary tangles…”
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Functional Implications of the IL-23/IL-17 Immune Axis in Schizophrenia
Published in Molecular neurobiology (01-12-2017)“…The aetiology of schizophrenia seems to stem from complex interactions amongst environmental, genetic, metabolic, immunologic and oxidative components. Chronic…”
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The new field of 'precision psychiatry'
Published in BMC medicine (13-04-2017)“…Precision medicine is a new and important topic in psychiatry. Psychiatry has not yet benefited from the advanced diagnostic and therapeutic technologies that…”
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A randomised controlled trial of dietary improvement for adults with major depression (the 'SMILES' trial)
Published in BMC medicine (30-01-2017)“…The possible therapeutic impact of dietary changes on existing mental illness is largely unknown. Using a randomised controlled trial design, we aimed to…”
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Diet and depression: exploring the biological mechanisms of action
Published in Molecular psychiatry (01-01-2021)“…The field of nutritional psychiatry has generated observational and efficacy data supporting a role for healthy dietary patterns in depression onset and…”
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