Search Results - "Berk, J L"

Safety and efficacy of high-dose melphalan and auto-SCT in patients with AL amyloidosis and cardiac involvement by Girnius, S, Seldin, D C, Meier-Ewert, H K, Sloan, J M, Quillen, K, Ruberg, F L, Berk, J L, Doros, G, Sanchorawala, V

“…In Ig light chain (AL) amyloidosis, cardiac involvement is associated with worse prognosis and increased treatment-related complications. In this retrospective…”
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EMP1, a novel poor prognostic factor in pediatric leukemia regulates prednisolone resistance, cell proliferation, migration and adhesion by Ariës, I M, Jerchel, I S, van den Dungen, R E S R, van den Berk, L C J, Boer, J M, Horstmann, M A, Escherich, G, Pieters, R, den Boer, M L

“…Still 20% of pediatric acute lymphoblastic leukemia (ALL) patients relapse on or after current treatment strategies. Treatment failure is associated with…”
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High-dose intravenous melphalan and autologous stem cell transplantation as initial therapy or following two cycles of oral chemotherapy for the treatment of AL amyloidosis: results of a prospective randomized trial by SANCHORAWALA, V, WRIGHT, D. G, SKINNER, M, SELDIN, D. C, FALK, R. H, FINN, K. T, DEMBER, L. M, BERK, J. L, QUILLEN, K, ANDERSON, J. J, COMENZO, R. L

“…A prospective randomized trial was conducted to study the timing of high-dose intravenous melphalan and autologous stem cell transplantation (HDM/SCT) in AL…”
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Tandem cycles of high-dose melphalan and autologous stem cell transplantation increases the response rate in AL amyloidosis by SANCHORAWAIA, V, WRIGHT, D. G, QUIIIEN, K, FINN, K. T, DEMBER, L. M, BERK, J. L, DOROS, G, FISHER, C, SKINNER, M, SEIDIN, D. C

“…Clinical outcomes of patients with AL amyloidosis treated with high-dose melphalan and stem cell transplantation (HDM/SCT) are tightly linked to the…”
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Early data on long‐term efficacy and safety of inotersen in patients with hereditary transthyretin amyloidosis: a 2‐year update from the open‐label extension of the NEURO‐TTR trial by Brannagan, T. H., Wang, A. K., Coelho, T., Waddington Cruz, M., Polydefkis, M. J., Dyck, P. J., Plante‐Bordeneuve, V., Berk, J. L., Barroso, F., Merlini, G., Conceição, I., Hughes, S. G., Kwoh, J., Jung, S. W., Guthrie, S., Pollock, M., Benson, M. D., Gertz, M., Drachman, Brian, Gorevic, Peter, Heitner, Stephen, Scheinberg, Morton, Schmidt, Hartmut, Whelan, Carol, Adams, David, Campistol Plana, Josep Maria, Gamez, Josep, Gane, Edward, Kristen, Arnt, Obici, Laura, Salvi, Fabrizio, Souza Bulle Oliveira, Acary, Vita, Giuseppe

“…Background and purpose Hereditary transthyretin (hATTR) amyloidosis causes progressive polyneuropathy resulting from transthyretin (TTR) amyloid deposition…”
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Dose-intensive melphalan with blood stem-cell support for the treatment of AL (amyloid light-chain) amyloidosis : Survival and responses in 25 patients by COMENZO, R. L, VOSBURGH, E, O'HARA, C, ARKIN, C. F, WRIGHT, D. G, SKINNER, M, FALK, R. H, SANCHORAWALA, V, REISINGER, J, DUBREY, S, DEMBER, L. M, BERK, J. L, AKPEK, G, LAVALLEY, M

“…AL (amyloid light-chain) amyloidosis is an uncommon plasma cell disorder in which depositions of amyloid light-chain protein cause progressive organ failure…”
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Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience by Cowan, Andrew J, Skinner, Martha, Seldin, David C, Berk, John L, Lichtenstein, David R, O'Hara, Carl J, Doros, Gheorghe, Sanchorawala, Vaishali

“…Amyloidosis of the gastrointestinal tract, with biopsy-proven disease, is rare. We reviewed a series of patients who presented with biopsy-proven…”
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Retrospective study of a TTR FAP cohort to modify NIS + 7 for therapeutic trials by Suanprasert, N, Berk, J.L, Benson, M.D, Dyck, P.J.B, Klein, C.J, Gollob, J.A, Bettencourt, B.R, Karsten, V, Dyck, P.J

“…Abstract Protein stabilization and oligonucleotide therapies are being tested in transthyretin amyloid polyneuropathy (TTR FAP) trials. From retrospective…”
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Effect of dose-intensive intravenous melphalan and autologous blood stem-cell transplantation on AL amyloidosis-associated renal disease by DEMBER, Laura M, SANCHORAWALA, Vaishali, SELDIN, David C, WRIGHT, Daniel G, LAVALLEY, Michael, BERK, John L, FALK, Rodney H, SKINNER, Martha

“…Dose-intensive intravenous melphalan with autologous blood stem-cell transplantation induces remission of the plasma cell dyscrasia in a substantial proportion…”
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Intermediate‐dose intravenous melphalan and blood stem cells mobilized with sequential GM+G‐CSF or G‐CSF alone to treat AL (amyloid light chain) amyloidosis by COMENZO, RAYMOND L., SANCHORAWALA, VAISHALI, FISHER, CATHERINE, AKPEK, GORGUN, FARHAT, MAHA, CERDA, SANDRA, BERK, JOHN L., DEMBER, LAURA M., FALK, RODNEY, FINN, KATHERINE, SKINNER, MARTHA, VOSBURGH, EVAN

“…AL amyloidosis patients ineligible for dose‐intensive melphalan (200 mg/m2) were enrolled on a phase II trial to be treated with two cycles of…”
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Fevers, weight loss, and bilateral peripheral infiltrates in a young man by Lee, F E, Caracta, C F, Fine, A, Berk, J L

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Effect of okadaic acid on elastin gene expression in interstitial lung fibroblasts by Berk, J L, Massoomi, N, Krupsky, M, Goldstein, R H

“…Okadaic acid (OA), a specific serine/threonine protein phosphatase inhibitor, downregulated tropoelastin formation and elastin mRNA levels in a dose-related…”
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Tracheobronchial amyloidosis. The Boston University experience from 1984 to 1999 by O'Regan, A, Fenlon, H M, Beamis, Jr, J F, Steele, M P, Skinner, M, Berk, J L

“…Tracheobronchial amyloidosis (TBA), an idiopathic disorder characterized by deposition of fibrillar proteins in the tracheobronchial tree, occurred in 10…”
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Recombinant interleukin-1 beta inhibits elastin formation by a neonatal rat lung fibroblast subtype by Berk, J L, Franzblau, C, Goldstein, R H

“…The effect of recombinant interleukin-1 beta (rIL-1 beta) on elastin accumulation by lipid-laden interstitial cells (LIC) derived from neonatal rat lung was…”
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The effect of retinoic acid on amino acid uptake and protein synthesis by lung fibroblasts by KRUPSKY, M, FINE, A, BERK, J. L, GOLDSTEIN, R. H

“…The effect of retinoic acid (RA) on the uptake and utilization of extracellular amino acids by fetal lung fibroblasts was examined. RA decreased the…”
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The diflunisal trial: update on study drug tolerance and disease progression by Berk, J. L., Dyck, P. J., Obici, L., Zeldenrust, S. R., Sekijima, Y., Yamashita, T., Ando, Y., Ikeda, S.-I., Gorevic, P., Merlini, G., Kelly, J. W., Skinner, M., Bisbee, A. B., Suhr, O. B.

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Tandem cycles of high-dose melphalan and autologous stem cell transplantation increases the response rate in AL amyloidosis by Dember, L.M, Skinner, M, Fisher, C, Sanchorawala, V, Doros, G, Wright, D.G, Berk, J.L, Quillen, K, Finn, K.T, Seldin, D.C

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High-dose melphalan and autologous stem cell transplantation for AL amyloidosis: recent trends in treatment-related mortality and 1-year survival at a single institution by Seldin, D. C., Andrea, N., Berenbaum, I., Berk, J. L., Connors, L., Dember, L. M., Doros, G., Fennessey, S., Finn, K., Girnius, S., Lerner, A., Libbey, C., Meier-Ewert, H. K., O'Connell, R., O'Hara, C., Quillen, K., Ruberg, F. L., Sam, F., Segal, A., Shelton, A., Skinner, M., Sloan, J. M., Wiesman, J. F., Sanchorawala, V.

“…Treatment with high-dose melphalan chemotherapy supported by hematopoietic rescue with autologous stem cells produces high rates of hematologic responses and…”
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Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis by Adams, David, Gonzalez-Duarte, Alejandra, O’Riordan, William D, Yang, Chih-Chao, Ueda, Mitsuharu, Kristen, Arnt V, Tournev, Ivailo, Schmidt, Hartmut H, Coelho, Teresa, Berk, John L, Lin, Kon-Ping, Vita, Giuseppe, Attarian, Shahram, Planté-Bordeneuve, Violaine, Mezei, Michelle M, Campistol, Josep M, Buades, Juan, Brannagan, Thomas H, Kim, Byoung J, Oh, Jeeyoung, Parman, Yesim, Sekijima, Yoshiki, Hawkins, Philip N, Solomon, Scott D, Polydefkis, Michael, Dyck, Peter J, Gandhi, Pritesh J, Goyal, Sunita, Chen, Jihong, Strahs, Andrew L, Nochur, Saraswathy V, Sweetser, Marianne T, Garg, Pushkal P, Vaishnaw, Akshay K, Gollob, Jared A, Suhr, Ole B

“…Hereditary transthyretin amyloidosis is caused by the deposition of misfolded transthyretin proteins in peripheral nerves and other tissues. This phase 3 trial…”
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Erratum: Tandem cycles of high-dose melphalan and autologous stem cell transplantation increases the response rate in AL amyloidosis by Sanchorawala, V, Wright, D G, Quillen, K, Finn, K T, Dember, L M, Berk, J L, Doros, G, Fisher, C, Skinner, M, Seldin, D C

“…Correction to: Bone Marrow Transplantation (2007) doi:10.1038/sj.bmt.1705746 The authors' affiliations were published online and in this issue incorrectly in…”
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