Search Results - "Berisio, Rita"

Molecular Biomarkers of Disease for Diagnosis and Drug Development by Berisio, Rita

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A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping by Romano, Maria, Ruggiero, Alessia, Squeglia, Flavia, Maga, Giovanni, Berisio, Rita

“…The current coronavirus disease-2019 (COVID-19) pandemic is due to the novel coronavirus SARS-CoV-2. The scientific community has mounted a strong response by…”
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Molecular Immunology in Bacterial Vaccine Discovery by Berisio, Rita

“…The global threat of antimicrobial resistance (AMR) poses a difficult challenge, as underscored by the World Health Organization (WHO), which identifies AMR as…”
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Understanding Molecular Actors of SARS-CoV-2 Virulence to Tackle COVID-19 Outbreak by Berisio, Rita

“…COVID-19 (coronavirus disease 2019) is a threatening disease caused by the novel enveloped, positive-sense, single-stranded RNA beta-coronavirus, denoted as…”
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PGRS domain structures: Doomed to sail the mycomembrane by Berisio, Rita, Delogu, Giovanni

“…The impact of artificial intelligence (AI) in understanding biological processes is potentially immense. Structural elucidation of mycobacterial PE_PGRS is…”
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Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization by Hayafune, Masahiro, Berisio, Rita, Marchetti, Roberta, Silipo, Alba, Kayama, Miyu, Desaki, Yoshitake, Arima, Sakiko, Squeglia, Flavia, Ruggiero, Alessia, Tokuyasu, Ken, Molinaro, Antonio, Kaku, Hanae, Shibuya, Naoto

“…Perception of microbe-associated molecular patterns (MAMPs) through pattern recognition receptors (PRRs) triggers various defense responses in plants. This…”
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Virulence Factors in Mycobacterium tuberculosis Infection: Structural and Functional Studies by Berisio, Rita, Ruggiero, Alessia

“…Tuberculosis (TB) remains one of the main causes of death by infection, especially in immunocompromised patients [...]…”
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Phage-Borne Depolymerases Decrease Klebsiella pneumoniae Resistance to Innate Defense Mechanisms by Majkowska-Skrobek, Grazyna, Latka, Agnieszka, Berisio, Rita, Squeglia, Flavia, Maciejewska, Barbara, Briers, Yves, Drulis-Kawa, Zuzanna

“…produces capsular polysaccharides that are a crucial virulence factor protecting bacteria against innate response mechanisms of the infected host…”
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A global analysis of conservative and non-conservative mutations in SARS-CoV-2 detected in the first year of the COVID-19 world-wide diffusion by Balasco, Nicole, Damaggio, Gianluca, Esposito, Luciana, Villani, Flavia, Berisio, Rita, Colonna, Vincenza, Vitagliano, Luigi

“…The ability of SARS-CoV-2 to rapidly mutate represents a remarkable complicancy. Quantitative evaluations of the effects that these mutations have on the virus…”
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Chemistry of Lipid A: At the Heart of Innate Immunity by Molinaro, Antonio, Holst, Otto, Di Lorenzo, Flaviana, Callaghan, Maire, Nurisso, Alessandra, D'Errico, Gerardino, Zamyatina, Alla, Peri, Francesco, Berisio, Rita, Jerala, Roman, Jiménez-Barbero, Jesús, Silipo, Alba, Martín-Santamaría, Sonsoles

“…In many Gram‐negative bacteria, lipopolysaccharide (LPS) and its lipid A moiety are pivotal for bacterial survival. Depending on its structure, lipid A carries…”
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Investigation of cross-opsonic effect leads to the discovery of PPIase-domain containing protein vaccine candidate to prevent infections by Gram-positive ESKAPE pathogens by Sadones, Océane, Kramarska, Eliza, Laverde, Diana, Berisio, Rita, Huebner, Johannes, Romero-Saavedra, Felipe

“…Enterococcus faecium and Staphylococcus aureus are the Gram-positive pathogens of the ESKAPE group, known to represent a great threat to human health due to…”
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Antimicrobial peptides as an opportunity against bacterial diseases by Galdiero, Stefania, Falanga, Annarita, Berisio, Rita, Grieco, Paolo, Morelli, Giancarlo, Galdiero, Massimiliano

“…Antimicrobial peptides (AMPs) are an heterogeneous group of small amino acidic molecules produced by the innate immune system of a variety of organisms…”
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PE_PGRS proteins of Mycobacterium tuberculosis: A specialized molecular task force at the forefront of host-pathogen interaction by De Maio, Flavio, Berisio, Rita, Manganelli, Riccardo, Delogu, Giovanni

“…To the PE_PGRS protein subfamily belongs a group of surface-exposed mycobacterial antigens that in Mycobacterium tuberculosis (Mtb) H37Rv accounts to more than…”
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Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins by Squeglia, Flavia, Romano, Maria, Ruggiero, Alessia, Maga, Giovanni, Berisio, Rita

“…As intracellular parasites, viruses hijack the host cell metabolic machinery for their replication. Among other cellular proteins, the DEAD-box (DDX) RNA…”
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Polyproline and triple helix motifs in host-pathogen recognition by Berisio, Rita, Vitagliano, Luigi

“…Secondary structure elements often mediate protein-protein interactions. Despite their low abundance in folded proteins, polyproline II (PPII) and its variant,…”
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Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation by Sandomenico, Annamaria, Ruggiero, Alessia, Iaccarino, Emanuela, Oliver, Angela, Squeglia, Flavia, Moreira, Miguel, Esposito, Luciana, Ruvo, Menotti, Berisio, Rita

“…CD59 is an abundant immuno-regulatory human protein that protects cells from damage by inhibiting the complement system. CD59 inhibits the assembly of the…”
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Inhibition of AdeB, AceI, and AmvA Efflux Pumps Restores Chlorhexidine and Benzalkonium Susceptibility in Acinetobacter baumannii ATCC 19606 by Migliaccio, Antonella, Esposito, Eliana Pia, Bagattini, Maria, Berisio, Rita, Triassi, Maria, De Gregorio, Eliana, Zarrilli, Raffaele

“…The management of infections caused by is hindered by its intrinsic tolerance to a wide variety of biocides. The aim of the study was to analyze the role of…”
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Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy by Majkowska-Skrobek, Grażyna, Łątka, Agnieszka, Berisio, Rita, Maciejewska, Barbara, Squeglia, Flavia, Romano, Maria, Lavigne, Rob, Struve, Carsten, Drulis-Kawa, Zuzanna

“…The rise of antibiotic-resistant , a leading nosocomial pathogen, prompts the need for alternative therapies. We have identified and characterized a novel…”
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Structure-Based Development of SARS-CoV-2 Spike Interactors by Squeglia, Flavia, Romano, Maria, Esposito, Luciana, Barra, Giovanni, Campiglia, Pietro, Sala, Marina, Scala, Maria Carmina, Ruggiero, Alessia, Berisio, Rita

“…Coronaviruses, including SARS-CoV-2 (the etiological agent of the current COVID-19 pandemic), rely on the surface spike glycoprotein to access the host cells,…”
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Chemical Basis of Peptidoglycan Discrimination by PrkC, a Key Kinase Involved in Bacterial Resuscitation from Dormancy by Squeglia, Flavia, Marchetti, Roberta, Ruggiero, Alessia, Lanzetta, Rosa, Marasco, Daniela, Dworkin, Jonathan, Petoukhov, Maxim, Molinaro, Antonio, Berisio, Rita, Silipo, Alba

“…Bacterial Ser/Thr kinases modulate a wide number of cellular processes. In Bacillus subtilis, the Ser/Thr kinase PrkC has been shown to induce germination of…”
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