Search Results - "Berin, Cecilia M."

Targeting type 2 immunity and the future of food allergy treatment by Berin, M Cecilia

“…IgE-mediated food allergy affects 6-8% of the population in the United States. Type 2 immune responses are central to the pathogenesis of food allergy, but…”
Get full text

Dysbiosis in food allergy and implications for microbial therapeutics by Berin, M Cecilia

“…The increase in food allergy prevalence in recent years suggests that environmental factors, such as diet and intestinal microbiota, play contributory roles…”
Get full text

Immunopathophysiology of food protein–induced enterocolitis syndrome by Berin, M. Cecilia, PhD

“…There is increasing recognition of the non–IgE-mediated gastrointestinal food allergy known as food protein–induced enterocolitis syndrome (FPIES), with…”
Get full text

Identification of a T follicular helper cell subset that drives anaphylactic IgE by Gowthaman, Uthaman, Chen, Jennifer S, Zhang, Biyan, Flynn, William F, Lu, Yisi, Song, Wenzhi, Joseph, Julie, Gertie, Jake A, Xu, Lan, Collet, Magalie A, Grassmann, Jessica D S, Simoneau, Tregony, Chiang, David, Berin, M Cecilia, Craft, Joseph E, Weinstein, Jason S, Williams, Adam, Eisenbarth, Stephanie C

“…Cross-linking of high-affinity immunoglobulin E (IgE) results in the life-threatening allergic reaction anaphylaxis. Yet the cellular mechanisms that induce B…”
Get full text

Food Protein-Induced Enterocolitis Syndrome by Nowak-Wegrzyn, Anna, Berin, M. Cecilia, Mehr, Sam

“…Food protein-induced enterocolitis syndrome (FPIES) is a non–IgE-mediated food allergy that manifests with projectile, repetitive emesis that can be followed…”
Get full text

Systemic innate immune activation in food protein–induced enterocolitis syndrome by Goswami, Ritobrata, PhD, Blazquez, Ana Belen, PhD, Kosoy, Roman, PhD, Rahman, Adeeb, PhD, Nowak-Węgrzyn, Anna, MD, PhD, Berin, M. Cecilia, PhD

“…Background Food protein–induced enterocolitis syndrome (FPIES) is a non–IgE-mediated food allergy of infancy whose pathophysiology is poorly understood…”
Get full text

Epicutaneous immunotherapy induces gastrointestinal LAP+ regulatory T cells and prevents food-induced anaphylaxis by Tordesillas, Leticia, PhD, Mondoulet, Lucie, PhD, Blazquez, Ana Belen, PhD, Benhamou, Pierre-Henri, PhD, Sampson, Hugh A., MD, Berin, M. Cecilia, PhD

“…Background The attempt to induce oral tolerance as a treatment for food allergy has been hampered by a lack of sustained clinical protection. Immunotherapy by…”
Get full text

Can we produce true tolerance in patients with food allergy? by Berin, M. Cecilia, PhD, Mayer, Lloyd, MD

“…Immune tolerance is defined as nonresponsiveness of the adaptive immune system to antigens. Immune mechanisms preventing inappropriate immune reactivity to…”
Get full text

Update on Food Protein–Induced Enterocolitis Syndrome (FPIES) by Baker, Mary Grace, Cecilia Berin, M., Sicherer, Scott

“…Purpose of Review Food protein–induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy characterized by delayed, and potentially severe,…”
Get full text

Epicutaneous immunotherapy for the treatment of peanut allergy in children and young adults by Jones, Stacie M., MD, Sicherer, Scott H., MD, Burks, A. Wesley, MD, Leung, Donald Y.M., MD, Lindblad, Robert W., MD, Dawson, Peter, PhD, Henning, Alice K., MS, Berin, M. Cecilia, PhD, Chiang, David, MSc, Vickery, Brian P., MD, Pesek, Robbie D., MD, Cho, Christine B., MD, Davidson, Wendy F., PhD, Plaut, Marshall, MD, Sampson, Hugh A., MD, Wood, Robert A., MD

“…Background Peanut allergy is common, life-threatening, and without therapeutic options. We evaluated peanut epicutaneous immunotherapy (EPIT) by using Viaskin…”
Get full text

Report from the National Institute of Allergy and Infectious Diseases workshop on “Atopic dermatitis and the atopic march: Mechanisms and interventions” by Davidson, Wendy F., Leung, Donald Y.M., Beck, Lisa A., Berin, Cecilia M., Boguniewicz, Mark, Busse, William W., Chatila, Talal A., Geha, Raif S., Gern, James E., Guttman-Yassky, Emma, Irvine, Alan D., Kim, Brian S., Kong, Heidi H., Lack, Gideon, Nadeau, Kari C., Schwaninger, Julie, Simpson, Angela, Simpson, Eric L., Spergel, Jonathan M., Togias, Alkis, Wahn, Ulrich, Wood, Robert A., Woodfolk, Judith A., Ziegler, Steven F., Plaut, Marshall

“…Atopic dermatitis (AD) affects up to 20% of children worldwide and is an increasing public health problem, particularly in developed countries. Although AD in…”
Get full text

PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs by Tordesillas, Leticia, Lozano-Ojalvo, Daniel, Dunkin, David, Mondoulet, Lucie, Agudo, Judith, Merad, Miriam, Sampson, Hugh A., Berin, M. Cecilia

“…The skin immune system must discriminate between innocuous antigens and pathogens. Antigen applied topically using a Viaskin® patch elicits immune tolerance…”
Get full text

Humoral and cellular responses to casein in patients with food protein–induced enterocolitis to cow's milk by Caubet, Jean Christoph, MD, Bencharitiwong, Ramon, PhD, Ross, Andrew, BA, Sampson, Hugh A., MD, Berin, M. Cecilia, PhD, Nowak-Węgrzyn, Anna, MD

“…Background Food protein–induced enterocolitis syndrome (FPIES) is a non–IgE-mediated food allergy manifesting within 1 to 4 hours of food ingestion with…”
Get full text

Heparin reduces nonspecific eosinophil staining artifacts in mass cytometry experiments by Rahman, Adeeb H., Tordesillas, Leticia, Berin, M. Cecilia

“…The analysis of heterogeneous cell samples by mass cytometry (CyTOF) relies on the assumption that metal labeled antibodies accurately bind to their target…”
Get full text

Oral immunotherapy induces local protective mechanisms in the gastrointestinal mucosa by Leonard, Stephanie A., MD, Martos, Gustavo, PhD, Wang, Wei, MD, Nowak-Węgrzyn, Anna, MD, Berin, M. Cecilia, PhD

“…Background Oral immunotherapy (OIT) is a promising treatment for food allergy. Studies are needed to elucidate mechanisms of clinical protection and to…”
Get full text

Untargeted serum metabolomic analysis reveals a role for purinergic signaling in FPIES by Lozano-Ojalvo, Daniel, Chen, Xin, Dunkin, David, Agashe, Charuta, Baker, Mary Grace, Bird, J. Andrew, Molina, Elena, Nowak-Wegrzyn, Anna, Berin, M. Cecilia

“…[Display omitted] Food protein–induced enterocolitis syndrome (FPIES) is a non–IgE-mediated food allergy with a typical onset in infancy. Its symptoms are…”
Get full text

Mechanisms underlying differential food allergy response to heated egg by Martos, Gustavo, BS, Lopez-Exposito, Ivan, PhD, Bencharitiwong, Ramon, BS, Berin, M. Cecilia, PhD, Nowak-Węgrzyn, Anna, MD

“…Background Egg white proteins are usually subjected to heating, making them edible for the majority of children with egg allergy. Objective We sought to…”
Get full text

Mucosal immunology of tolerance and allergy in the gastrointestinal tract by Steele, Lauren, Mayer, Lloyd, Cecilia Berin, M.

“…The mucosal immune system typically exists in a state of active tolerance to food antigens and commensal bacteria. Tolerance to food proteins is induced in…”
Get full text

Emerging Food Allergy Biomarkers by Patil, Sarita U., Bunyavanich, Supinda, Berin, M. Cecilia

“…The management of food allergy is complicated by the lack of highly predictive biomarkers for diagnosis and prediction of disease course. The measurement of…”
Get full text

Epicutaneous immunotherapy for treatment of peanut allergy: Follow-up from the Consortium for Food Allergy Research by Scurlock, Amy M., Burks, A. Wesley, Sicherer, Scott H., Leung, Donald Y.M., Kim, Edwin H., Henning, Alice K., Dawson, Peter, Lindblad, Robert W., Berin, M. Cecilia, Cho, Christine B., Davidson, Wendy F., Plaut, Marshall, Sampson, Hugh A., Wood, Robert A., Jones, Stacie M.

“…Consortium for Food Allergy Research investigators previously reported 52-week outcomes from a randomized controlled trial of peanut epicutaneous…”
Get full text