Search Results - "Bergum, Nikolas"

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  1. 1

    µ-Opioid Receptors Expressed by Intrinsically Photosensitive Retinal Ganglion Cells Contribute to Morphine-Induced Behavioral Sensitization by Bergum, Nikolas, Berezin, Casey-Tyler, King, Connie M, Vigh, Jozsef

    “…Opioid drugs are the most effective tools for treating moderate to severe pain. Despite their analgesic efficacy, long-term opioid use can lead to drug…”
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    Journal Article
  2. 2

    A retinal contribution to opioid-induced sleep disorders? by Bergum, Nikolas, Berezin, Casey-Tyler, Vigh, Jozsef

    Published in Frontiers in neuroscience (05-08-2022)
    “…Chronic opioid use is linked to persistent and severe sleep/wake disturbances in patients. These opioid-related sleep problems increase risk for developing…”
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    Journal Article
  3. 3

    Morphine Accumulates in the Retina Following Chronic Systemic Administration by Bergum, Nikolas, Berezin, Casey-Tyler, Dooley, Gregory, Vigh, Jozsef

    Published in Pharmaceuticals (Basel, Switzerland) (25-04-2022)
    “…Opioid transport into the central nervous system is crucial for the analgesic efficacy of opioid drugs. Thus, the pharmacokinetics of opioid analgesics such as…”
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    Journal Article
  4. 4

    Morphine pharmacokinetics and opioid transporter expression at the blood-retina barrier of male and female mice by Berezin, Casey-Tyler, Bergum, Nikolas, Torres Lopez, Glenda M, Vigh, Jozsef

    Published in Frontiers in pharmacology (14-06-2023)
    “…Opioids are effective analgesics for treating moderate to severe pain, however, their use must be weighed against their dangerous side effects. Investigations…”
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    Journal Article
  5. 5

    Endogenous opioid signaling in the retina modulates sleep/wake activity in mice by Berezin, Casey-Tyler, Bergum, Nikolas, Luchini, Kes A., Curdts, Sierra, Korkis, Christian, Vigh, Jozsef

    “…Circadian sleep/wake rhythms are synchronized to environmental light/dark cycles in a process known as photoentrainment. We have previously shown that…”
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    Journal Article
  6. 6

    Dopamine enhances GABAA receptor-mediated current amplitude in a subset of intrinsically photosensitive retinal ganglion cells by Bergum, Nikolas, Berezin, Casey-Tyler, Vigh, Jozsef

    Published in Journal of neurophysiology (03-08-2024)
    “…Neuromodulation in the retina is crucial for effective processing of retinal signal at different levels of illuminance. Intrinsically photosensitive retinal…”
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    Journal Article
  7. 7

    Dopamine enhances GABA A receptor-mediated current amplitude in a subset of intrinsically photosensitive retinal ganglion cells by Bergum, Nikolas, Berezin, Casey-Tyler, Vigh, Jozsef

    Published in Journal of neurophysiology (01-08-2024)
    “…Neuromodulation in the retina is crucial for effective processing of retinal signal at different levels of illuminance. Intrinsically photosensitive retinal…”
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    Journal Article
  8. 8

    A Retinal Contribution to Chronic Opioid-Induced Sleep/Wake Dysfunction by Bergum, Nikolas

    Published 01-01-2023
    “…Light is among the most important environmental factors that regulate mammalian sleep/circadian behaviors. Melanopsin-expressing intrinsically photosensitive…”
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    Dissertation