Search Results - "Bergum, Nikolas"
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µ-Opioid Receptors Expressed by Intrinsically Photosensitive Retinal Ganglion Cells Contribute to Morphine-Induced Behavioral Sensitization
Published in International journal of molecular sciences (14-12-2022)“…Opioid drugs are the most effective tools for treating moderate to severe pain. Despite their analgesic efficacy, long-term opioid use can lead to drug…”
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A retinal contribution to opioid-induced sleep disorders?
Published in Frontiers in neuroscience (05-08-2022)“…Chronic opioid use is linked to persistent and severe sleep/wake disturbances in patients. These opioid-related sleep problems increase risk for developing…”
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Journal Article -
3
Morphine Accumulates in the Retina Following Chronic Systemic Administration
Published in Pharmaceuticals (Basel, Switzerland) (25-04-2022)“…Opioid transport into the central nervous system is crucial for the analgesic efficacy of opioid drugs. Thus, the pharmacokinetics of opioid analgesics such as…”
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Journal Article -
4
Morphine pharmacokinetics and opioid transporter expression at the blood-retina barrier of male and female mice
Published in Frontiers in pharmacology (14-06-2023)“…Opioids are effective analgesics for treating moderate to severe pain, however, their use must be weighed against their dangerous side effects. Investigations…”
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Journal Article -
5
Endogenous opioid signaling in the retina modulates sleep/wake activity in mice
Published in Neurobiology of sleep and circadian rhythms (01-11-2022)“…Circadian sleep/wake rhythms are synchronized to environmental light/dark cycles in a process known as photoentrainment. We have previously shown that…”
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Journal Article -
6
Dopamine enhances GABAA receptor-mediated current amplitude in a subset of intrinsically photosensitive retinal ganglion cells
Published in Journal of neurophysiology (03-08-2024)“…Neuromodulation in the retina is crucial for effective processing of retinal signal at different levels of illuminance. Intrinsically photosensitive retinal…”
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Journal Article -
7
Dopamine enhances GABA A receptor-mediated current amplitude in a subset of intrinsically photosensitive retinal ganglion cells
Published in Journal of neurophysiology (01-08-2024)“…Neuromodulation in the retina is crucial for effective processing of retinal signal at different levels of illuminance. Intrinsically photosensitive retinal…”
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Journal Article -
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A Retinal Contribution to Chronic Opioid-Induced Sleep/Wake Dysfunction
Published 01-01-2023“…Light is among the most important environmental factors that regulate mammalian sleep/circadian behaviors. Melanopsin-expressing intrinsically photosensitive…”
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Dissertation