Search Results - "Bergström Lind, Sara"
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Evaluation of affinity-purification coupled to mass spectrometry approaches for capture of short linear motif-based interactions
Published in Analytical biochemistry (15-02-2023)“…Low affinity and transient protein-protein interactions, such as short linear motif (SLiM)-based interactions, require dedicated experimental tools for…”
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2
Interleukin-13 Treatment of Living Lung Tissue Model Alters the Metabolome and Proteome-A Nano-DESI MS Metabolomics and Shotgun Proteomics Study
Published in International journal of molecular sciences (01-05-2024)“…Asthma is a chronic respiratory disease with one of the largest numbers of cases in the world; thus, constant investigation and technical development are…”
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3
Qualitative analysis of antibody-drug conjugates (ADCs): an experimental comparison of analytical techniques of cysteine-linked ADCs
Published in Analyst (London) (05-11-2018)“…Antibody-drug conjugates (ADCs) are an emerging type of biotherapeutics that utilize multiple tissue-specific antibodies combined with a range of linker…”
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4
Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells
Published in PLoS neglected tropical diseases (11-12-2017)“…Giardia intestinalis is a non-invasive protozoan parasite that causes giardiasis in humans, the most common form of parasite-induced diarrhea. Disease…”
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5
The Human Adenovirus 2 Transcriptome: an Amazing Complexity of Alternatively Spliced mRNAs
Published in Journal of virology (28-01-2021)“…We used the Nanopore long-read sequencing platform to demonstrate how amazingly complex the human adenovirus type 2 (Ad2) transcriptome is, with a flexible…”
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6
Phosphorylation Time‐Course Study of the Response during Adenovirus Type 2 Infection
Published in Proteomics (Weinheim) (01-04-2020)“…PTMs such as phosphorylations are usually involved in signal transduction pathways. To investigate the temporal dynamics of phosphoproteome changes upon viral…”
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7
Parallel Proteomic Workflow for Mass Spectrometric Analysis of Tissue Samples Preserved by Different Methods
Published in Analytical chemistry (Washington) (01-05-2018)“…Formalin-fixed and paraffin-embedded (FFPE) and optimal cutting temperature (OCT)-embedded and frozen tissue specimens in biobanks are highly valuable in…”
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8
Plasma-derived extracellular vesicles from myocardial infarction patients inhibits tumor necrosis factor-alpha induced cardiac cell death
Published in Current research in translational medicine (01-05-2022)“…Extracellular vesicles (EVs) derived exogenously from pluripotent stem cells or endogenously from healthy human serum exert cardioprotective effects after…”
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Potential Use of Supercharging Agents for Improved Mass Spectrometric Analysis of Monoclonal Antibodies and Antibody–Drug Conjugates
Published in Journal of the American Society for Mass Spectrometry (06-07-2022)“…The addition of supercharging (SC) reagents in electrospray ionization coupled mass spectrometry (ESI-MS) has demonstrated several advantages for protein…”
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10
Time-resolved proteomics of adenovirus infected cells
Published in PloS one (25-09-2018)“…Viral infections cause large problems in the world and deeper understanding of the disease mechanisms is needed. Here we present an analytical strategy to…”
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Magnetic Beads for Desalting of Monoclonal Antibodies and Antibody–Drug Conjugates
Published in Analytical chemistry (Washington) (07-07-2020)“…Characterization of antibody–drug conjugates (ADCs) using mass spectrometry (MS) is important in drug discovery and formulation development and as part of the…”
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12
Proteomic comparison between different tissue preservation methods for identification of promising biomarkers of urothelial bladder cancer
Published in Scientific reports (07-04-2021)“…Samples in biobanks are generally preserved by formalin-fixation and paraffin-embedding (FFPE) and/or optimal cutting temperature compound (OCT)-embedding and…”
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13
Posttranscriptional Regulation in Adenovirus Infected Cells
Published in Journal of proteome research (03-02-2017)“…A deeper understanding of how viruses reprogram their hosts for production of progeny is needed to combat infections. Most knowledge on the regulation of…”
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14
Distinct temporal changes in host cell lncRNA expression during the course of an adenovirus infection
Published in Virology (New York, N.Y.) (01-05-2016)“…Abstract The deregulation of cellular long non-coding RNA (lncRNA) expression during a human adenovirus infection was studied by deep sequencing. Expression of…”
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15
Inhibition properties of free and conjugated leupeptin analogues
Published in FEBS open bio (01-12-2020)“…Leupeptin is a naturally occurring inhibitor of various proteases, in particular serine proteases. Following its discovery, the inhibitory properties of…”
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Application of triple quadrupole mass spectrometry for the characterization of antibody–drug conjugates
Published in Analytical and bioanalytical chemistry (01-05-2019)“…Antibody–drug conjugates (ADCs) are an inherently heterogeneous class of biotherapeutics, the development of which requires extensive characterization…”
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17
Proteomic analysis of urinary biomarker candidates for nonmuscle invasive bladder cancer
Published in Proteomics (Weinheim) (01-01-2012)“…Nonmuscle invasive tumors of the bladder often recur and thereby bladder cancer patients need regular re‐examinations which are invasive, unpleasant, and…”
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18
Identification of the adenovirus type 2 C-168 protein
Published in Virus research (15-06-2017)“…•Identification of the adenovirus type 2 C-168 by mass spectrometry.•Molecular weight of C-168 corresponds to prediction from open reading frame.•Candidte RNA…”
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A flow-through nanoporous alumina trypsin bioreactor for mass spectrometry peptide fingerprinting
Published in Journal of proteomics (10-02-2018)“…Mass spectrometry-based proteomics benefits from efficient digestion of protein samples. In this study, trypsin was immobilized on nanoporous anodized alumina…”
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Transcriptomic and proteomic analyses reveal new insights into the regulation of immune pathways during adenovirus type 2 infection
Published in BMC microbiology (14-01-2019)“…Human adenovirus (Ad) infection leads to the changes of host cell gene expression and biosynthetic processes. Transcriptomics in adenovirus type 2…”
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