Search Results - "Bergsten, P."
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1
Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretion
Published in Scientific reports (05-07-2017)“…In obesity fasting levels of both glucagon and insulin are elevated. In these subjects fasting levels of the free fatty acid palmitate are raised. We have…”
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2
Functional differences between aggregated and dispersed insulin-producing cells
Published in Diabetologia (01-07-2013)“…Aims/hypothesis Beta cells situated in the islet of Langerhans respond more vigorously to glucose than do dissociated beta cells. Mechanisms for this…”
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3
Islet protein profiling
Published in Diabetes, obesity & metabolism (01-11-2009)“…Islet protein profiling is defined as generation of extended protein expression data sets from islets or islet cells. Islets from rodent control and animal…”
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4
A 6‐month randomized, double‐blind, placebo‐controlled trial of weekly exenatide in adolescents with obesity
Published in Pediatric obesity (01-07-2020)“…Summary Background Pharmacological treatment options for adolescents with obesity are very limited. Glucagon‐like‐peptide‐1 (GLP‐1) receptor agonist could be a…”
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5
Glucose-induced changes of multiple mouse islet proteins analysed by two-dimensional gel electrophoresis and mass spectrometry
Published in Diabetologia (01-03-2005)“…The aim of this study was to investigate molecular mechanisms of glucose-induced changes in islets of Langerhans by analysing global changes in protein…”
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6
Observers for Takagi-Sugeno fuzzy systems
Published in IEEE transactions on systems, man and cybernetics. Part B, Cybernetics (01-02-2002)“…We focus on the analysis and design of two different sliding mode observers for dynamic Takagi-Sugeno (TS) fuzzy systems. A nonlinear system of this class is…”
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7
Slow and fast oscillations of cytoplasmic Ca2+ in pancreatic islets correspond to pulsatile insulin release
Published in The American journal of physiology (01-02-1995)“…Cytoplasmic Ca2+ concentration ([Ca2+]i) and insulin secretion were monitored in single ob/ob mouse pancreatic islets stimulated by glucose. After culture in…”
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8
Synchronous oscillations of cytoplasmic Ca2+ and insulin release in glucose-stimulated pancreatic islets
Published in The Journal of biological chemistry (25-03-1994)“…The cytoplasmic Ca2+ concentration ([Ca2+]i) was measured in single pancreatic mouse islets superfused in a system allowing concomitant recordings of insulin…”
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9
Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets
Published in Diabetes (New York, N.Y.) (01-05-1993)“…Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets. P Bergsten and B Hellman Department of Medical Cell…”
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10
Glucose-induced de novo synthesis of fatty acyls causes proportional increases in INS-1E cellular lipids
Published in NMR in biomedicine (01-05-2008)“…Raised concentrations of glucose for extended periods of time have detrimental effects on the insulin‐producing β‐cell. As de novo synthesis of lipids has been…”
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11
Oscillations in oxygen tension and insulin release of individual pancreatic ob/ob mouse islets
Published in Diabetologia (01-10-2000)“…The role of beta-cell metabolism for generation of oscillatory insulin release was investigated by simultaneous measurements of oxygen tension (pO2) and…”
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12
Ascorbic Acid Transport and Distribution in Human B Lymphocytes
Published in Archives of biochemistry and biophysics (20-02-1995)“…Ascorbic acid (vitamin C) transport was investigated inhuman B lymphocytes. The vitamin was transported by two components. The first was a high-affinity…”
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13
Glucose induces oscillatory Ca2+ signalling and insulin release in human pancreatic beta cells
Published in Diabetologia (01-09-1994)“…Mechanisms of pulsatile insulin release in man were explored by studying the induction of oscillatory Ca2+ signals in individual beta cells and islets isolated…”
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14
Millimolar concentrations of ascorbic acid in purified human mononuclear leukocytes. Depletion and reaccumulation
Published in The Journal of biological chemistry (15-02-1990)“…Ascorbic acid (vitamin C) was found in isolated human mononuclear leukocytes and their purified components in millimolar concentration. Intracellular ascorbic…”
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15
The human-based multisensor fusion method for artificial nose and tongue sensor data
Published in IEEE transactions on instrumentation and measurement (01-10-1998)“…Presently, an increased interest is apparent for the development of integrated human-like smell and taste sensing capabilities, e.g. for chemical, paper pulp,…”
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16
Glucose-induced cycles of insulin release can be resolved into distinct periods of secretory activity
Published in Biochemical and biophysical research communications (14-05-1993)“…The periodic behaviour of glucose-stimulated insulin release was studied using islets isolated from ob/ob-mice and rats. A single islet was perifused at a rate…”
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17
Ascorbic acid accumulation and transport in human fibroblasts
Published in Biochemical journal (01-09-1993)“…As the initial step in the use of fibroblasts as a model system for 'in situ kinetics', ascorbic acid (vitamin C) accumulation in normal human fibroblasts was…”
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18
Oleate increase neutral lipid accumulation, cellular respiration and rescues palmitate-exposed GLP-1 secreting cells by reducing ceramide-induced ROS
Published in Biochimie (01-04-2019)“…Fatty acids (FAs), and especially monounsaturated FAs (MUFAs) stimulate GLP-1 release. However, lipotoxicity is indicated in GLP-1 secreting cells following…”
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High DPP-4 Concentrations in Adolescents Are Associated With Low Intact GLP-1
Published in The journal of clinical endocrinology and metabolism (01-08-2018)“…Abstract Context Dipeptidyl peptidase 4 (DPP-4) metabolizes glucagon-like peptide-1 (GLP-1), and increased DPP4 levels are associated with obesity and visceral…”
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20
Fasting hyperglucagonemia and altered glucagon dynamics during OGTT in childhood obesity
Published in Appetite (01-06-2015)Get full text
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