Search Results - "Bergs, Amelie"
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BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons
Published in Nature communications (26-07-2021)“…Optogenetic manipulation of neuronal activity through excitatory and inhibitory opsins has become an indispensable experimental strategy in neuroscience…”
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All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals
Published in Nature communications (06-04-2023)“…Excitable cells can be stimulated or inhibited by optogenetics. Since optogenetic actuation regimes are often static, neurons and circuits can quickly adapt,…”
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Rhodopsin-based voltage imaging tools for use in muscles and neurons of Caenorhabditis elegans
Published in Proceedings of the National Academy of Sciences - PNAS (20-08-2019)“…Genetically encoded voltage indicators (GEVIs) based on microbial rhodopsins utilize the voltage-sensitive fluorescence of all-trans retinal (ATR), while in…”
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Expanding the Optogenetics Toolkit by Topological Inversion of Rhodopsins
Published in Cell (01-11-2018)“…Targeted manipulation of activity in specific populations of neurons is important for investigating the neural circuit basis of behavior. Optogenetic…”
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Functionally asymmetric motor neurons contribute to coordinating locomotion of Caenorhabditis elegans
Published in eLife (11-09-2018)“…Locomotion circuits developed in simple animals, and circuit motifs further evolved in higher animals. To understand locomotion circuit motifs, they must be…”
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RIM and RIM-Binding Protein Localize Synaptic CaV2 Channels to Differentially Regulate Transmission in Neuronal Circuits
Published in The Journal of neuroscience (31-07-2024)“…At chemical synapses, voltage-gated Ca channels (VGCCs) translate electrical signals into a trigger for synaptic vesicle (SV) fusion. VGCCs and the Ca…”
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Rhodopsin optogenetic toolbox v2.0 for light-sensitive excitation and inhibition in Caenorhabditis elegans
Published in PloS one (01-02-2018)“…In optogenetics, rhodopsins were established as light-driven tools to manipulate neuronal activity. However, during long-term photostimulation using…”
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Tools and methods for cell ablation and cell inhibition in Caenorhabditis elegans
Published in Genetics (Austin) (07-08-2024)“…To understand the function of cells such as neurons within an organism, it can be instrumental to inhibit cellular function, or to remove the cell (type) from…”
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Microbial Rhodopsin Optogenetic Tools: Application for Analyses of Synaptic Transmission and of Neuronal Network Activity in Behavior
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Over the past 15 years, optogenetic methods have revolutionized neuroscientific and cell biological research, also in the nematode Caenorhabditis elegans. In…”
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Optogenetischer Werkzeugkasten für neue experimentelle Ansätze
Published in Biospektrum (01-06-2019)“…In rhodopsin-based optogenetics the light-activatable cation channel ChR2 is employed to selectively gain control over single neurons. As arising experimental…”
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