Search Results - "Bergquist, Lars"

Impact of chemical modification of sulfamidase on distribution to brain interstitial fluid and to CSF after an intravenous administration in awake, freely-moving rats by Janson, Juliette, Andersson, Gudrun, Bergquist, Lars, Eriksson, Maria, Folgering, Joost H.A.

“…Mucopolysaccharidosis III A (MPS IIIA) is an autosomal recessive lysosomal storage disorder caused by deficiency of the enzyme sulfamidase. The disorder…”
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Piperidine amides as 11β-hydroxysteroid dehydrogenase type 1 inhibitors by Flyrén, Katarina, Bergquist, Lars O., Castro, Victor M., Fotsch, Christopher, Johansson, Lars, St. Jean, David J., Sutin, Lori, Williams, Meredith

“…Compound 1 was identified as a potent 11β-HSD1 inhibitor in a HTS screen. Synthesis and inhibitory potency of analogs to 1 are reported. A series of piperidine…”
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Distribution of chemically modified rhSulfamidase to CNS monitored by brain microdialysis and repeated CSF sampling after intravenous administration in rat by Janson, Juliette, Andersson, Gudrun, Bergquist, Lars, Eriksson, Maria, Folgering, Joost H.A.

“…Mucopolysaccharidosis type IIIA (MPS IIIA) is an autosomal recessive disorder caused by absence or deficiency of the lysosomal enzyme sulfamidase. Glycans of…”
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Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members by Lundgren, M, Ström, L, Bergquist, L O, Skog, S, Heiden, T, Stavnezer, J, Severinson, E

“…Previous studies have indicated that transcription of germ-line (GL) CH genes is necessary to obtain immunoglobulin (Ig) class switching. We report here a…”
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Oxazolones as potent inhibitors of 11β-hydroxysteroid dehydrogenase type 1 by Sutin, Lori, Andersson, Sören, Bergquist, Lars, Castro, Victor M., Danielsson, Eva, James, Stephen, Henriksson, Martin, Johansson, Lars, Kaiser, Christina, Flyrén, Katarina, Williams, Meredith

“…Compounds of general formula 1 were found to be potent inhibitors of 11β-HSD1. Synthesis, structure–activity relationship and metabolic stability of these…”
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Oxazolones as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 by Sutin, Lori, Andersson, Sören, Bergquist, Lars, Castro, Victor M, Danielsson, Eva, James, Stephen, Henriksson, Martin, Johansson, Lars, Kaiser, Christina, Flyrén, Katarina, Williams, Meredith

“…2,5,5-Trisubstituted oxazolones were identified as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1). The synthesis,…”
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Piperidine amides as 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by Flyrén, Katarina, Bergquist, Lars O, Castro, Victor M, Fotsch, Christopher, Johansson, Lars, St Jean, Jr, David J, Sutin, Lori, Williams, Meredith

“…A series of piperidine amide inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) were identified via modifications of the HTS hit…”
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Arronax' minnen by Sandstroem, Yvonne L.

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