Search Results - "Bergquist, Jake A"

Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy by Zhu, Weiquan, Shi, Dallas S, Winter, Jacob M, Rich, Bianca E, Tong, Zongzhong, Sorensen, Lise K, Zhao, Helong, Huang, Yi, Tai, Zhengfu, Mleynek, Tara M, Yoo, Jae Hyuk, Dunn, Christine, Ling, Jing, Bergquist, Jake A, Richards, Jackson R, Jiang, Amanda, Lesniewski, Lisa A, Hartnett, M Elizabeth, Ward, Diane M, Mueller, Alan L, Ostanin, Kirill, Thomas, Kirk R, Odelberg, Shannon J, Li, Dean Y

“…The devastating sequelae of diabetes mellitus include microvascular permeability, which results in retinopathy. Despite clinical and scientific advances, there…”
Get full text

Investigation into the importance of using natural PVCs and pathological models for potential-based ECGI validation by Bear, Laura R, Bergquist, Jake A, Abell, Emma, Cochet, Hubert, MacLeod, Rob S, Dubois, Remi, Serinagaoglu, Yesim

“…Premature ventricular contractions (PVCs) are one of the most commonly targeted pathologies for ECGI validation, often through ventricular stimulation to mimic…”
Get full text

Tipping the scales of understanding: An engineering approach to design and implement whole-body cardiac electrophysiology experimental models by Zenger, Brian, Bergquist, Jake A, Busatto, Anna, Good, Wilson W, Rupp, Lindsay C, Sharma, Vikas, MacLeod, Rob S

“…The study of cardiac electrophysiology is built on experimental models that span all scales, from ion channels to whole-body preparations. Novel discoveries…”
Get full text

All Roads Lead to Rome: Diverse Etiologies of Tricuspid Regurgitation Create a Predictable Constellation of Right Ventricular Shape Changes by Orkild, Benjamin A, Zenger, Brian, Iyer, Krithika, Rupp, Lindsay C, Ibrahim, Majd M, Khashani, Atefeh G, Perez, Maura D, Foote, Markus D, Bergquist, Jake A, Morris, Alan K, Kim, Jiwon J, Steinberg, Benjamin A, Selzman, Craig, Ratcliffe, Mark B, MacLeod, Rob S, Elhabian, Shireen, Morgan, Ashley E

“…Myriad disorders cause right ventricular (RV) dilation and lead to tricuspid regurgitation (TR). Because the thin-walled, flexible RV is mechanically coupled…”
Get full text

UncertainSCI: Uncertainty quantification for computational models in biomedicine and bioengineering by Narayan, Akil, Liu, Zexin, Bergquist, Jake A., Charlebois, Chantel, Rampersad, Sumientra, Rupp, Lindsay, Brooks, Dana, White, Dan, Tate, Jess, MacLeod, Rob S.

“…Computational biomedical simulations frequently contain parameters that model physical features, material coefficients, and physiological effects, whose values…”
Get full text

Left atrial functional changes associated with repeated catheter ablations for atrial fibrillation by Dong, Jiawei, Kwan, Eugene, Bergquist, Jake A, Dosdall, Derek J, DiBella, Edward V, MacLeod, Rob S, Stoddard, Gregory J, Konstantidinis, Klitos, Steinberg, Benjamin A, Bunch, T Jared, Ranjan, Ravi

“…The impact of repeated atrial fibrillation (AF) ablations on left atrial (LA) mechanical function remains uncertain, with limited long-term follow-up data…”
Get full text

Reducing Line-of-Block Artifacts in Cardiac Activation Maps Estimated Using ECG Imaging: A Comparison of Source Models and Estimation Methods by Schuler, Steffen, Schaufelberger, Matthias, Bear, Laura R., Bergquist, Jake A., Cluitmans, Matthijs J. M., Coll-Font, Jaume, Onak, Onder N., Zenger, Brian, Loewe, Axel, MacLeod, Rob S., Brooks, Dana H., Dossel, Olaf

“…Objective: To investigatecardiac activation maps estimated using electrocardiographic imaging and to find methods reducing line-of-block (LoB) artifacts, while…”
Get full text

Estimation and Validation of Cardiac Conduction Velocity and Wavefront Reconstruction Using Epicardial and Volumetric Data by Good, Wilson W., Gillette, Karli K., Zenger, Brian, Bergquist, Jake A., Rupp, Lindsay C., Tate, Jess, Anderson, Devan, Gsell, Matthias A.F., Plank, Gernot, MacLeod, Rob S.

“…Objective: In this study, we have used whole heart simulations parameterized with large animal experiments to validate three techniques (two from the…”
Get full text

Novel experimental model for studying the spatiotemporal electrical signature of acute myocardial ischemia: a translational platform by Zenger, Brian, Good, Wilson W, Bergquist, Jake A, Burton, Brett M, Tate, Jess D, Berkenbile, Leo, Sharma, Vikas, MacLeod, Rob S

“…Myocardial ischemia is one of the most common cardiovascular pathologies and can indicate many severe and life threatening diseases. Despite these risks,…”
Get more information

The electrocardiographic forward problem: A benchmark study by Bergquist, Jake A., Good, Wilson W., Zenger, Brian, Tate, Jess D., Rupp, Lindsay C., MacLeod, Rob S.

“…Electrocardiographic forward problems are crucial components for noninvasive electrocardiographic imaging (ECGI) that compute torso potentials from cardiac…”
Get full text

Reconstruction of cardiac position using body surface potentials by Bergquist, Jake A., Coll-Font, Jaume, Zenger, Brian, Rupp, Lindsay C., Good, Wilson W., Brooks, Dana H., MacLeod, Rob S.

“…Electrocardiographic imaging (ECGI) is a noninvasive technique to assess the bioelectric activity of the heart which has been applied to aid in clinical…”
Get full text

Ablation-induced left atrial mechanical dysfunction recovers in weeks after ablation by Dong, Jiawei, Kwan, Eugene, Bergquist, Jake A., Steinberg, Benjamin A., Dosdall, Derek J., DiBella, Edward V. R., MacLeod, Rob S., Bunch, T. Jared, Ranjan, Ravi

“…Background The immediate impact of catheter ablation on left atrial mechanical function and the timeline for its recovery in patients undergoing ablation for…”
Get full text

Influence of material parameter variability on the predicted coronary artery biomechanical environment via uncertainty quantification by Berggren, Caleb C., Jiang, David, Jack Wang, Y. F., Bergquist, Jake A., Rupp, Lindsay C., Liu, Zexin, MacLeod, Rob S., Narayan, Akil, Timmins, Lucas H.

“…Central to the clinical adoption of patient-specific modeling strategies is demonstrating that simulation results are reliable and safe. Indeed, simulation…”
Get full text

Transient recovery of epicardial and torso ST-segment ischemic signals during cardiac stress tests: A possible physiological mechanism by Zenger, Brian, Good, Wilson W., Bergquist, Jake A., Rupp, Lindsay C., Perez, Maura, Stoddard, Gregory J., Sharma, Vikas, MacLeod, Rob S.

“…Acute myocardial ischemia has several characteristic ECG findings, including clinically detectable ST-segment deviations. However, the sensitivity and…”
Get full text

Combining endocardial mapping and electrocardiographic imaging (ECGI) for improving PVC localization: A feasibility study by Good, Wilson W., Zenger, Brian, Bergquist, Jake A., Rupp, Lindsay C., Gillette, Karli, Angel, Nathan, Chou, Derrick, Plank, Gernot, MacLeod, Rob S.

“…Accurate reconstruction of cardiac activation wavefronts is crucial for clinical diagnosis, management, and treatment of cardiac arrhythmias. Furthermore,…”
Get full text

Pharmacological and simulated exercise cardiac stress tests produce different ischemic signatures in high-resolution experimental mapping studies by Zenger, Brian, Good, Wilson W., Bergquist, Jake A., Rupp, Lindsay C., Perez, Maura, Stoddard, Gregory J., Sharma, Vikas, MacLeod, Rob S.

“…Test the hypothesis that exercise and pharmacological cardiac stressors create different electrical ischemic signatures. Current clinical stress tests for…”
Get full text

Performance of off-the-shelf machine learning architectures and biases in low left ventricular ejection fraction detection by Bergquist, Jake A., Zenger, Brian, Brundage, James, MacLeod, Rob S., Bunch, T. Jared, Shah, Rashmee, Ye, Xiangyang, Lyons, Ann, Torre, Michael, Ranjan, Ravi, Tasdizen, Tolga, Steinberg, Benjamin A.

“…Artificial intelligence–machine learning (AI-ML) has demonstrated the ability to extract clinically useful information from electrocardiograms (ECGs) not…”
Get full text

Quantifying the spatiotemporal influence of acute myocardial ischemia on volumetric conduction velocity by Good, Wilson W., Zenger, Brian, Bergquist, Jake A., Rupp, Lindsay C., Gillette, Karli K., Gsell, Matthias A.F., Plank, Gernot, MacLeod, Rob S.

“…Acute myocardial ischemia occurs when coronary perfusion to the heart is inadequate, which can perturb the highly organized electrical activation of the heart…”
Get full text

Uncertainty Quantification of Fiber Orientation and Epicardial Activation by Rupp, Lindsay C, Busatto, Anna, Bergquist, Jake A, Gillette, Karli, Narayan, Akil, Plank, Gernot, MacLeod, Rob S

“…Predictive models and simulations of cardiac function require accurate representations of anatomy, often to the scale of local myocardial fiber structure…”
Get full text

Comparison of Machine Learning Detection of Low Left Ventricular Ejection Fraction Using Individual ECG Leads by Bergquist, Jake A, Zenger, Brian, Brundage, James, MacLeod, Rob S, Shah, Rashmee, Ye, Xiangyang, Lyones, Ann, Ranjan, Ravi, Tasdizen, Tolga, Bunch, T Jared, Steinberg, Benjamin A

“…The 12-lead electrocardiogram (ECG) is the most common front-line diagnosis tool for assessing cardiovascular health, yet traditional ECG analysis cannot…”
Get full text