Search Results - "Bergonzi, Celine"
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Identification of Cellular Protein Targets of a Half-Sandwich Iridium(III) Complex Reveals Its Dual Mechanism of Action via Both Electrophilic and Oxidative Stresses
Published in Journal of medicinal chemistry (25-04-2024)“…Identification of intracellular targets of anticancer drug candidates provides key information on their mechanism of action. Exploiting the ability of the…”
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Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties
Published in Scientific reports (26-07-2018)“…Quorum quenching lactonases are enzymes that are capable of disrupting bacterial signaling based on acyl homoserine lactones (AHL) via their enzymatic…”
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Evaluation of biological and enzymatic quorum quencher coating additives to reduce biocorrosion of steel
Published in PloS one (16-05-2019)“…Microbial colonization can be detrimental to the integrity of metal surfaces and lead to microbiologically influenced corrosion (MIC). Biocorrosion is a…”
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Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase
Published in Scientific reports (01-12-2017)“…The redesign of enzyme active sites to alter their function or specificity is a difficult yet appealing challenge. Here we used a structure-based design…”
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Correction: Evaluation of biological and enzymatic quorum quencher coating additives to reduce biocorrosion of steel
Published in PloS one (10-06-2021)Get full text
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Signal Disruption Leads to Changes in Bacterial Community Population
Published in Frontiers in microbiology (29-03-2019)“…The disruption of bacterial signaling (quorum quenching) has been proven to be an innovative approach to influence the behavior of bacteria. In particular,…”
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Crystal structure of the phosphate-binding protein (PBP-1) of an ABC-type phosphate transporter from Clostridium perfringens
Published in Scientific reports (16-10-2014)“…Phosphate limitation is an important environmental stress that affects the metabolism of various organisms and, in particular, can trigger the virulence of…”
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Corrigendum: Signal Disruption Leads to Changes in Bacterial Community Population
Published in Frontiers in microbiology (10-05-2021)Get full text
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Field testing of an enzymatic quorum quencher coating additive to reduce biocorrosion of steel
Published in Microbiology spectrum (01-10-2023)“…ABSTRACT Microbial colonization can be detrimental to the integrity of metal surfaces and lead to microbiologically influenced corrosion. Biocorrosion is a…”
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Catalytic Redundancies and Conformational Plasticity Drives Selectivity and Promiscuity in Quorum Quenching Lactonases
Published in JACS Au (23-09-2024)“…Several enzymes from the metallo-β-lactamase-like family of lactonases (MLLs) degrade N-acyl L-homoserine lactones (AHLs). They play a role in a microbial…”
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Changes in Active Site Loop Conformation Relate to the Transition toward a Novel Enzymatic Activity
Published in JACS Au (27-05-2024)“…Enzymatic promiscuity, the ability of enzymes to catalyze multiple, distinct chemical reactions, has been well documented and is hypothesized to be a major…”
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The Structural Determinants Accounting for the Broad Substrate Specificity of the Quorum Quenching Lactonase GcL
Published in Chembiochem : a European journal of chemical biology (15-07-2019)“…Quorum quenching lactonases are enzymes capable of hydrolyzing lactones, including N‐acyl homoserine lactones (AHLs). AHLs are molecules known as signals in…”
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The quorum-quenching lactonase from Geobacillus caldoxylosilyticus: purification, characterization, crystallization and crystallographic analysis
Published in Acta crystallographica. Section F, Structural biology communications (01-09-2016)“…Lactonases are enzymes that are capable of hydrolyzing various lactones such as aliphatic lactones or acyl‐homoserine lactones (AHLs), with the latter being…”
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The quorum‐quenching lactonase from Alicyclobacter acidoterrestris: purification, kinetic characterization, crystallization and crystallographic analysis
Published in Acta crystallographica. Section F, Structural biology communications (01-08-2017)“…Lactonases comprise a class of enzymes that hydrolyze lactones, including acyl‐homoserine lactones (AHLs); the latter are used as chemical signaling molecules…”
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Correction: Evaluation of biological and enzymatic quorum quencher coating additives to reduce biocorrosion of steel
Published in PloS one (01-01-2021)“…[This corrects the article DOI: 10.1371/journal.pone.0217059.]…”
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