Search Results - "Bergmeier, S"
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P0026 Novel quinuclidinone derivative induced apoptosis in human MCF-7 breast cancer cells by targeting p53
Published in European journal of cancer (1990) (01-05-2014)“…Background Identification of agents that are non-toxic but that can delay onset and/or progression of breast cancer is highly desirable. Methods In this study,…”
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Complementing aculiferan mitogenomics: comparative characterization of mitochondrial genomes of Solenogastres (Mollusca, Aplacophora)
Published in BMC ecology and evolution (18-10-2024)“…With the advances in high-throughput sequencing and bioinformatic pipelines, mitochondrial genomes have become increasingly popular for phylogenetic analyses…”
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Factors that influence T box riboswitch efficacy and tRNA affinity
Published in Bioorganic & medicinal chemistry (01-09-2015)“…[Display omitted] The T box riboswitch is an intriguing potential target for antibacterial drug discovery. Found primarily in Gram-positive bacteria, the…”
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Abyssal Solenogastres (Mollusca, Aplacophora) from the Northwest Pacific: Scratching the Surface of Deep-Sea Diversity Using Integrative Taxonomy
Published in Frontiers in Marine Science (14-12-2017)“…Solenogastres (Aplacophora) is a small clade of marine, shell-less worm-molluscs with close to 300 valid species. Their distribution ranges across all oceans,…”
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Anisotropy studies of tRNA-T box antiterminator RNA complex in the presence of 1,4-disubstituted 1,2,3-triazoles
Published in Bioorganic & medicinal chemistry letters (01-12-2011)“…The binding of tRNA to the T box antiterminator RNA element is a critical component of the T box riboswitch mechanism that regulates essential genes in many…”
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Of basins, plains, and trenches: Systematics and distribution of Solenogastres (Mollusca, Aplacophora) in the Northwest Pacific
Published in Progress in oceanography (01-11-2019)“…•First records of Solenogastres from the hadal zone (>6000 m).•First phylogeny of Northwest Pacific Solenogastres reveals conflict with traditional…”
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Characterization of a 1,4-disubstituted 1,2,3-triazole binding to T box antiterminator RNA
Published in Bioorganic & medicinal chemistry (01-02-2012)“…The T box riboswitch regulates the transcription of many bacterial genes by structurally responding to cognate non-aminoacylated (uncharged) tRNA. The…”
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Lost in a taxonomic Bermuda Triangle: comparative 3D-microanatomy of cryptic mesopsammic Solenogastres (Mollusca)
Published in Organisms diversity & evolution (01-09-2016)“…Solenogastres (Mollusca) have a quite uniform bodyplan and an evolutionary history with few shifts out of their deep-water habitat and beyond their epibenthic…”
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Phylogenomic reconstruction of Solenogastres (Mollusca, Aplacophora) informs hypotheses on body size evolution
Published in Molecular phylogenetics and evolution (01-05-2024)“…[Display omitted] •Body size highly dynamic over solenogaster evolution between meio-, macro- and megafaunal size.•Maximum likelihood and Bayesian inference…”
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First Use of the Molecular Adsorbent Recirculating System Technique on Patients with Hypoxic Liver Failure After Cardiogenic Shock
Published in ASAIO journal (1992) (01-07-2004)“…The Molecular Adsorbent Recirculating System (MARS) has been proven to prolong survival in patients with hepatorenal syndrome. MARS is a modified dialysis that…”
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Structure–activity studies with ring E analogues of methyllycaconitine. Synthesis and evaluation of enantiopure isomers of selective antagonist at the α3 nicotinic receptor
Published in European journal of medicinal chemistry (01-06-2002)“…The four diastereomers 4a– d of methyllycaconitine (MLA) analogue 3 (R=(CH 2) 3Ph, R′=CH 3) have been synthesized in enantiomerically pure form by coupling…”
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Crystal Structure of a Conformation-selective Casein Kinase-1 Inhibitor
Published in The Journal of biological chemistry (30-06-2000)“…Members of the casein kinase-1 family of protein kinases play an essential role in cell regulation and disease pathogenesis. Unlike most protein kinases, they…”
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Ring E analogs of methyllycaconitine (MLA) as novel nicotinic antagonists
Published in Bioorganic & medicinal chemistry letters (02-08-1999)“…We have prepared ring E analogs of the diterpenoid alkaloid methyllycaconitine. These compounds have been assayed for nicotinic activity and were found to act…”
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THE SYNTHESIS OF SUCCINIC ACIDS AND DERIVATIVES. A REVIEW
Published in Organic preparations and procedures international (01-08-2002)Get full text
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Selective Removal of an N-BOC Protecting Group in the Presence of a tert-Butyl Ester and Other Acid-Sensitive Groups
Published in Journal of organic chemistry (01-06-1994)Get full text
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Anti-Inflammatory and Therapeutic Effects of a Novel Small-Molecule Inhibitor of Inflammation in a Male C57BL/6J Mouse Model of Obesity-Induced NAFLD/MAFLD
Published in Journal of inflammation research (01-01-2023)“…Non-alcoholic fatty liver disease (NAFLD), recently renamed metabolic (dysfunction) associated fatty liver disease (MAFLD), is the most common chronic liver…”
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Synthesis of oligo(5-aminopentanoic acid)-nucleobases (APN): potential antisense agents
Published in Bioorganic & medicinal chemistry letters (16-12-1997)“…Oligomers of 5-amino pentanoic acid nucleobases have been prepared for use as antisense agents. The synthesis of the 5′-end starter unit and the 3′-end monomer…”
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Synthesis of (-)-slaframine and related indolizidines
Published in Journal of organic chemistry (01-07-1992)Get full text
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