Search Results - "Bergmayr, Christian"
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Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species
Published in Science signaling (05-12-2017)“…Oxytocin and vasopressin mediate various physiological functions that are important for osmoregulation, reproduction, cardiovascular function, social behavior,…”
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Treprostinil reduces endothelial damage in murine sinusoidal obstruction syndrome
Published in Journal of molecular medicine (Berlin, Germany) (01-02-2019)“…Sinusoidal obstruction syndrome (SOS) is a major complication after hematopoietic stem cell transplantation and belongs to a group of diseases increasingly…”
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Recruitment of a Cytoplasmic Chaperone Relay by the A2A Adenosine Receptor
Published in The Journal of biological chemistry (04-10-2013)“…The A2A receptor is known to accumulate in the endoplasmic reticulum. Results: Mass spectrometry identified molecular chaperones (HSP90 and HSP70) bound to the…”
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Insights into the molecular evolution of oxytocin receptor ligand binding
Published in Biochemical Society transactions (01-02-2013)“…The design and development of selective ligands for the human OT (oxytocin) and AVP (arginine vasopressin) receptors is a big challenge since the different…”
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Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin
Published in Chemical science (Cambridge) (25-03-2021)“…Vasopressin (VP) and oxytocin (OT) are cyclic neuropeptides that regulate fundamental physiological functions via four G protein-coupled receptors, V 1a R, V…”
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Researcher of the Month
Published in Wiener Klinische Wochenschrift (01-10-2014)Get full text
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Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation
Published in Molecular pharmacology (01-06-2016)“…Activation of Gs-coupled receptors enhances engraftment of hematopoietic stem and progenitor cells (HSPCs). We tested the hypothesis that treprostinil, a…”
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MUV Researcher of the Month, October 2014
Published in Wiener Klinische Wochenschrift (01-10-2014)Get full text
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The interactome of the A2A adenosine receptor in vitro and in vivo
Published in BMC pharmacology (16-11-2010)“…Materials and methods To verify these interactions in vivo and to identify new interacting proteins of the A2A adenosine receptor we chose a two-step…”
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Pharmacological stimulation of murine and human hematopoetic stem cells
Published in BMC pharmacology & toxicology (17-09-2012)“…Doc number: A67…”
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Treprostinil stimulates the engraftment of haematopoetic stem cells
Published in BMC pharmacology (05-09-2011)Get full text
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The folding interactome of GPCRs
Published in BMC pharmacology (05-09-2011)Get full text
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