Search Results - "Bergmann, Timothy J."

Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D’Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

“…The endoplasmic reticulum (ER) is a site of protein biogenesis in eukaryotic cells. Perturbing ER homeostasis activates stress programs collectively called the…”
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Deep learning approach for quantification of organelles and misfolded polypeptide delivery within degradative compartments by Morone, Diego, Marazza, Alessandro, Bergmann, Timothy J., Molinari, Maurizio

“…LysoQuant is a deep learning approach to segmentation and classification of fluorescent images capturing cargo delivery within endolysosomes for clearance. It…”
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Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors? by Bergmann, Timothy J., Fumagalli, Fiorenza, Loi, Marisa, Molinari, Maurizio

“…Amplification of the candidate oncogene TLOC1/SEC62 in tumors correlates with reduced patient survival. The recently reported role of SEC62 as an autophagy…”
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ER‐to‐lysosome‐associated degradation of proteasome‐resistant ATZ polymers occurs via receptor‐mediated vesicular transport by Fregno, Ilaria, Fasana, Elisa, Bergmann, Timothy J, Raimondi, Andrea, Loi, Marisa, Soldà, Tatiana, Galli, Carmela, D'Antuono, Rocco, Morone, Diego, Danieli, Alberto, Paganetti, Paolo, van Anken, Eelco, Molinari, Maurizio

“…Maintenance of cellular proteostasis relies on efficient clearance of defective gene products. For misfolded secretory proteins, this involves dislocation from…”
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Three branches to rule them all? UPR signalling in response to chemically versus misfolded proteins‐induced ER stress by Bergmann, Timothy J., Molinari, Maurizio

“…Study of the unfolded protein responses (UPR) is mainly addressed by challenging eukaryotic cells with chemical compounds that impair calcium, redox or glycan…”
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Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides by Bergmann, Timothy J., Fregno, Ilaria, Fumagalli, Fiorenza, Rinaldi, Andrea, Bertoni, Francesco, Boersema, Paul J., Picotti, Paola, Molinari, Maurizio

“…The stress sensors ATF6, IRE1, and PERK monitor deviations from homeostatic conditions in the endoplasmic reticulum (ER), a protein biogenesis compartment of…”
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Correction: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D'Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

“…Nature Cell Biology 18, 1173–1184 (2016); published online 17 October 2016; corrected after print 18 November 2016. In the version of this Article originally…”
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Erratum: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J., Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D'Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

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Deep learning approach for quantification of organelles and misfolded polypeptides delivery within degradative compartments by Morone, Diego, Marazza, Alessandro, Bergmann, Timothy J, Molinari, Maurizio

“…Endolysosomal compartments maintain cellular fitness by clearing from cells dysfunctional organelles and proteins. Modulation of their activity offers…”
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Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery by Fumagalli, Fiorenza, Noack, Julia, Bergmann, Timothy J, Cebollero, Eduardo, Pisoni, Giorgia Brambilla, Fasana, Elisa, Fregno, Ilaria, Galli, Carmela, Loi, Marisa, Soldà, Tatiana, D'Antuono, Rocco, Raimondi, Andrea, Jung, Martin, Melnyk, Armin, Schorr, Stefan, Schreiber, Anne, Simonelli, Luca, Varani, Luca, Wilson-Zbinden, Caroline, Zerbe, Oliver, Hofmann, Kay, Peter, Matthias, Quadroni, Manfredo, Zimmermann, Richard, Molinari, Maurizio

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