Search Results - "Bergman, RN"

Minimal model: perspective from 2005 by Bergman, Richard N

“…The minimal model was proposed over 25 years ago. Despite (or because of) its simplicity it continues to be used today - both as a clinical tool and an…”
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Accurate assessment of β-cell function: The hyperbolic correction by BERGMAN, Richard N, ADER, Marilyn, HUECKING, Katrin, VAN CITTERS, Gregg

“…Only in the last decade did modeling studies predict, and knockout experiments confirm, that type 2 diabetes is a "2-hit" disease in which insulin resistance…”
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Atypical antipsychotics and glucose homeostasis by BERGMAN, Richard N, ADER, Marilyn

“…Persistent reports have linked atypical antipsychotics with diabetes, yet causative mechanisms responsible for this linkage are unclear. Goals of this review…”
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Free Fatty Acids and Pathogenesis of Type 2 Diabetes Mellitus by Bergman, Richard N, Ader, Marilyn

“…Plasma free fatty acids (FFA) might mediate the insulin resistance and impaired glucose tolerance associated with central obesity. Central adipocytes are…”
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Quantitative estimation of insulin sensitivity by Bergman, R N, Ider, Y Z, Bowden, C R, Cobelli, C

“…We have evaluated the feasibility of using a mathematical model of glucose disappearance to estimate insulin sensitivity. Glucose was injected into conscious…”
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Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance by Kabir, Morvarid, Catalano, Karyn J, Ananthnarayan, Suchitra, Kim, Stella P, Van Citters, Gregg W, Dea, Melvin K, Bergman, Richard N

“…The mechanism by which increased central adiposity causes hepatic insulin resistance is unclear. The "portal hypothesis" implicates increased lipolytic…”
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Evidence of CB1-Receptor Antagonism in Fat-Fed Dogs Promoting Beiging of Adipose Tissue Mainly via Activation of Sarco/Endoplasmic Reticulum Ca2+ ATPase 2b and Ryanodine Receptor 2 by PASZKIEWICZ, REBECCA L., BERGMAN, RICHARD N., RICHEY, JOYCE M., IYER, MALINI S., WOOLCOTT, ORISON O., KOLKA, CATHRYN M., CLEGG, DEBORAH, KABIR, MORVARID

“…We have previously demonstrated that 16 weeks following exposure to a high fat diet (HFD), dogs treated with the CB1-receptor antagonist (Rimonabant (RIM))…”
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Effects of Exercise Training on Glucose Homeostasis by Boulé, Normand G., Weisnagel, S. John, Lakka, Timo A., Tremblay, Angelo, Bergman, Richard N., Rankinen, Tuomo, Leon, Arthur S., Skinner, James S., Wilmore, Jack H., Rao, D.C., Bouchard, Claude

“…Effects of Exercise Training on Glucose Homeostasis The HERITAGE Family Study Normand G. Boulé , MA 1 , S. John Weisnagel , MD 1 2 , Timo A. Lakka , MD, PHD 3…”
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Insulin sensitivity, Insulin secretion, and abdominal fat: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study by WAGENKNECHT, Lynne E, LANGEFELD, Carl D, SCHERZINGER, Ann L, NORRIS, Jill M, HAFFNER, Steven M, SAAD, Mohammed F, BERGMAN, Richard N

“…The relationship between insulin sensitivity and overall obesity is well established. However, there remains debate as to which of the fat depots, visceral…”
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Metabolic Dysregulation With Atypical Antipsychotics Occurs in the Absence of Underlying Disease A Placebo-Controlled Study of Olanzapine and Risperidone in Dogs by ADER, Marilyn, KIM, Stella P, CATALANO, Karyn J, IONUT, Viorica, HUCKING, Katrin, RICHEY, Joyce M, KABIR, Morvarid, BERGMAN, Richard N

“…Metabolic Dysregulation With Atypical Antipsychotics Occurs in the Absence of Underlying Disease A Placebo-Controlled Study of Olanzapine and Risperidone in…”
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Impaired Glucose Tolerance and Reduced β-Cell Function in Overweight Latino Children with a Positive Family History for Type 2 Diabetes by Goran, Michael I., Bergman, Richard N., Avila, Quintilia, Watkins, Michael, Ball, Geoff D. C., Shaibi, Gabriel Q., Weigensberg, Marc J., Cruz, Martha L.

“…The objective of this study was to examine relationships between impaired glucose tolerance (IGT) and body composition and insulin-related phenotypes in 150…”
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Insulin Resistance and Associated Compensatory Responses in African-American and Hispanic Children by GORAN, Michael I, BERGMAN, Richard N, CRUZ, Martha L, WATANABE, Richard

“…Insulin Resistance and Associated Compensatory Responses in African-American and Hispanic Children Michael I. Goran , PHD , Richard N. Bergman , PHD , Martha…”
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Primacy of Hepatic Insulin Resistance in the Development of the Metabolic Syndrome Induced by an Isocaloric Moderate-Fat Diet in the Dog by KIM, Stella P, ELLMERER, Martin, VAN CITTERS, Gregg W, BERGMAN, Richard N

“…Primacy of Hepatic Insulin Resistance in the Development of the Metabolic Syndrome Induced by an Isocaloric Moderate-Fat Diet in the Dog Stella P. Kim , Martin…”
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The evolution of β-cell dysfunction and insulin resistance in type 2 diabetes by Bergman, R. N., Finegood, D. T., Kahn, S. E.

“…Insulin resistance and β‐cell dysfunction have important roles in the pathogenesis and evolution of type 2 diabetes. The development of precise methods to…”
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Increased susceptibility to insulin resistance associated with abdominal obesity in aging rats by Catalano, K.J, Bergman, R.N, Ader, M

“…Objective: Recent data have suggested that the insulin resistance observed with aging may be more related to adiposity than aging per se. We asked whether the…”
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Genetic Variation Near the Hepatocyte Nuclear Factor-4α Gene Predicts Susceptibility to Type 2 Diabetes by SILANDER, Kaisa, MOHLKE, Karen L, CHINES, Peter S, ERDOS, Michael R, NARISU, Narisu, CONNEELY, Karen N, CHUN LI, FINGERLIN, Tasha E, DHANJAL, Sharanjeet K, VALLE, Timo T, BERGMAN, Richard N, TUOMILEHTO, Jaakko, SCOTT, Laura J, WATANABE, Richard M, BOEHNKE, Michael, COLLINS, Francis S, PECK, Erin C, HOLLSTEIN, Pablo, SKOL, Andrew D, JACKSON, Anne U, DELOUKAS, Panagiotis, HUNT, Sarah, STAVRIDES, George

“…Genetic Variation Near the Hepatocyte Nuclear Factor-4α Gene Predicts Susceptibility to Type 2 Diabetes Kaisa Silander 1 , Karen L. Mohlke 1 , Laura J. Scott 2…”
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Neuropeptides and neurotrophin receptor mRNAs primary sensory neurons of aged rats by Bergman, Esbjörn, Johnson, Hans, Zhang, Xu, Hökfelt, Tomas, Ulfhake, Brun

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Non-esterified fatty acids and the liver : why is insulin secreted into the portal vein? by BERGMAN, R. N

“…Insulin control of glucose output is a major mechanism by which appropriate amounts of glucose are produced to supply energy to the central nervous system,…”
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Insulin Resistance and Hypertension: The Insulin Resistance Atherosclerosis Study by Saad, Mohammed F, Rewers, Marian, Selby, Joseph, Howard, George, Jinagouda, Sujata, Fahmi, Salwa, Zaccaro, Dan, Bergman, Richard N, Savage, Peter J, Haffner, Steven M

“…The association between insulin resistance and insulinemia and hypertension is controversial. We examined the relation between insulin resistance and…”
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Macrophage Gene Expression in Adipose Tissue is Associated with Insulin Sensitivity and Serum Lipid Levels Independent of Obesity by Ahlin, S., Sjöholm, K., Jacobson, P., Andersson‐Assarsson, J.C., Walley, A., Tordjman, J., Poitou, C., Prifti, E., Jansson, P.‐A., Borén, J., Sjöström, L., Froguel, P., Bergman, R.N., Carlsson, L.M.S., Olsson, B., Svensson, P.‐A.

“…Objective: Obesity is linked to both increased metabolic disturbances and increased adipose tissue macrophage infiltration. However, whether macrophage…”
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