Search Results - "Bergman, Marie‐Louise"
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Signatures in SARS-CoV-2 spike protein conferring escape to neutralizing antibodies
Published in PLoS pathogens (05-08-2021)“…Understanding SARS-CoV-2 evolution and host immunity is critical to control COVID-19 pandemics. At the core is an arms-race between SARS-CoV-2 antibody and…”
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Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions
Published in European journal of immunology (01-04-2009)“…Induction of Forkhead-box p3 (Foxp3) expression in developing T cells upon peptide-MHC encountering has been proposed to define a lineage of committed Treg…”
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Production of high‐quality SARS‐CoV‐2 antigens: Impact of bioprocess and storage on glycosylation, biophysical attributes, and ELISA serologic tests performance
Published in Biotechnology and bioengineering (01-06-2021)“…Serological assays are valuable tools to study SARS‐CoV‐2 spread and, importantly, to identify individuals that were already infected and would be potentially…”
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The first steps of adaptation of Escherichia coli to the gut are dominated by soft sweeps
Published in PLoS genetics (01-03-2014)“…The accumulation of adaptive mutations is essential for survival in novel environments. However, in clonal populations with a high mutational supply, the power…”
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Population homogeneity for the antibody response to COVID-19 BNT162b2/Comirnaty vaccine is only reached after the second dose across all adult age ranges
Published in Nature communications (10-01-2022)“…While mRNA vaccines are administrated worldwide in an effort to contain the COVID-19 pandemic, the heterogeneity of the humoral immune response they induce at…”
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Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-2013)“…Most Forkhead box P3 ⁺ (Foxp3 ⁺) CD4 regulatory T cell (Treg) precursors are newly formed thymocytes that acquire Foxp3 expression on antigen encounter in the…”
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The multifaceted Foxp3fgfp allele enhances spontaneous and therapeutic immune surveillance of cancer in mice
Published in European journal of immunology (01-03-2020)“…It is well established that therapeutic impairment of Foxp3+ Treg in mice and humans favors immune rejection of solid tumors. Less explored is the impact Foxp3…”
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Control of Disease Tolerance to Malaria by Nitric Oxide and Carbon Monoxide
Published in Cell reports (Cambridge) (10-07-2014)“…Nitric oxide (NO) and carbon monoxide (CO) are gasotransmitters that suppress the development of severe forms of malaria associated with Plasmodium infection…”
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Tolerogenic insulin peptide therapy precipitates type 1 diabetes
Published in The Journal of experimental medicine (03-07-2017)“…Daniel et al. (https://doi.org/10.1084/jem.20110574) have previously published in JEM a study on the preventive effect of tolerogenic vaccination with a strong…”
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When three is not a crowd: a Crossregulation Model of the dynamics and repertoire selection of regulatory CD4⁺ T cells
Published in Immunological reviews (01-04-2007)“…Regulatory CD4⁺ T cells, enriched in the CD25 pool of healthy individuals, mediate natural tolerance and prevent autoimmune diseases. Despite their fundamental…”
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Longitudinal Analysis of Antibody Responses to the mRNA BNT162b2 Vaccine in Patients Undergoing Maintenance Hemodialysis: A 6-Month Follow-Up
Published in Frontiers in medicine (24-12-2021)“…Patients on hemodialysis (HD) are at higher risk for COVID-19, overall are poor responders to vaccines, and were prioritized in the Portuguese vaccination…”
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Prevention of Diabetes in Nonobese Diabetic Mice Mediated by CD1d-Restricted Nonclassical NKT Cells
Published in The Journal of immunology (1950) (01-09-2004)“…A role for regulatory lymphocytes has been demonstrated in the pathogenesis of type 1 diabetes in the NOD mouse but the nature of these cells is debated…”
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Interruption of Thymic Activity in Adult Mice Improves Responses to Tumor Immunotherapy
Published in The Journal of immunology (1950) (01-03-2021)“…The thymus produces precursors of both conventional T cells (Tconv; also known as effector T cells) and regulatory T cells (Treg) whose interactions prevent…”
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Ferritin heavy chain supports stability and function of the regulatory T cell lineage
Published in The EMBO journal (16-04-2024)“…Regulatory T (TREG) cells develop via a program orchestrated by the transcription factor forkhead box protein P3 (FOXP3). Maintenance of the TREG cell lineage…”
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The multifaceted Foxp3 fgfp allele enhances spontaneous and therapeutic immune surveillance of cancer in mice
Published in European journal of immunology (01-03-2020)“…It is well established that therapeutic impairment of Foxp3 Treg in mice and humans favors immune rejection of solid tumors. Less explored is the impact Foxp3…”
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Defective Induction of CTLA-4 in the NOD Mouse Is Controlled by the NOD Allele of Idd3/IL-2 and a Novel Locus (Ctex) Telomeric on Chromosome 1
Published in Diabetes (New York, N.Y.) (01-02-2006)“…Defective Induction of CTLA-4 in the NOD Mouse Is Controlled by the NOD Allele of Idd3/IL-2 and a Novel Locus ( Ctex ) Telomeric on Chromosome 1 Marie Lundholm…”
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Apoptosis Resistance of Nonobese Diabetic Peripheral Lymphocytes Linked to the Idd5 Diabetes Susceptibility Region
Published in Proceedings of the National Academy of Sciences - PNAS (05-08-1997)“…Defects in lymphocyte apoptosis may lead to autoimmune disorders and contribute to the pathogenesis of type 1 diabetes. Lymphocytes of nonobese diabetic (NOD)…”
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Diabetes Protection and Restoration of Thymocyte Apoptosis in NOD Idd6 Congenic Strains
Published in Diabetes (New York, N.Y.) (01-07-2003)“…Diabetes Protection and Restoration of Thymocyte Apoptosis in NOD Idd6 Congenic Strains Marie-Louise Bergman 1 , Nadia Duarte 1 2 , Susana Campino 2 , Marie…”
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Cutting edge: Intrathymic differentiation of adaptive Foxp3+ regulatory T cells upon peripheral proinflammatory immunization
Published in The Journal of immunology (1950) (01-10-2010)“…Thymocytes differentiate into CD4(+) Foxp3(+) regulatory T cells (T(R)) upon interaction between their TCR and peptide-MHC II complexes locally expressed in…”
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The enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11
Published in The Journal of immunology (1950) (15-04-2005)“…The NOD mouse is an important experimental model for human type 1 diabetes. T cells are central to NOD pathogenesis, and their function in the autoimmune…”
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