Search Results - "Bergles, DE"

Developmental origin of oligodendrocytes determines their function in the adult brain by Foerster, Sarah, Floriddia, Elisa M., van Bruggen, David, Kukanja, Petra, Hervé, Bastien, Cheng, Shangli, Kim, Eosu, Phillips, Benjamin U., Heath, Christopher J., Tripathi, Richa B., Call, Cody, Bartels, Theresa, Ridley, Katherine, Neumann, Björn, López-Cruz, Laura, Crawford, Abbe H., Lynch, Cian J., Serrano, Manuel, Saksida, Lisa, Rowitch, David H., Möbius, Wiebke, Nave, Klaus-Armin, Rasband, Matthew N., Bergles, Dwight E., Kessaris, Nicoletta, Richardson, William D., Bussey, Timothy J., Zhao, Chao, Castelo-Branco, Gonçalo, Franklin, Robin J. M.

“…In the mouse embryonic forebrain, developmentally distinct oligodendrocyte progenitor cell populations and their progeny, oligodendrocytes, emerge from three…”
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β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression by Toan, Shuy Vang, Fisher, Paul B, Gupta, Pankaj, Bruijn, Lucie I, Jin, Lin, Vidensky, Svetlana, Rothstein, Jeffrey D, Regan, Melissa R, Patel, Sarjubhai, Bergles, Dwight E, Chung, Dorothy S, Haenggeli, Christine, Dykes Hoberg, Margaret, Su, Zao-zhong, Huang, Yanhua H

“…Glutamate is the principal excitatory neurotransmitter in the nervous system. Inactivation of synaptic glutamate is handled by the glutamate transporter GLT1…”
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Excitatory actions of norepinephrine on multiple classes of hippocampal CA1 interneurons by Bergles, DE, Doze, VA, Madison, DV, Smith, SJ

“…Norepinephrine (NE) causes an increase in the frequency of inhibitory postsynaptic potentials in CA1 pyramidal neurons in vitro. The possibility that this…”
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Glutamate transporters bring competition to the synapse by Huang, Yanhua H, Bergles, Dwight E

“…Glutamate transporters (GluTs) prevent the accumulation of glutamate and influence the occupancy of receptors at synapses. The ability of extrasynaptic NMDA…”
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Synaptic signaling between GABAergic interneurons and oligodendrocyte precursor cells in the hippocampus by Bergles, Dwight E, Lin, Shih-chun

“…Oligodendrocyte precursor cells (OPCs) express receptors for many neurotransmitters, but the mechanisms responsible for their activation are poorly understood…”
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Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus by Bergles, Dwight E, Roberts, J. David B, Somogyi, Peter, Jahr, Craig E

“…Fast excitatory neurotransmission in the central nervous system occurs at specialized synaptic junctions between neurons, where a high concentration of…”
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Climbing Fiber Innervation of NG2-Expressing Glia in the Mammalian Cerebellum by Lin, Shih-chun, Huck, Jojanneke H.J., Roberts, J. David B., Macklin, Wendy B., Somogyi, Peter, Bergles, Dwight E.

“…The molecular layer of the cerebellar cortex is populated by glial progenitors that express ionotropic glutamate receptors and extend numerous processes among…”
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Astrocyte Glutamate Transporters Regulate Metabotropic Glutamate Receptor-Mediated Excitation of Hippocampal Interneurons by Huang, Yanhua H, Sinha, Saurabh R, Tanaka, Kohichi, Rothstein, Jeffrey D, Bergles, Dwight E

“…Clearance of extracellular glutamate is essential for limiting the activity of metabotropic glutamate receptors (mGluRs) at excitatory synapses; however, the…”
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Synaptic activation of glutamate transporters in hippocampal astrocytes by Bergles, D E, Jahr, C E

“…Glutamate transporters in the CNS are expressed in neurons and glia and mediate high affinity, electrogenic uptake of extracellular glutamate. Although glia…”
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Comparison of Coupled and Uncoupled Currents during Glutamate Uptake by GLT-1 Transporters by Bergles, Dwight E, Tzingounis, Anastassios V, Jahr, Craig E

“…The transport of glutamate across the plasma membrane is coupled to the movement of cations (Na+, K+, and H+) that are necessary for glutamate uptake and…”
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Synaptic signaling between neurons and glia by Lin, Shih-Chun, Bergles, Dwight E.

“…Rapid signaling between vertebrate neurons occurs primarily at synapses, intercellular junctions where quantal release of neurotransmitter triggers rapid…”
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Mossy fiber growth and synaptogenesis in rat hippocampal slices in vitro by Dailey, ME, Buchanan, J, Bergles, DE, Smith, SJ

“…Hippocampal slices from early postnatal rat were used to study mossy fiber (MF) growth and synaptogenesis. The ability of MFs to form new giant synapses within…”
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Clearance of glutamate inside the synapse and beyond by Bergles, Dwight E, Diamond, Jeffrey S, Jahr, Craig E

“…The heated debate over the level of postsynaptic receptor occupancy by transmitter has not been extinguished — indeed, new evidence is fanning the flames…”
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Glial Contribution to Glutamate Uptake at Schaffer Collateral-Commissural Synapses in the Hippocampus by Bergles, Dwight E, Jahr, Craig E

“…Astrocytes in the hippocampus express high-affinity glutamate transporters that are important for lowering the concentration of extracellular glutamate after…”
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Climbing Fiber Activation of EAAT4 Transporters and Kainate Receptors in Cerebellar Purkinje Cells by Huang, Yanhua H, Dykes-Hoberg, Margaret, Tanaka, Kohichi, Rothstein, Jeffrey D, Bergles, Dwight E

“…Cerebellar Purkinje cells (PCs) express two glutamate transporters, EAAC1 (EAAT3) and EAAT4; however, their relative contribution to the uptake of glutamate at…”
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Glutamate Transporter Currents in Bergmann Glial Cells Follow the Time Course of Extrasynaptic Glutamate by Bergles, D E, Dzubay, J A, Jahr, C E

“…Glutamate transporters in the central nervous system are expressed in both neurons and glia, they mediate high affinity, electrogenic uptake of glutamate, and…”
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Shape-shifting at a cerebellar synapse allows submillisecond signaling by Bergles, Dwight E

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Glutamate Release Monitored with Astrocyte Transporter Currents during LTP by Diamond, Jeffrey S, Bergles, Dwight E, Jahr, Craig E

“…Long-term potentiation (LTP) of synaptic transmission in the CA1 region of the hippocampus is thought to result from either increased transmitter release,…”
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Synthesis and Characterization of 4-Methoxy-7-nitroindolinyl-d-aspartate, a Caged Compound for Selective Activation of Glutamate Transporters and N-Methyl-d-aspartate Receptors in Brain Tissue by Huang, Yanhua H, Sinha, Saurabh R, Fedoryak, Olesya D, Ellis-Davies, Graham C. R, Bergles, Dwight E

“…The d-isomer of aspartate is efficiently transported by high-affinity Na+/K+-dependent glutamate transporters and is an effective ligand of…”
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Ncm- d-aspartate: A novel caged d-aspartate suitable for activation of glutamate transporters and N-methyl- d-aspartate (NMDA) receptors in brain tissue by Huang, Yanhua H., Muralidharan, Sukumaran, Sinha, Saurabh R., Kao, Joseph P.Y., Bergles, Dwight E.

“…The d-isomer of aspartate is both a substrate for glutamate transporters and an agonist of N-methyl- d-aspartate (NMDA) receptors. To monitor the behavior of…”
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