Search Results - "Bergholtz, Sarah E"

A chemoproteomic portrait of the oncometabolite fumarate by Kulkarni, Rhushikesh A., Bak, Daniel W., Wei, Darmood, Bergholtz, Sarah E., Briney, Chloe A., Shrimp, Jonathan H., Alpsoy, Aktan, Thorpe, Abigail L., Bavari, Arissa E., Crooks, Daniel R., Levy, Michaella, Florens, Laurence, Washburn, Michael P., Frizzell, Norma, Dykhuizen, Emily C., Weerapana, Eranthie, Linehan, W. Marston, Meier, Jordan L.

“…Hereditary cancer disorders often provide an important window into novel mechanisms supporting tumor growth. Understanding these mechanisms thus represents a…”
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A Mixed-Methods Study of Clinicians’ Attitudes Toward Pathology Explanation Clinics by Bergholtz, Sarah E, Kurnot, Sophia R, DeJonckheere, Melissa, Hawley, Sarah T, Owens, Scott R, Lapedis, Cathryn J

“…Abstract Objectives To characterize the attitudes of treating clinicians toward pathology explanation clinics (PECs). Methods Clinicians from a tertiary care…”
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A longitudinal mixed-methods study of pathology explanation clinics in patients with newly diagnosed localized prostate cancer by Bergholtz, Sarah E, Kurnot, Sophia R, Elahi, Esha, DeJonckheere, Melissa, Hawley, Sarah T, Owens, Scott R, Salami, Simpa, Morgan, Todd M, Lapedis, Cathryn J

“…To characterize the role of pathology explanation clinics (PECs) in prostate cancer care and determine their impact on patients, urologic oncologists, and…”
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Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite by Perez, Minervo, Bak, Daniel W., Bergholtz, Sarah E., Crooks, Daniel R., Arimilli, Bhargav Srinivas, Yang, Youfeng, Weerapana, Eranthie, Linehan, W. Marston, Meier, Jordan L.

“…An important context in which metabolism influences tumorigenesis is the genetic cancer syndrome hereditary leiomyomatosis and renal cell carcinoma (HLRCC), a…”
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Synthesis and Evaluation of a Stable Isostere of Malonyllysine by Jing, Yihang, Bergholtz, Sarah E., Omole, Anthony, Kulkarni, Rhushi A., Zengeya, Thomas T., Yoo, Euna, Meier, Jordan L.

“…Lysine malonylation is a recently characterized post‐translational modification involved in the regulation of energy metabolism and gene expression. One unique…”
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A Systems Chemoproteomic Analysis of Acyl-CoA/Protein Interaction Networks by Levy, Michaella J, Montgomery, David C, Sardiu, Mihaela E, Montano, Jose L, Bergholtz, Sarah E, Nance, Kellie D, Thorpe, Abigail L, Fox, Stephen D, Lin, Qishan, Andresson, Thorkell, Florens, Laurence, Washburn, Michael P, Meier, Jordan L

“…Acyl-coenzyme A (CoA)/protein interactions are essential for life. Despite this importance, their global scope and selectivity remains undefined. Here, we…”
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An Oncometabolite Isomer Rapidly Induces a Pathophysiological Protein Modification by Bergholtz, Sarah E, Briney, Chloe A, Najera, Susana S, Perez, Minervo, Linehan, W. Marston, Meier, Jordan L

“…Metabolites regulate protein function via covalent and noncovalent interactions. However, manipulating these interactions in living cells remains a major…”
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Photoinducible Oncometabolite Detection by Kulkarni, Rhushikesh A., Briney, Chloe A., Crooks, Daniel R., Bergholtz, Sarah E., Mushti, Chandrasekhar, Lockett, Stephen J., Lane, Andrew N., Fan, Teresa W.‐M., Swenson, Rolf E., Marston Linehan, W., Meier, Jordan L.

“…Dysregulated metabolism can fuel cancer by altering the production of bioenergetic building blocks and directly stimulating oncogenic gene‐expression programs…”
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Abstract 2759: Chemoproteomic profiling of the oncometabolite fumarate by Bergholtz, Sarah E., Briney, Chloe A., Kulkarni, Rhushikesh A., Wei, David, Bak, Daniel W., Shrimp, Jonathan H., Weerapana, Eranthie, Linehan, W. Marston, Meier, Jordan L.

“…Abstract Dysregulated metabolism is a feature of many diseases, including cancer. In addition to providing energy and building blocks to growing cells, altered…”
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Cover Feature: Photoinducible Oncometabolite Detection (ChemBioChem 3/2019) by Kulkarni, Rhushikesh A., Briney, Chloe A., Crooks, Daniel R., Bergholtz, Sarah E., Mushti, Chandrasekhar, Lockett, Stephen J., Lane, Andrew N., Fan, Teresa W.‐M., Swenson, Rolf E., Marston Linehan, W., Meier, Jordan L.

“…The cover feature picture shows an optical illusion that can be viewed either as a white vase or the outline of two faces. By analogy, the nitrileimine–alkene…”
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