Search Results - "Bergeron, Angela"

Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c by Edelstein, Leonard C, Simon, Lukas M, Montoya, Raúl Teruel, Holinstat, Michael, Chen, Edward S, Bergeron, Angela, Kong, Xianguo, Nagalla, Srikanth, Mohandas, Narla, Cohen, David E, Dong, Jing-fei, Shaw, Chad, Bray, Paul F

“…In exploring the possibility that racial differences in platelet function might exist, Paul Bray and his colleagues report that platelets from blacks have a…”
Get full text

Unlocking Aspirin's Chemopreventive Activity: Role of Irreversibly Inhibiting Platelet Cyclooxygenase-1 by Lichtenberger, Lenard M, Fang, Dexing, Bick, Roger J, Poindexter, Brian J, Phan, Tri, Bergeron, Angela L, Pradhan, Subhashree, Dial, Elizabeth J, Vijayan, K Vinod

“…The mechanism by which aspirin consumption is linked to significant reductions in the incidence of multiple forms of cancer and metastatic spread to distant…”
Get full text

Aggregometry detects platelet hyperreactivity in healthy individuals by Yee, Donald L., Sun, Carol W., Bergeron, Angela L., Dong, Jing-fei, Bray, Paul F.

“…Aggregometry is widely used to assess platelet function, but its use in identifying platelet hyperreactivity is poorly defined. We studied platelet aggregation…”
Get full text

Flow cytometric measurement of microparticles: Pitfalls and protocol modifications by Shah, Mona D., Bergeron, Angela L., Dong, Jing-Fei, López, José A.

“…Upon activation, many cells shed components of their plasma membranes as microparticles. Depending on the methods of preparation and analyses, microparticle…”
Get full text

Association between cell-derived microparticles and adverse events in patients with nonpulsatile left ventricular assist devices by Nascimbene, Angelo, MD, Hernandez, Ruben, MD, George, Joggy K., MD, Parker, Anita, RN, Bergeron, Angela L., BS, Pradhan, Subhashree, PhD, Vijayan, K. Vinod, PhD, Civitello, Andrew, MD, Simpson, Leo, MD, Nawrot, Maria, PhD, Lee, Vei-Vei, MS, Mallidi, Hari R., MD, Delgado, Reynolds M., MD, Dong, Jing Fei, MD, Frazier, O.H., MD

“…Background Continuous-flow left ventricular assist devices (LVADs) expose blood cells to high shear stress, potentially resulting in the production of…”
Get full text

Mechanical activation of a multimeric adhesive protein through domain conformational change by Wijeratne, Sithara S, Botello, Eric, Yeh, Hui-Chun, Zhou, Zhou, Bergeron, Angela L, Frey, Eric W, Patel, Jay M, Nolasco, Leticia, Turner, Nancy A, Moake, Joel L, Dong, Jing-fei, Kiang, Ching-Hwa

“…The mechanical force-induced activation of the adhesive protein von Willebrand factor (VWF), which experiences high hydrodynamic forces, is essential in…”
Get full text

Magnesium maintains endothelial integrity, up-regulates proteolysis of ultra-large von Willebrand factor, and reduces platelet aggregation under flow conditions by Dong, Jing-fei, Cruz, Miguel A, Aboulfatova, Khatira, Martin, Cecilia, Choi, Hiuwan, Bergeron, Angela L, Martini, Sheryl R, Kroll, Michael H, Kent, Thomas A

“…Mg (++) regulates endothelial functions and has anti-inflammatory effects. Its effects on thrombosis have been demonstrated, but the mechanism remains poorly…”
Get more information

Acquired ADAMTS-13 deficiency in pediatric patients with severe sepsis by Nguyen, Trung C, Liu, Anne, Liu, Li, Ball, Chalmette, Choi, Hiuwan, May, William S, Aboulfatova, Khatira, Bergeron, Angela L, Dong, Jing-fei

“…From the Department of Pediatrics (TCN, KA); Thrombosis Research Section, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA (AL, LL, CB,…”
Get full text

Heterogeneous effects of tissue inhibitors of matrix metalloproteinases on cardiac fibroblasts by Lovelock, Joshua D, Baker, Andrew H, Gao, Feng, Dong, Jing-Fei, Bergeron, Angela L, McPheat, Willie, Sivasubramanian, Natarajan, Mann, Douglas L

“…The balance between matrix metalloproteinases (MMPs) and their natural inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), plays a critical role…”
Get more information

Protein Phosphatase 2A Negatively Regulates Integrin αIIbβ3 Signaling by Gushiken, Francisca C., Patel, Vimal, Liu, Yan, Pradhan, Subhashree, Bergeron, Angela L., Peng, Yuandong, Vijayan, K. Vinod

“…Integrin αIIbβ3 activation is critical for platelet physiology and is controlled by signal transduction through kinases and phosphatases. Compared with…”
Get full text

Platelet aggregation and activation under complex patterns of shear stress by Zhang, Jian-ning, Bergeron, Angela L, Yu, Qinghua, Sun, Carol, McIntire, Larry V, López, José A, Dong, Jing-fei

“…Arterial stenosis results in a complex pattern of blood flow containing an extremely fast flow in the throat of stenosis and a post-stenosis low flow. The fast…”
Get more information

Duration of exposure to high fluid shear stress is critical in shear-induced platelet activation-aggregation by Zhang, Jian-ning, Bergeron, Angela L, Yu, Qinghua, Sun, Carol, McBride, Latresha, Bray, Paul F, Dong, Jing-fei

“…Platelet functions are increasingly measured under flow conditions to account for blood hydrodynamic effects. Typically, these studies involve exposing…”
Get more information

Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling by Gushiken, Francisca C, Patel, Vimal, Liu, Yan, Pradhan, Subhashree, Bergeron, Angela L, Peng, Yuandong, Vijayan, K Vinod

“…Integrin alpha(IIb)beta(3) activation is critical for platelet physiology and is controlled by signal transduction through kinases and phosphatases. Compared…”
Get full text

Gender-dependent up-regulation of ADAMTS-13 in mice with obesity and hypercholesterolemia by Liu, Mine Y, Zhou, Zhou, Ma, Ruidong, Tao, Zhenyin, Choi, Huiwan, Bergeron, Angela L, Wu, Huaizhu, Dong, Jing-fei

Get full text

Proteomic analysis of resting and thrombin-stimulated platelets reveals the translocation and functional relevance of HIP-55 in platelets by Tucker, Katherine L, Kaiser, William J, Bergeron, Angela L, Hu, Hongbo, Dong, Jing-fei, Tan, Tse-Hua, Gibbins, Jonathan M

“…The platelet surface is a dynamic interface that changes rapidly in response to stimuli to co-ordinate the formation of thrombi at sites of vascular injury…”
Get full text

Increased platelet sensitivity among individuals with aspirin resistance - platelet aggregation to submaximal concentration of arachidonic acid predicts response to antiplatelet therapy by Guthikonda, Sasidhar, Mangalpally, Kirankumar, Vaduganathan, Muthiah, Patel, Rajnikant, Delao, Timothy, Bergeron, Angela L, Dong, Jing-Fei, Lev, Eli I, Kleiman, Neal S

“…Aspirin 'resistance' (AR) is a phenomenon of uncertain etiology describing decreased platelet inhibition by aspirin. We studied whether (i) platelets in AR…”
Get more information

ASSOCIATIONS BETWEEN LIPOPROTEIN CHOLESTEROL FRACTIONS AND MEASURES OF PLATELET AGGREGATION IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE by Virani, Salim S, Nambi, Vijay, Athamneh, Husam, Kumar, Anirudh, Bergeron, Angela L, Saunders, Justin, Yang, Eric, Bechara, Carlos, Morrisett, Joel D, Chen, Changyi, Lin, Peter H, Lumsden, Alan B, Dong, Jing-fei, Ballantyne, Christie M

Get full text

Differences in responses of platelets to fluid shear stress in patients with peripheral artery disease (PAD) and coronary artery disease (CAD) by Nambi, Vijay, Kimball, Kay T., Bray, Paul F., Bergeron, Angela L., Johnson, Shawna L., Morrisett, Joel D., Chen, Changyi, Lin, Peter H., Lumsden, Alan B., Ballantyne, Christie M., Dong, Jing-fei

“…Information on differences in platelet function between patients with peripheral arterial disease (PAD) and patients with coronary artery disease (CAD) is…”
Get full text

Enhanced platelet adhesion and aggregation by endothelial cell-derived unusually large multimers of von Willebrand factor by Kumar, R Anand, Moake, Joel L, Nolasco, Leticia, Bergeron, Angela L, Sun, Carol, Dong, Jing-fei, McIntire, Larry V

“…Endothelial cells synthesize and secrete von Willebrand factor (VWF) multimers, including unusually large forms (ULVWF), which are usually cleaved into smaller…”
Get more information

Platelet reactivity among Asian Indians and Caucasians by Patel, Rajnikant T., Lev, Eli I., Vaduganathan, Muthiah, Guthikonda, Sasidhar, Bergeron, Angela, Maresh, Kelly, Dong, Jing-Fei, Kleiman, Neal S.

“…Asian Indians are reported to have higher mortality and morbidity from coronary artery disease (CAD) than other ethnic groups. This variation in events cannot…”
Get full text