Search Results - "Berger, Martin"

Tumour budding in solid cancers by Lugli, Alessandro, Zlobec, Inti, Berger, Martin D., Kirsch, Richard, Nagtegaal, Iris D.

“…Tumour budding is an emerging prognostic biomarker in colorectal cancer (CRC) and other solid cancers. Tumour buds are usually defined as isolated single…”
Get full text

CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation – A target for novel cancer therapy by Tokunaga, Ryuma, Zhang, Wu, Naseem, Madiha, Puccini, Alberto, Berger, Martin D, Soni, Shivani, McSkane, Michelle, Baba, Hideo, Lenz, Heinz-Josef

“…•Chemokines induce chemotaxis, promote differentiation of immune cells, and cause tissue extravasation.•The CXCL9, -10, -11/CXCR3 axis regulates immune cell…”
Get full text

Tumour budding and its clinical implications in gastrointestinal cancers by Zlobec, Inti, Berger, Martin D., Lugli, Alessandro

“…Tumour budding in colorectal cancer has become an important prognostic factor. Represented by single cells or small tumour cell clusters at the invasion front…”
Get full text

B cell and B cell-related pathways for novel cancer treatments by Tokunaga, Ryuma, Naseem, Madiha, Lo, Jae Ho, Battaglin, Francesca, Soni, Shivani, Puccini, Alberto, Berger, Martin D., Zhang, Wu, Baba, Hideo, Lenz, Heinz-Josef

“…•B cells secrete immunoglobulins, promote T cell response, kill cancer cells directly.•B cell and B cell-related pathways play key roles in activating local…”
Get full text

Outlooks on Epstein-Barr virus associated gastric cancer by Naseem, Madiha, Barzi, Afsaneh, Brezden-Masley, Christine, Puccini, Alberto, Berger, Martin D., Tokunaga, Ryuma, Battaglin, Francesca, Soni, Shivani, McSkane, Michelle, Zhang, Wu, Lenz, Heinz-Josef

“…•Approximately 10% of all gastric cancers are related to EBV infection.•EBV associated gastric cancers have a distinct molecular and clinical profile.•These…”
Get full text

Oxidised Low-Density Lipoprotein-Induced Platelet Hyperactivity—Receptors and Signalling Mechanisms by Berger, Martin, Naseem, Khalid M.

“…Dyslipidaemia leads to proatherogenic oxidative lipid stress that promotes vascular inflammation and thrombosis, the pathologies that underpin myocardial…”
Get full text

Conditional knockdown of integrin beta-3 reveals its involvement in osteolytic and soft tissue lesions of breast cancer skeletal metastasis by Kovacheva, Marineta, Zepp, Michael, Berger, Stefan, Berger, Martin R.

“…Integrin β3 (ITGB3) is probably related to skeletal metastasis, which is the most frequent complication in breast cancer progression. We aimed to define its…”
Get full text

Validation of the International Tumor Budding Consensus Conference 2016 recommendations on tumor budding in stage I-IV colorectal cancer by Dawson, Heather, Galuppini, Francesca, Träger, Peter, Berger, Martin D., Studer, Peter, Brügger, Lukas, Zlobec, Inti, Inderbitzin, Daniel, Lugli, Alessandro

“…Tumor budding is a robust prognostic parameter in colorectal cancer and can be used as an additional factor to guide patient management. Although backed by…”
Get full text

Conditional Knockdown of Osteopontin Inhibits Breast Cancer Skeletal Metastasis by Kovacheva, Marineta, Zepp, Michael, Schraad, Muriel, Berger, Stefan, Berger, Martin R

“…High osteopontin (OPN) expression is linked to breast cancer bone metastasis. In this study we modulated osteopontin levels conditionally and investigated any…”
Get full text

Characteristics and burden of acute COVID-19 and long-COVID: Demographic, physical, mental health, and economic perspectives by Leitner, Manuel, Pötz, Gloria, Berger, Martin, Fellner, Maria, Spat, Stephan, Koini, Marisa

“…COVID-19 infection and its associated consequence, known as long-COVID, lead to a significant burden on the global healthcare system and limitations in…”
Get full text

Preservation of Epstein–Barr virus status and mismatch repair protein status along the metastatic course of gastric cancer by Dislich, Bastian, Blaser, Nicola, Berger, Martin D, Gloor, Beat, Langer, Rupert

“…Aims Epstein–Barr virus (EBV) in‐situ hybridisation and mismatch repair (MMR) protein immunohistochemistry identifies two subgroups of gastric cancer (GC) with…”
Get full text

Sniffer dogs can identify lung cancer patients from breath and urine samples by Feil, Charlotte, Staib, Frank, Berger, Martin R, Stein, Thorsten, Schmidtmann, Irene, Forster, Andreas, Schimanski, Carl C

“…Lung cancer is the most common oncological cause of death in the Western world. Early diagnosis is critical for successful treatment. However, no effective…”
Get full text

Biomarkers in Metastatic Colorectal Cancer: Status Quo and Future Perspective by Puccini, Alberto, Seeber, Andreas, Berger, Martin D

“…Colorectal cancer (CRC) is the third most frequent cancer worldwide, and its incidence is steadily increasing. During the last two decades, a tremendous…”
Get full text

Comprehensive Genomic Profiling of Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs) by Puccini, Alberto, Poorman, Kelsey, Salem, Mohamed E, Soldato, Davide, Seeber, Andreas, Goldberg, Richard M, Shields, Anthony F, Xiu, Joanne, Battaglin, Francesca, Berger, Martin D, Tokunaga, Ryuma, Naseem, Madiha, Barzi, Afsaneh, Iqbal, Syma, Zhang, Wu, Soni, Shivani, Hwang, Jimmy J, Philip, Philip A, Sciallero, Stefania, Korn, W Michael, Marshall, John L, Lenz, Heinz-Josef

“…GEP-NENs are rare malignancies with increasing incidence. Their molecular characteristics are still undefined. We explored the underlying biology of GEP-NENs…”
Get full text

The CCR5 antagonist maraviroc causes remission of pancreatic cancer liver metastasis in nude rats based on cell cycle inhibition and apoptosis induction by Huang, Huiying, Zepp, Michael, Georges, Rania B., Jarahian, Mostafa, Kazemi, Maryam, Eyol, Ergül, Berger, Martin R.

“…Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease, and novel therapeutic strategies are urgently needed. Recently, expression of the C–C…”
Get full text

The impact of ARID1A mutation on molecular characteristics in colorectal cancer by Tokunaga, Ryuma, Xiu, Joanne, Goldberg, Richard M., Philip, Philip A., Seeber, Andreas, Battaglin, Francesca, Arai, Hiroyuki, Lo, Jae Ho, Naseem, Madiha, Puccini, Alberto, Berger, Martin D., Soni, Shivani, Zhang, Wu, Chen, Sting, Hwang, Jimmy J., Shields, Anthony F., Marshall, John L., Baba, Hideo, Korn, W.Michael, Lenz, Heinz-Josef

“…ARID1A is a key subunit of the SWItch/Sucrose Non-Fermentable (SWI/SNF) complex which regulates dynamic repositioning of nucleosomes to repair DNA damage. Only…”
Get full text

Multiple Facets of Autophagy and the Emerging Role of Alkylphosphocholines as Autophagy Modulators by Kaleağasıoğlu, Ferda, Ali, Doaa M, Berger, Martin R

“…Autophagy is a highly conserved multistep process and functions as passage for degrading and recycling protein aggregates and defective organelles in…”
Get full text

A subgroup of lactosyl-Sepharose binding proteins requires calcium for affinity and galactose for anti-proliferation by Sagini, Micah N., Hotz-Wagenblatt, Agnes, Berger, Martin R.

“…Lactosyl-Sepharose binding proteins (LSBPs) were recently described in human pancreatic ductal adenocarcinoma (PDAC) Suit2-007 cells regarding their…”
Get full text

Stromal PD-1/PD-L1 Expression Predicts Outcome in Colon Cancer Patients by Wyss, Jacqueline, Dislich, Bastian, Koelzer, Viktor H., Galván, José A., Dawson, Heather, Hädrich, Marion, Inderbitzin, Daniel, Lugli, Alessandro, Zlobec, Inti, Berger, Martin D.

“…The programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) axis plays an important role in controlling immune suppression by down-regulating T…”
Get full text

CCR5 blockage by maraviroc: a potential therapeutic option for metastatic breast cancer by Pervaiz, Asim, Zepp, Michael, Mahmood, Saqib, Ali, Doaa Mohamed, Berger, Martin R., Adwan, Hassan

“…Purpose Bone metastasis is observed in up to 70% of breast cancer patients. The currently available treatment options are palliative in nature. Chemokine…”
Get full text