Search Results - "Berger, Mark J"

M-CAP eliminates a majority of variants of uncertain significance in clinical exomes at high sensitivity by Jagadeesh, Karthik A, Wenger, Aaron M, Berger, Mark J, Guturu, Harendra, Stenson, Peter D, Cooper, David N, Bernstein, Jonathan A, Bejerano, Gill

“…Gill Bejerano and colleagues present M-CAP, a classifier that estimates variant pathogenicity in clinical exome data sets. They show that M-CAP outperforms…”
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Single-cell transcriptional diversity is a hallmark of developmental potential by Gulati, Gunsagar S, Sikandar, Shaheen S, Wesche, Daniel J, Manjunath, Anoop, Bharadwaj, Anjan, Berger, Mark J, Ilagan, Francisco, Kuo, Angera H, Hsieh, Robert W, Cai, Shang, Zabala, Maider, Scheeren, Ferenc A, Lobo, Neethan A, Qian, Dalong, Yu, Feiqiao B, Dirbas, Frederick M, Clarke, Michael F, Newman, Aaron M

“…Single-cell RNA sequencing (scRNA-seq) is a powerful approach for reconstructing cellular differentiation trajectories. However, inferring both the state and…”
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Independent erosion of conserved transcription factor binding sites points to shared hindlimb, vision and external testes loss in different mammals by Berger, Mark J, Wenger, Aaron M, Guturu, Harendra, Bejerano, Gill

“…Abstract Genetic variation in cis-regulatory elements is thought to be a major driving force in morphological and physiological changes. However, identifying…”
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Allele-specific expression reveals genetic drivers of tissue regeneration in mice by Mack, Katya L., Talbott, Heather E., Griffin, Michelle F., Parker, Jennifer B.L., Guardino, Nicholas J., Spielman, Amanda F., Davitt, Michael F., Mascharak, Shamik, Downer, Mauricio, Morgan, Annah, Valencia, Caleb, Akras, Deena, Berger, Mark J., Wan, Derrick C., Fraser, Hunter B., Longaker, Michael T.

“…In adult mammals, skin wounds typically heal by scarring rather than through regeneration. In contrast, “super-healer” Murphy Roths Large (MRL) mice have the…”
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Color Data v2: a user-friendly, open-access database with hereditary cancer and hereditary cardiovascular conditions datasets by Berger, Mark J, Williams, Hannah E, Barrett, Ryan, Zimmer, Anjali D, McKennon, Wendy, Hong, Huy, Ginsberg, Jeremy, Zhou, Alicia Y, Neben, Cynthia L

“…Abstract Publicly available genetic databases promote data sharing and fuel scientific discoveries for the prevention, treatment and management of disease. In…”
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