Search Results - "Berger, Marc"

A Review of Gaucher Disease Pathophysiology, Clinical Presentation and Treatments by Stirnemann, Jérôme, Belmatoug, Nadia, Camou, Fabrice, Serratrice, Christine, Froissart, Roseline, Caillaud, Catherine, Levade, Thierry, Astudillo, Leonardo, Serratrice, Jacques, Brassier, Anaïs, Rose, Christian, Billette de Villemeur, Thierry, Berger, Marc G

“…Gaucher disease (GD, ORPHA355) is a rare, autosomal recessive genetic disorder. It is caused by a deficiency of the lysosomal enzyme, glucocerebrosidase, which…”
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How Can We Make More Rapid Progress in the Leveraging of Real-World Evidence by Regulatory Decision Makers? by Berger, Marc L., Crown, William

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Acute mountain sickness: Do different time courses point to different pathophysiological mechanisms? by Berger, Marc M, Sareban, Mahdi, Bärtsch, Peter

“…Acute mountain sickness (AMS) is a syndrome of nonspecific symptoms (i.e., headache, anorexia, nausea, vomiting, dizziness, and fatigue) that may develop in…”
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Impact of Mitochondrial Ca2+-Sensitive Potassium (mBKCa) Channels in Sildenafil-Induced Cardioprotection in Rats by Behmenburg, Friederike, Dorsch, Marianne, Huhn, Ragnar, Mally, David, Heinen, André, Hollmann, Markus W, Berger, Marc M

“…Mitochondrial large-conductance Ca2+-sensitive potassium (mBKCa) channels are involved in myocardial ischemic preconditioning. Their role in sildenafil-induced…”
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Impaired Cytotoxic CD8 + T Cell Response in Elderly COVID-19 Patients by Westmeier, Jaana, Paniskaki, Krystallenia, Karaköse, Zehra, Werner, Tanja, Sutter, Kathrin, Dolff, Sebastian, Overbeck, Marvin, Limmer, Andreas, Liu, Jia, Zheng, Xin, Brenner, Thorsten, Berger, Marc M, Witzke, Oliver, Trilling, Mirko, Lu, Mengji, Yang, Dongliang, Babel, Nina, Westhoff, Timm, Dittmer, Ulf, Zelinskyy, Gennadiy

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces a T cell response that most likely contributes to virus control in COVID-19…”
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Discontinuation of tyrosine kinase inhibitor therapy in chronic myeloid leukaemia (EURO-SKI): a prespecified interim analysis of a prospective, multicentre, non-randomised, trial by Saussele, Susanne, Richter, Johan, Guilhot, Joelle, Gruber, Franz X, Hjorth-Hansen, Henrik, Almeida, Antonio, Janssen, Jeroen J W M, Mayer, Jiri, Koskenvesa, Perttu, Panayiotidis, Panayiotis, Olsson-Strömberg, Ulla, Martinez-Lopez, Joaquin, Rousselot, Philippe, Vestergaard, Hanne, Ehrencrona, Hans, Kairisto, Veli, Machová Poláková, Katerina, Müller, Martin C, Mustjoki, Satu, Berger, Marc G, Fabarius, Alice, Hofmann, Wolf-Karsten, Hochhaus, Andreas, Pfirrmann, Markus, Mahon, Francois-Xavier, Ossenkoppele, Gert, Pagoni, Maria N., Söderlund, Stina, Escoffre-Barbe, Martine, Etienne, Gabriel, Dengler, Jolanta, Huguet, Francoise, von Bubnoff, Nikolas, Klamova, Hana, Faber, Edgar, Guilhot, Francois, Lotfi, Kourosh, Rea, Delphine, Brümmendorf, Tim H., de Greef, Gorgine E., Stenke, Leif, Nicolini, Franck E., Legros, Laurence, Burchert, Andreas, Voglova, Jaroslava, Charbonnier, Aude, Gyan, Emmanuel, Kunzmann, Volker, Westerweel, Peter E.

“…Tyrosine kinase inhibitors (TKIs) have improved the survival of patients with chronic myeloid leukaemia. Many patients have deep molecular responses, a…”
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Good practices for real‐world data studies of treatment and/or comparative effectiveness: Recommendations from the joint ISPOR‐ISPE Special Task Force on real‐world evidence in health care decision making by Berger, Marc L., Sox, Harold, Willke, Richard J., Brixner, Diana L., Eichler, Hans‐Georg, Goettsch, Wim, Madigan, David, Makady, Amr, Schneeweiss, Sebastian, Tarricone, Rosanna, Wang, Shirley V., Watkins, John, Daniel Mullins, C.

“…Purpose Real‐world evidence (RWE) includes data from retrospective or prospective observational studies and observational registries and provides insights…”
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Longer treatment duration and history of osteoarticular symptoms predispose to tyrosine kinase inhibitor withdrawal syndrome by Berger, Marc G., Pereira, Bruno, Rousselot, Philippe, Cony‐Makhoul, Pascale, Gardembas, Martine, Legros, Laurence, Escoffre‐Barbe, Martine, Nicolini, Franck‐Emmanuel, Saugues, Sandrine, Lambert, Céline, Réa, Delphine, Guerci‐Bresler, Agnès, Giraudier, Stéphane, Guilhot, Joëlle, Saussele, Susanne, Mahon, François‐Xavier

“…Summary The effectiveness of tyrosine kinase inhibitors (TKIs) has made it possible to consider treatment discontinuation in chronic myeloid leukaemia (CML)…”
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Good Research Practices for Comparative Effectiveness Research: Defining, Reporting and Interpreting Nonrandomized Studies of Treatment Effects Using Secondary Data Sources: The ISPOR Good Research Practices for Retrospective Database Analysis Task Force Report—Part I by Berger, Marc L., MD, Mamdani, Muhammad, PharmD, MA, MPH, Atkins, David, MD, MPH, Johnson, Michael L., PhD

“…ABSTRACT Objectives Health insurers, physicians, and patients worldwide need information on the comparative effectiveness and safety of prescription drugs in…”
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Good Practices for Real‐World Data Studies of Treatment and/or Comparative Effectiveness: Recommendations from the Joint ISPOR‐ISPE Special Task Force on Real‐World Evidence in Health Care Decision Making by Berger, Marc L., Sox, Harold, Willke, Richard J., Brixner, Diana L., Eichler, Hans‐Georg, Goettsch, Wim, Madigan, David, Makady, Amr, Schneeweiss, Sebastian, Tarricone, Rosanna, Wang, Shirley V., Watkins, John, Mullins, C. Daniel

“…Real‐world evidence (RWE) includes data from retrospective or prospective observational studies and observational registries and provides insights beyond those…”
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Toward Facilitated Self-Service in Health Care by Asch, David A, Nicholson, Sean, Berger, Marc L

“…Strategies for transforming health care using alternative payment systems, patient-centered care, and technology have had limited success. In other industries,…”
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Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0 by Wang, Shirley V., Schneeweiss, Sebastian, Berger, Marc L., Brown, Jeffrey, Vries, Frank, Douglas, Ian, Gagne, Joshua J., Gini, Rosa, Klungel, Olaf, Mullins, C. Daniel, Nguyen, Michael D., Rassen, Jeremy A., Smeeth, Liam, Sturkenboom, Miriam, Berger, Marc L., Brown, Jeffrey, Vries, Frank, Douglas, Ian, Gagne, Joshua J., Gini, Rosa, Klungel, Olaf, Mullins, C. Daniel, Nguyen, Michael D., Rassen, Jeremy A., Smeeth, Liam, Sturkenboom, Miriam, Bate, Andrew, Bourke, Alison, Cadarette, Suzanne, Gerhard, Tobias, Glynn, Robert, Huybrechts, Krista, Kubota, Kiyoshi, Makady, Amr, Nyberg, Fredrik, Ritchey, Mary E., Rothman, Ken, Toh, Sengwee

“…Purpose Defining a study population and creating an analytic dataset from longitudinal healthcare databases involves many decisions. Our objective was to…”
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Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections by Bénard, Alan, Jacobsen, Anne, Brunner, Maximilian, Krautz, Christian, Klösch, Bettina, Swierzy, Izabela, Naschberger, Elisabeth, Podolska, Malgorzata J., Kouhestani, Dina, David, Paul, Birkholz, Torsten, Castellanos, Ixchel, Trufa, Denis, Sirbu, Horia, Vetter, Marcel, Kremer, Andreas E., Hildner, Kai, Hecker, Andreas, Edinger, Fabian, Tenbusch, Matthias, Mühl-Zürbes, Petra, Steinkasserer, Alexander, Richter, Enrico, Streeck, Hendrik, Berger, Marc M., Brenner, Thorsten, Weigand, Markus A., Swirski, Filip K., Schett, Georg, Grützmann, Robert, Weber, Georg F.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide health threat. In a prospective multicentric study, we identify IL-3 as an…”
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DNA Methylation and Intra-Clonal Heterogeneity: The Chronic Myeloid Leukemia Model by Lebecque, Benjamin, Bourgne, Céline, Vidal, Véronique, Berger, Marc G.

“…Chronic Myeloid Leukemia (CML) is a model to investigate the impact of tumor intra-clonal heterogeneity in personalized medicine. Indeed, tyrosine kinase…”
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Differential Inductive Sensing System for Truly Contactless Measuring of Liquids' Electromagnetic Properties in Tubing by Berger, Marc, Zygmanowski, Anne, Zimmermann, Stefan

“…Certain applications require a contactless measurement to eliminate the risk of sensor-induced sample contamination. Examples can be found in chemical process…”
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Relation of corona-specific health literacy to use of and trust in information sources during the COVID-19 pandemic by De Gani, Saskia Maria, Berger, Fabian Marc Pascal, Guggiari, Elena, Jaks, Rebecca

“…COVID-19 has developed into a worldwide pandemic which was accompanied by an «infodemic» consisting of much false and misleading information. To cope with…”
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Flow cytometric analysis of neutrophil myeloperoxidase expression in peripheral blood for ruling out myelodysplastic syndromes: a diagnostic accuracy study by Raskovalova, Tatiana, Berger, Marc G, Jacob, Marie-Christine, Park, Sophie, Campos, Lydia, Aanei, Carmen Mariana, Kasprzak, Julie, Pereira, Bruno, Labarère, José, Cesbron, Jean-Yves, Veyrat-Masson, Richard

“…Suspicion of myelodysplastic syndromes (MDS) is one of the commonest reasons for bone marrow aspirate in elderly patients presenting with persistent peripheral…”
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How Geometry Affects Sensitivity of a Differential Transformer for Contactless Characterization of Liquids by Berger, Marc, Zygmanowski, Anne, Zimmermann, Stefan

“…The electrical and dielectric properties of liquids can be used for sensing. Specific applications, e.g., the continuous in-line monitoring of blood…”
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Accuracy of chitotriosidase activity and CCL18 concentration in assessing type I Gaucher disease severity. A systematic review with meta-analysis of individual participant data by Raskovalova, Tatiana, Deegan, Patrick B, Mistry, Pramod K, Pavlova, Elena, Yang, Ruby, Zimran, Ari, Berger, Juliette, Bourgne, Céline, Pereira, Bruno, Labarère, José, Berger, Marc G

“…Chitotriosidase activity and CCL18 concentration are interchangeably used for monitoring Gaucher disease (GD) activity, together with clinical assessment…”
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The Magnitude and Functionality of SARS-CoV-2 Reactive Cellular and Humoral Immunity in Transplant Population Is Similar to the General Population Despite Immunosuppression by Thieme, Constantin J., Anft, Moritz, Paniskaki, Krystallenia, Blazquez-Navarro, Arturo, Doevelaar, Adrian, Seibert, Felix S., Hoelzer, Bodo, Justine Konik, Margarethe, Meister, Toni L., Pfaender, Stephanie, Steinmann, Eike, Moritz Berger, Marc, Brenner, Thorsten, Kölsch, Uwe, Dolff, Sebastian, Roch, Toralf, Witzke, Oliver, Schenker, Peter, Viebahn, Richard, Stervbo, Ulrik, Westhoff, Timm H., Babel, Nina

“…The ability of transplant (Tx) patients to generate a protective antiviral response under immunosuppression is pivotal in COVID-19 infection. However, analysis…”
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