Search Results - "Bergen, S. E."

Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis by Yoshimi, N, Futamura, T, Bergen, S E, Iwayama, Y, Ishima, T, Sellgren, C, Ekman, C J, Jakobsson, J, Pålsson, E, Kakumoto, K, Ohgi, Y, Yoshikawa, T, Landén, M, Hashimoto, K

“…Although evidence for mitochondrial dysfunction in the pathogenesis of bipolar disorder (BD) has been reported, the precise biological basis remains unknown,…”
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Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder by Bergen, S E, O'Dushlaine, C T, Ripke, S, Lee, P H, Ruderfer, D M, Akterin, S, Moran, J L, Chambert, K D, Handsaker, R E, Backlund, L, Ösby, U, McCarroll, S, Landen, M, Scolnick, E M, Magnusson, P K E, Lichtenstein, P, Hultman, C M, Purcell, S M, Sklar, P, Sullivan, P F

“…Schizophrenia (SCZ) and bipolar disorder (BD) are highly heritable psychiatric disorders with overlapping susceptibility loci and symptomatology. We conducted…”
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A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder by Sellgren, C M, Kegel, M E, Bergen, S E, Ekman, C J, Olsson, S, Larsson, M, Vawter, M P, Backlund, L, Sullivan, P F, Sklar, P, Smoller, J W, Magnusson, P K E, Hultman, C M, Walther-Jallow, L, Svensson, C I, Lichtenstein, P, Schalling, M, Engberg, G, Erhardt, S, Landén, M

“…Elevated cerebrospinal fluid (CSF) levels of the glia-derived N -methyl- D -aspartic acid receptor antagonist kynurenic acid (KYNA) have consistently been…”
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Copy number variation in schizophrenia in Sweden by Szatkiewicz, J P, O'Dushlaine, C, Chen, G, Chambert, K, Moran, J L, Neale, B M, Fromer, M, Ruderfer, D, Akterin, S, Bergen, S E, Kähler, A, Magnusson, P K E, Kim, Y, Crowley, J J, Rees, E, Kirov, G, O'Donovan, M C, Owen, M J, Walters, J, Scolnick, E, Sklar, P, Purcell, S, Hultman, C M, McCarroll, S A, Sullivan, P F

“…Schizophrenia (SCZ) is a highly heritable neuropsychiatric disorder of complex genetic etiology. Previous genome-wide surveys have revealed a greater burden of…”
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Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder by Rueckert, E H, Barker, D, Ruderfer, D, Bergen, S E, O'Dushlaine, C, Luce, C J, Sheridan, S D, Theriault, K M, Chambert, K, Moran, J, Purcell, S M, Madison, J M, Haggarty, S J, Sklar, P

“…Several genome-wide association studies for bipolar disorder (BD) have found a strong association of the Ankyrin 3 ( ANK3 ) gene. This association spans…”
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Prognostic impact of breast cancer subtypes in elderly patients by Bergen, E. S., Tichy, C., Berghoff, A. S., Rudas, M., Dubsky, P., Bago-Horvath, Z., Mader, R. M., Exner, R., Gnant, M., Zielinski, C. C., Steger, G. G., Preusser, M., Bartsch, R.

“…We aimed to analyse the impact of breast cancer (BC) subtypes on the clinical course of disease with special emphasis on the occurrence of brain metastases…”
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Schizophrenia and subsequent neighborhood deprivation: revisiting the social drift hypothesis using population, twin and molecular genetic data by Sariaslan, A, Fazel, S, D'Onofrio, B M, Långström, N, Larsson, H, Bergen, S E, Kuja-Halkola, R, Lichtenstein, P

“…Neighborhood influences in the etiology of schizophrenia have been emphasized in a number of systematic reviews, but causality remains uncertain. To test the…”
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Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility by Li, M, Luo, X-j, Rietschel, M, Lewis, C M, Mattheisen, M, Müller-Myhsok, B, Jamain, S, Leboyer, M, Landén, M, Thompson, P M, Cichon, S, Nöthen, M M, Schulze, T G, Sullivan, P F, Bergen, S E, Donohoe, G, Morris, D W, Hargreaves, A, Gill, M, Corvin, A, Hultman, C, Toga, A W, Shi, L, Lin, Q, Shi, H, Gan, L, Meyer-Lindenberg, A, Czamara, D, Henry, C, Etain, B, Bis, J C, Ikram, M A, Fornage, M, Debette, S, Launer, L J, Seshadri, S, Erk, S, Walter, H, Heinz, A, Bellivier, F, Stein, J L, Medland, S E, Arias Vasquez, A, Hibar, D P, Franke, B, Martin, N G, Wright, M J, Su, B

“…Bipolar disorder (BD) is a polygenic disorder that shares substantial genetic risk factors with major depressive disorder (MDD). Genetic analyses have reported…”
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Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder by Song, J, Bergen, S E, Di Florio, A, Karlsson, R, Charney, A, Ruderfer, D M, Stahl, E A, Chambert, K D, Moran, J L, Gordon-Smith, K, Forty, L, Green, E K, Jones, I, Jones, L, Scolnick, E M, Sklar, P, Smoller, J W, Lichtenstein, P, Hultman, C, Craddock, N, Landén, M

“…This corrects the article DOI: 10.1038/mp.2015.165…”
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Analysis of schizophrenia-related genes and electrophysiological measures reveals ZNF804A association with amplitude of P300b elicited by novel sounds by del Re, E C, Bergen, S E, Mesholam-Gately, R I, Niznikiewicz, M A, Goldstein, J M, Woo, T U, Shenton, M E, Seidman, L J, McCarley, R W, Petryshen, T L

“…Several genes have recently been identified as risk factors for schizophrenia (SZ) by genome-wide association studies (GWAS), including ZNF804A which is…”
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Association study of SNAP25 and schizophrenia in Irish family and case-control samples by Fanous, A.H., Zhao, Z., van den Oord, E.J.C.G., Maher, B.S., Thiselton, D.L., Bergen, S.E., Wormley, B., Bigdeli, T., Amdur, R.L., O'Neill, F.A., Walsh, D., Kendler, K.S., Riley, B.P.

“…SNAP25 occurs on chromosome 20p12.2, which has been linked to schizophrenia in some samples, and recently linked to latent classes of psychotic illness in our…”
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Clinical risk factors for ascites in metastatic pancreatic cancer by Berger, J.M., Alany, A., Puhr, R., Berchtold, L., Friedrich, A., Scheiner, B., Prager, G.W., Berghoff, A.S., Preusser, M., Bergen, E.S.

“…Malignant ascites is common in metastatic pancreatic cancer (mPC) and its management still remains a clinical challenge. Early identification of patients at…”
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Androgen receptor expression in breast cancer brain metastases by Bergen, E.S., Berghoff, A.S.S., Rajky, U., Rudas, M., Bago-Horvath, Z., Exner, R., Dieckmann, K., Widhalm, G., Gnant, M.I., Zielinski, C.C., Steger, G.G., Preusser, M., Bartsch, R.

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Cross‐sex shifts in two brain imaging phenotypes and their relation to polygenic scores for same‐sex sexual behavior: A study of 18,645 individuals from the UK Biobank by Abé, Christoph, Lebedev, Alexander, Zhang, Ruyue, Jonsson, Lina, Bergen, Sarah E., Ingvar, Martin, Landén, Mikael, Rahman, Qazi

“…Genetic and hormonal factors have been suggested to influence human sexual orientation. Previous studied proposed brain differences related to sexual…”
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Association and Familial Coaggregation of Childhood-Onset Type 1 Diabetes With Depression, Anxiety, and Stress-Related Disorders: A Population-Based Cohort Study by Liu, Shengxin, Leone, Marica, Ludvigsson, Jonas F., Lichtenstein, Paul, D’Onofrio, Brian, Svensson, Ann-Marie, Gudbjörnsdottir, Soffia, Bergen, Sarah E., Larsson, Henrik, Kuja-Halkola, Ralf, Butwicka, Agnieszka

“…OBJECTIVE To estimate the association and familial coaggregation of childhood-onset type 1 diabetes with depression, anxiety, and stress-related disorders…”
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Association and familial co-aggregation of type 1 diabetes with depression, anxiety and stress-related disorders: a population-based cohort study by Liu, S., Leone, M., Larsson, Henrik, Lichtenstein, P., D'Onofrio, B. M., Bergen, S. E., Kuja-Halkola, R., Butwicka, A.

“…Background and aims : People with type 1 diabetes are known to be at heightened risk of common mental health problems. However, it remains unknown whether…”
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Prognosticators of survival in patients with metastatic pancreatic cancer and ascites by Berger, Julia M., Alany, Ashly, Berchtold, Luzia, Puhr, Mag. Rainer, Friedrich, Alexander, Scheiner, Bernhard, Prager, Gerald W., Preusser, Matthias, Berghoff, Anna S., Bergen, Elisabeth S.

“…Identification of factors associated with survival after ascites diagnosis in metastatic pancreatic cancer (mPC) patients may guide treatment decisions and…”
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Primary tumor side is associated with prognosis of colorectal cancer patients with brain metastases by Bergen, E.S., Scherleitner, P., Ferreira, P., Kiesel, B., Müller, C., Widhalm, G., Dieckmann, K., Prager, G., Preusser, M., Berghoff, A.S.

“…Brain metastases (BM) are a rare complication in colorectal cancer (CRC) patients and associated with an unfavorable survival prognosis. Primary tumor side…”
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Efficacy and safety of the combination of encorafenib/cetuximab with or without binimetinib in patients with BRAF V600E-mutated metastatic colorectal cancer: an AGEO real-world multicenter study by Gallois, C., Bergen, E.S., Auclin, É., Pernot, S., Higué, J., Trouilloud, I., Touchefeu, Y., Turpin, A., Mazard, T., Sartore-Bianchi, A., Prenen, H., Alberti, A., Pilla, L., Cuissy, S., Wookey, V., Perret, A., Melchior, C., Artru, P., Dubreuil, O., Drouillard, A., Doat, S., Lavolé, J., Basile, D., Perkins, G., Jary, M., Stintzing, S., Ros, J., Tougeron, D., Taieb, J.

“…The combination of encorafenib with cetuximab has become the standard of care in patients with BRAF V600E-mutated metastatic colorectal cancer (mCRC) after a…”
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Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder by Song, J, Bergen, S E, Di Florio, A, Karlsson, R, Charney, A, Ruderfer, D M, Stahl, E A, Chambert, K D, Moran, J L, Gordon-Smith, K, Forty, L, Green, E K, Jones, I, Jones, L, Scolnick, E M, Sklar, P, Smoller, J W, Lichtenstein, P, Hultman, C, Craddock, N, Landén, M, Smoller, Jordan W, Perlis, Roy H, Lee, Phil Hyoun, Castro, Victor M, Hoffnagle, Alison G, Sklar, Pamela, Stahl, Eli A, Purcell, Shaun M, Ruderfer, Douglas M, Charney, Alexander W, Roussos, Panos, Michele Pato, Carlos Pato, Medeiros, Helen, Sobel, Janet, Craddock, Nick, Jones, Ian, Forty, Liz, Florio, Arianna Di, Green, Elaine, Jones, Lisa, Gordon-Smith, Katherine, Landen, Mikael, Hultman, Christina, Jureus, Anders, Bergen, Sarah, McCarroll, Steven, Moran, Jennifer, Chambert, Kimberly, Belliveau, Richard A

“…Lithium is the mainstay prophylactic treatment for bipolar disorder (BD), but treatment response varies considerably across individuals. Patients who respond…”
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