Search Results - "Bergamini, Carlo M."
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Transglutaminases: nature's biological glues
Published in Biochemical journal (01-12-2002)“…Transglutaminases (Tgases) are a widely distributed group of enzymes that catalyse the post-translational modification of proteins by the formation of…”
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Systemic oxidative stress in older patients with mild cognitive impairment or late onset Alzheimer's disease
Published in Current Alzheimer research (01-05-2013)“…A large body of evidences obtained in human and animal brain tissue suggest a role of oxidative stress (OxS) in the pathogenesis of late onset Alzheimer's…”
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3
Association between circulatory levels of adipokines and bone mineral density in postmenopausal women
Published in Menopause (New York, N.Y.) (01-09-2016)“…OBJECTIVE:Epidemiological evidence indicates that excess fat may be beneficial for bone health, offering protective effects against the onset of postmenopausal…”
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Characterization by Gene Expression Analysis of Two Groups of Dopaminergic Cells Isolated from the Mouse Olfactory Bulb
Published in Biology (Basel, Switzerland) (25-02-2023)“…The olfactory bulb (OB) is one of two regions of the mammalian brain which undergo continuous neuronal replacement during adulthood. A significant fraction of…”
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Machine Learning Algorithms Highlight tRNA Information Content and Chargaff’s Second Parity Rule Score as Important Features in Discriminating Probiotics from Non-Probiotics
Published in Biology (Basel, Switzerland) (07-07-2022)“…Probiotic bacteria are microorganisms with beneficial effects on human health and are currently used in numerous food supplements. However, no selection…”
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Inhibition of the lncRNA Coded within Transglutaminase 2 Gene Impacts Several Relevant Networks in MCF-7 Breast Cancer Cells
Published in Non-coding RNA (18-08-2021)“…Long non-coding RNAs are nucleotide molecules that regulate transcription in numerous cellular processes and are related to the occurrence of many diseases,…”
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The Motility and Mesenchymal Features of Breast Cancer Cells Correlate with the Levels and Intracellular Localization of Transglutaminase Type 2
Published in Cells (Basel, Switzerland) (06-11-2021)“…We have investigated motility in breast cancer cell lines in association with the expression of Transglutaminase type 2 (TG2) as well as upon the…”
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Changes in protein expression in two cholangiocarcinoma cell lines undergoing formation of multicellular tumor spheroids in vitro
Published in PloS one (10-03-2015)“…Epithelial-to-Mesenchymal Transition (EMT) is relevant in malignant growth and frequently correlates with worsening disease progression due to its implications…”
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Oxidative damage and the pathogenesis of menopause related disturbances and diseases
Published in Clinical chemistry and laboratory medicine (01-05-2016)“…The postmenopausal phase of life is frequently associated in women with subjective symptoms (e.g. vasomotor) and real diseases (atherosclerosis with coronary…”
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Transglutaminase 2, a double face enzyme
Published in Amino acids (01-03-2017)Get full text
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Oxidative stress and menopause-related hot flashes may be independent events
Published in Taiwanese journal of obstetrics & gynecology (01-06-2015)“…Abstract Objective At present, there is growing demand for alternative, or additional, treatments to hormone replacement therapy for menopause-related hot…”
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Metabolic characterisation of transglutaminase 2 inhibitor effects in breast cancer cell lines
Published in The FEBS journal (01-11-2023)“…Transglutaminase 2 (TG2), which mediates post-translational modifications of multiple intracellular enzymes, is involved in the pathogenesis and progression of…”
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Oxidative balance, homocysteine, and uric acid levels in older patients with Late Onset Alzheimer's Disease or Vascular Dementia
Published in Journal of the neurological sciences (15-02-2014)“…Abstract This study aimed to investigate whether Late Onset Alzheimer's Disease (LOAD) and Vascular Dementia (VAD) might be associated with a distinct profile…”
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Transcriptomics Studies Reveal Functions of Transglutaminase 2 in Breast Cancer Cells Using Membrane Permeable and Impermeable Inhibitors
Published in Journal of molecular biology (15-05-2024)“…[Display omitted] •Transglutaminase 2 displays yet to be defined roles inside and outside the cell.•Membrane permeable and impermeable inhibitors are valid…”
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A long non-coding RNA inside the type 2 transglutaminase gene tightly correlates with the expression of its transcriptional variants
Published in Amino acids (01-04-2018)“…The long non-coding RNAs (lncRNAs) are matter of intense investigation as potential regulators of gene expression. In the case of the transglutaminase 2 gene (…”
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Involvement of non-coding RNAs and transcription factors in the induction of Transglutaminase isoforms by ATRA
Published in Amino acids (01-09-2019)“…The multifunctional protein Transglutaminase type 2, is associated with cancer epithelial mesenchymal transition, invasiveness, stemness and drugs resistance…”
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Body mass index is a major determinant of abdominal fat accumulation in pre-, peri- and post-menopausal women
Published in Gynecological endocrinology (01-01-2009)“…Objective. To investigate the role of menopause, body mass index (BMI) and aging on body fat distribution in women. Design. In this population-based…”
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PON-1 and ferroxidase activities in older patients with mild cognitive impairment, late onset Alzheimer's disease or vascular dementia
Published in Clinical chemistry and laboratory medicine (01-06-2015)“…A large body of evidence suggests that not only cerebral but also systemic oxidative stress (OxS) might be involved in the pathogenesis of late onset…”
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Dysregulation of Transglutaminase type 2 through GATA3 defines aggressiveness and Doxorubicin sensitivity in breast cancer
Published in International journal of biological sciences (2022)“…The role of transglutaminase type 2 in cell physiology is related to protein transamidation and signal transduction (affecting extracellular, intracellular and…”
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Systemic Oxidative Stress and Conversion to Dementia of Elderly Patients with Mild Cognitive Impairment
Published in BioMed research international (01-01-2014)“…Mild cognitive impairment (MCI) is regarded as a prodromal phase of late onset Alzheimer’s disease (LOAD). It has been proposed that oxidative stress (OxS)…”
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