Search Results - "Berezovsky, Artem D."
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Sox2 Promotes Malignancy in Glioblastoma by Regulating Plasticity and Astrocytic Differentiation
Published in Neoplasia (New York, N.Y.) (01-03-2014)“…Abstract The high-mobility group–box transcription factor sex-determining region Y–box 2 (Sox2) is essential for the maintenance of stem cells from early…”
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Identifying conserved molecular targets required for cell migration of glioblastoma cancer stem cells
Published in Cell death & disease (26-02-2020)“…Glioblastoma (GBM) is the most prevalent primary malignant brain tumor and is associated with extensive tumor cell infiltration into the adjacent brain…”
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Optimization of high grade glioma cell culture from surgical specimens for use in clinically relevant animal models and 3D immunochemistry
Published in Journal of visualized experiments (07-01-2014)“…Glioblastomas, the most common and aggressive form of astrocytoma, are refractory to therapy, and molecularly heterogeneous. The ability to establish cell…”
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Abstract 1505: Platelet derived growth factor receptor alpha oncogene dependency in glioblastoma
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Platelet-derived growth factor receptor alpha (PDGFRA) is a ligand-activated receptor tyrosine kinase (RTK) involved in neurodevelopment. In pediatric and…”
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Abstract 3491: Heterogeneous extrachromosomal amplification of mutant PDGFRA is associated with an aggressive phenotype in glioblastoma
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Background & Objective: Receptor tyrosine kinase (RTK) signaling is altered in over 80% of glioblastoma (GBM) cases, frequently through gene amplification…”
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Abstract 3385: Sox2 is necessary for glioblastoma cell plasticity
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Background and Objective: The HMG-box transcription factor Sox2 is essential for the maintenance of stem cells from early development to adult tissues. Sox2…”
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Abstract 427: Sox2 modulation of cancer stem cell behavior in GBM
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Background and Objective: Glioblastoma (GBM) is the most aggressive primary brain tumor. GBM cells are phenotypically plastic and can present cancer stem cell…”
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Sox2 Promotes Malignancy in Glioblastoma by Regulating Plasticity and Astrocytic Differentiation12
Published in Neoplasia (New York, N.Y.) (13-04-2014)“…The high-mobility group–box transcription factor sex-determining region Y–box 2 (Sox2) is essential for the maintenance of stem cells from early development to…”
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