Search Results - "Beretta, Lorenzo"
-
1
Defining the Role of Monocytes in Sjögren’s Syndrome
Published in International journal of molecular sciences (01-11-2022)“…Sjögren’s syndrome is one of the most prevalent autoimmune diseases after rheumatoid arthritis, with a preference for middle age, and is characterised by…”
Get full text
Journal Article -
2
Proteomic aptamer analysis reveals serum markers that characterize preclinical systemic sclerosis (SSc) patients at risk for progression toward definite SSc
Published in Arthritis research & therapy (27-01-2023)“…The study of molecular mechanisms characterizing disease progression may be relevant to get insights into systemic sclerosis (SSc) pathogenesis and to…”
Get full text
Journal Article -
3
The added value of right ventricular function normalized for afterload to improve risk stratification of patients with pulmonary arterial hypertension
Published in PloS one (19-05-2022)“…Risk stratification is central to the management of pulmonary arterial hypertension (PAH). For this purpose, multiparametric tools have been developed,…”
Get full text
Journal Article -
4
The interferon type I signature is present in systemic sclerosis before overt fibrosis and might contribute to its pathogenesis through high BAFF gene expression and high collagen synthesis
Published in Annals of the rheumatic diseases (01-08-2016)“…Interferon (IFN) signature has been reported in definite systemic sclerosis (SSc) but it has not been characterised in early SSc (EaSSc). We aim at…”
Get more information
Journal Article -
5
Preliminary safety and efficacy profile of prucalopride in the treatment of systemic sclerosis (SSc)-related intestinal involvement: results from the open label cross-over PROGASS study
Published in Arthritis research & therapy (20-06-2017)“…Prokinetics are used to treat enteric dismotility symptoms in systemic sclerosis (SSc) patients, but they often lack adequate efficacy. The most effective…”
Get full text
Journal Article -
6
The Long Non-coding RNA NRIR Drives IFN-Response in Monocytes: Implication for Systemic Sclerosis
Published in Frontiers in immunology (31-01-2019)“…TLR4 activation initiates a signaling cascade leading to the production of type I IFNs and of the downstream IFN-stimulated genes (ISGs). Recently, a number of…”
Get full text
Journal Article -
7
Prevalence of Pulmonary Hypertension in Systemic Sclerosis in European Caucasians and Metaanalysis of 5 Studies
Published in Journal of rheumatology (01-11-2010)“…To measure the prevalence of different types of pulmonary hypertension (PH) and to identify patients with systemic sclerosis (SSc) at highest risk in a…”
Get full text
Journal Article -
8
Earliest Phase of Systemic Sclerosis Typified by Increased Levels of Inflammatory Proteins in the Serum
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-12-2017)“…Objective Patients with definite systemic sclerosis (SSc) who lack fibrotic features can be stratified into an intermediate stage of disease severity between…”
Get full text
Journal Article -
9
Safety and effectiveness of abatacept in systemic sclerosis: The EUSTAR experience
Published in Seminars in arthritis and rheumatism (01-12-2020)“…To analyze the safety and effectiveness of abatacept (ABA) given in routine care to patients with systemic sclerosis (SSc). Retrospective multicenter…”
Get full text
Journal Article -
10
Urinary and plasma metabolite differences detected by HPLC-ESI-QTOF-MS in systemic sclerosis patients
Published in Journal of pharmaceutical and biomedical analysis (05-01-2019)“…•Metabolic differences in Systemic Sclerosis were found in plasma and urine samples.•The main deregulated metabolites were acylcarnitines, acylglycines and…”
Get full text
Journal Article -
11
Regional implantation of autologous adipose tissue-derived cells induces a prompt healing of long-lasting indolent digital ulcers in patients with systemic sclerosis
Published in Cell transplantation (01-01-2015)“…Digital ulcers (DUs) are a rather frequent and invalidating complication in systemic sclerosis (SSc), often showing a very slow or null tendency to heal, in…”
Get full text
Journal Article -
12
Reactome pathway analysis from whole-blood transcriptome reveals unique characteristics of systemic sclerosis patients at the preclinical stage
Published in Frontiers in immunology (2023)“…This study aims to characterize differential expressed pathways (DEP) in subjects with preclinical systemic sclerosis (PreSSc) characterized uniquely by…”
Get full text
Journal Article -
13
-
14
Cardiac autonomic modulation at rest and during orthostatic stress among different systemic sclerosis subsets
Published in European journal of internal medicine (01-08-2019)“…To compare autonomic heart rate variability (HRV) parameters at rest and during active stand in a population of SSc patients, taking into account SSc subsets…”
Get full text
Journal Article -
15
Angiopoietin-2 Promotes Inflammatory Activation in Monocytes of Systemic Sclerosis Patients
Published in International journal of molecular sciences (15-12-2020)“…Angiopoietin-2 (Ang-2), a ligand of the tyrosine kinase receptor Tie2, is essential for vascular development and blood vessel stability and is also involved in…”
Get full text
Journal Article -
16
Transcutaneous auricular branch vagal nerve stimulation as a non-invasive add-on therapeutic approach for pain in systemic sclerosis
Published in Rheumatic & musculoskeletal diseases open (01-08-2023)“…ObjectiveSystemic sclerosis (SSc) is an autoimmune disease with health-related quality of life (HRQoL) high impairment. Pain is of paramount importance to be…”
Get full text
Journal Article -
17
Automatic design of chiral mechanical metamaterials
Published in APL materials (01-10-2021)“…Automatic design of mechanical metamaterials is key to achieving efficiencies in terms of a desired functionality that can far exceed the rationally designed…”
Get full text
Journal Article -
18
Sympatho-Vagal Dysfunction in Systemic Sclerosis: A Follow-Up Study
Published in Life (Basel, Switzerland) (23-12-2022)“…Systemic sclerosis (SSc) patients often present cardiovascular autonomic dysfunction, which is associated with the risk of arrhythmic complications and…”
Get full text
Journal Article -
19
Serum profiling identifies CCL8, CXCL13, and IL-1RA as markers of active disease in patients with systemic lupus erythematosus
Published in Frontiers in immunology (2023)“…Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease that presents a challenge for clinicians. To identify potential biomarkers for…”
Get full text
Journal Article -
20
Real-life efficacy and safety of nintedanib in systemic sclerosis-interstitial lung disease: data from an Italian multicentre study
Published in Rheumatic & musculoskeletal diseases open (01-02-2023)“…IntroductionNintedanib (NTD) has been shown to be effective in systemic sclerosis (SSc)-interstitial lung disease (ILD). Here we describe the efficacy and…”
Get full text
Journal Article