Search Results - "Berest, Ivan"

Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis by Ranzoni, Anna Maria, Tangherloni, Andrea, Berest, Ivan, Riva, Simone Giovanni, Myers, Brynelle, Strzelecka, Paulina M., Xu, Jiarui, Panada, Elisa, Mohorianu, Irina, Zaugg, Judith B., Cvejic, Ana

“…Regulation of hematopoiesis during human development remains poorly defined. Here we applied single-cell RNA sequencing (scRNA-seq) and single-cell assay for…”
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Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension by Reyes-Palomares, Armando, Gu, Mingxia, Grubert, Fabian, Berest, Ivan, Sa, Silin, Kasowski, Maya, Arnold, Christian, Shuai, Mao, Srivas, Rohith, Miao, Simon, Li, Dan, Snyder, Michael P., Rabinovitch, Marlene, Zaugg, Judith B.

“…Environmental and epigenetic factors often play an important role in polygenic disorders. However, how such factors affect disease-specific tissues at the…”
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TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells by Rasmussen, Kasper D, Berest, Ivan, Keβler, Sandra, Nishimura, Koutarou, Simón-Carrasco, Lucía, Vassiliou, George S, Pedersen, Marianne T, Christensen, Jesper, Zaugg, Judith B, Helin, Kristian

“…The epigenetic regulator is frequently mutated in hematological diseases. Mutations have been shown to arise in hematopoietic stem cells early in disease…”
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Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: diffTF by Berest, Ivan, Arnold, Christian, Reyes-Palomares, Armando, Palla, Giovanni, Rasmussen, Kasper Dindler, Giles, Holly, Bruch, Peter-Martin, Huber, Wolfgang, Dietrich, Sascha, Helin, Kristian, Zaugg, Judith B.

“…Transcription factors (TFs) regulate many cellular processes and can therefore serve as readouts of the signaling and regulatory state. Yet for many TFs, the…”
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Drug‐microenvironment perturbations reveal resistance mechanisms and prognostic subgroups in CLL by Bruch, Peter‐Martin, Giles, Holly AR, Kolb, Carolin, Herbst, Sophie A, Becirovic, Tina, Roider, Tobias, Lu, Junyan, Scheinost, Sebastian, Wagner, Lena, Huellein, Jennifer, Berest, Ivan, Kriegsmann, Mark, Kriegsmann, Katharina, Zgorzelski, Christiane, Dreger, Peter, Zaugg, Judith B, Müller‐Tidow, Carsten, Zenz, Thorsten, Huber, Wolfgang, Dietrich, Sascha

“…The tumour microenvironment and genetic alterations collectively influence drug efficacy in cancer, but current evidence is limited and systematic analyses are…”
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Integration of scATAC-Seq with scRNA-Seq Data by Berest, Ivan, Tangherloni, Andrea

“…Single-cell studies are enabling our understanding of the molecular processes of normal cell development and the onset of several pathologies. For instance,…”
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Inflammatory Mediators Suppress FGFR2 Expression in Human Keratinocytes to Promote Inflammation by Ferrarese, Luca, Koch, Michael, Baumann, Artemis, Bento-Lopes, Liliana, Wüst, Daria, Berest, Ivan, Kopf, Manfred, Werner, Sabine

“…Fibroblast growth factors (FGFs) are key orchestrators of development, tissue homeostasis and repair. FGF receptor (FGFR) deficiency in mouse keratinocytes…”
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