Search Results - "Beresford, J N"

High concentrations of dexamethasone suppress the proliferation but not the differentiation or further maturation of human osteoblast precursors in vitro: relevance to glucocorticoid‐induced osteoporosis by Walsh, S., Jordan, G. R., Jefferiss, C., Stewart, K., Beresford, J. N.

“…Objective. The use of glucocorticoids (GCs) in the treatment of RA is a frequent cause of bone loss. In vitro, however, this same class of steroids has been…”
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Expression of the developmental markers STRO-1 and alkaline phosphatase in cultures of human marrow stromal cells: regulation by fibroblast growth factor (FGF)-2 and relationship to the expression of FGF receptors 1–4 by Walsh, S, Jefferiss, C, Stewart, K, Jordan, G.R, Screen, J, Beresford, J.N

“…Autologous marrow stromal cells have been proposed as an adjuvant in the treatment of bone defects and diseases. This will require the development of culture…”
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Methotrexate in the treatment of rheumatoid arthritis. II. In vivo effects on bone mineral density by Minaur, N. J., Kounali, D., Vedi, S., Compston, J. E., Beresford, J. N., Bhalla, A. K.

“…Objective. To determine the effect of methotrexate (MTX) on bone mineral density (BMD) in rheumatoid arthritis (RA). Methods. One hundred and sixteen…”
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Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures by Beresford, J N, Bennett, J H, Devlin, C, Leboy, P S, Owen, M E

“…The differentiation of adipocytic and osteogenic cells has been investigated in cultures of adult rat marrow stromal cells. Adipocytic differentiation was…”
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Vascular Pericytes Express Osteogenic Potential In Vitro and In Vivo by Doherty, Mary Jo, Ashton, Brian A., Walsh, Susan, Beresford, Jon N., Grant, Michael E., Canfield, Ann E.

“…At postconfluence, cultured bovine pericytes isolated from retinal capillaries form three‐dimensional nodule‐like structures that mineralize. Using a…”
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IGF-I does not affect the proliferation or early osteogenic differentiation of human marrow stromal cells by Walsh, S, Jefferiss, C.M, Stewart, K, Beresford, J.N

“…The ability of insulin-like growth factor-I (IGF-I) to regulate the proliferation and differentiation of primitive osteogenic precursors (CFU-F) has been…”
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Osteogenic stem cells and the stromal system of bone and marrow by Beresford, J N

“…According to current hypothesis, cells of the osteogenic lineage, which includes both osteoblasts and chondroblasts, are derived from a stromal stem cell in…”
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Further Characterization of Cells Expressing STRO‐1 in Cultures of Adult Human Bone Marrow Stromal Cells by Stewart, Karina, Walsh, Susan, Screen, Joanne, Jefferiss, Carolyn M., Chainey, Jonathan, Jordan, Grant R., Beresford, Jon N.

“…Primitive cells of the osteoblast lineage are not well characterized but are known to be present within the STRO‐1+ fraction of adult human bone and marrow. A…”
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Methotrexate in the treatment of rheumatoid arthritis. I. In vitro effects on cells of the osteoblast lineage by Minaur, N. J., Jefferiss, C., Bhalla, A. K., Beresford, J. N.

“…Objective. Low‐dose methotrexate (MTX) is often used in the treatment of rheumatoid arthritis (RA). To be effective, treatment must be long‐term, and there are…”
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P‐selectin antagonism reduces thrombus formation in humans by CHELLIAH, R., LUCKING, A. J., TATTERSALL, L., DAGA, S., BERESFORD‐CLEARY, N. J., CORTAS, K., FOX, K. A. A., FEUERSTEIN, G. Z., CONNOLLY, T. M., NEWBY, D. E.

“…Background: Interaction of P‐selectin with its glycoprotein ligand (P‐selectin glycoprotein ligand type 1) mediates inflammatory processes that may also…”
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In vitro effects of growth factors and dexamethasone on rat marrow stromal cells by Locklin, R M, Williamson, M C, Beresford, J N, Triffitt, J T, Owen, M E

“…Bone marrow contains multipotential stromal stem cells that can differentiate into fibroblastic, osteogenic, adipocytic, and other cell lines. There is…”
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Patterns of integrin expression in a human mandibular explant model of osteoblast differentiation by Bennett, J.H, Carter, D.H, Alavi, A.L, Beresford, J.N, Walsh, S

“…Cell–matrix interaction is crucial in regulating osteoblast differentiation and function. These interactions are themselves regulated, at least in part, by…”
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1,25-Dihydroxyvitamin D3 and human bone-derived cells in vitro: effects on alkaline phosphatase, type I collagen and proliferation by Beresford, J N, Gallagher, J A, Russell, R G

“…1,25-Dihydroxyvitamin D3 [1,25-(OH)2D3], but not 24,25-(OH)2D3 stimulates the alkaline phosphatase activity of cultured human bone cell populations. The…”
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Detection of Xanthomonas fragariae and presumptive detection of Xanthomonas arboricola pv. fragariae, from strawberry leaves, by real-time PCR by Weller, S.A., Beresford-Jones, N.J., Hall, J., Thwaites, R., Parkinson, N., Elphinstone, J.G.

“…Real-time (TaqMan) PCR assays were developed to detect the strawberry angular leaf spot pathogen Xanthomonas fragariae ( Xf) and the strawberry bacterial…”
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Expression and secretion of parathyroid hormone‐related protein by human bone‐derived cells in vitro: Effects of glucocorticoids by Walsh, C.A., Birch, M.A., Fraser, W.D., Lawton, R., Dorgan, J., Walsh, S., Sansom, D., Beresford, J.N., Gallagher, J.A.

“…We investigated the production of parathyroid hormone‐related protein (PTHrP) by cells derived from explants of human bone. Using an immunoradiometric assay…”
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Application of reflected light microscopy to identify and quantitate resorption by isolated osteoclasts by Walsh, C.A., Beresford, J.N., Birch, M.A., Boothroyd, B., Gallagher, J.A.

“…A simple technique has been developed to identify the resorption lacunae excavated by avian osteoclasts in vitro. Briefly, devitalized bovine bone wafers, with…”
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A number of osteocalcin antisera recognize epitopes on proteins other than osteocalcin in cultured skin fibroblasts: Implications for the identification of cells of the osteoblastic lineage in vitro by Bradbeer, J.N., Virdi, A.S., Serre, C.M., Beresford, J.N., Delmas, P.D., Reeve, J., Triffitt, J.T.

“…Rabbit antisera to bovine osteocalcin were produced independently in two laboratories and their specificities established by western blot analysis. By…”
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Analysis of the proteoglycans synthesized by human bone cells in vitro by Beresford, J N, Fedarko, N S, Fisher, L W, Midura, R J, Yanagishita, M, Termine, J D, Robey, P G

“…Proteoglycans were isolated by ion-exchange chromatography from the extracted cell layer and culture medium of human bone cell cultures following incubation in…”
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Vitamin D metabolites regulate osteocalcin synthesis and proliferation of human bone cells in vitro by Skjødt, H, Gallagher, J A, Beresford, J N, Couch, M, Poser, J W, Russell, R G

“…The effects of six natural vitamin D metabolites of potential biological and therapeutic interest, 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3), 25-hydroxyvitamin…”
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Dexamethasone induction of osteoblast mRNAs in rat marrow stromal cell cultures by Leboy, P S, Beresford, J N, Devlin, C, Owen, M E

“…We have examined the ability of dexamethasone, retinoic acid, and vitamin D3 to induce osteogenic differentiation in rat marrow stromal cell cultures by…”
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