Search Results - "Beresewicz, Andrzej"

Induction of inducible nitric oxide synthase expression in ammonia‐exposed cultured astrocytes is coupled to increased arginine transport by upregulated y+LAT2 transporter by Zielińska, Magdalena, Milewski, Krzysztof, Skowrońska, Marta, Gajos, Anna, Ziemińska, Elżbieta, Beręsewicz, Andrzej, Albrecht, Jan

“…One of the aspects of ammonia toxicity to brain cells is increased production of nitric oxide (NO) by NO synthases (NOSs). Previously we showed that ammonia…”
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Enjoy your heart-beets. The role of dietary inorganic nitrate in cardiovascular health by Beręsewicz, Andrzej, Gajos-Draus, Anna

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Cardiac and renal upregulation of Nox2 and NF‐κB and repression of Nox4 and Nrf2 in season‐ and diabetes‐mediated models of vascular oxidative stress in guinea‐pig and rat by Gajos‐Draus, Anna, Duda, Monika, Beręsewicz, Andrzej

“…The superoxide‐forming NADPH oxidase homologues, Nox1, Nox2, and Nox5, seem to mediate the pro‐atherosclerotic vascular phenotype. The hydrogen…”
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Seasonal superoxide overproduction and endothelial activation in guinea-pig heart; seasonal oxidative stress in rats and humans by Konior, Anna, Klemenska, Emilia, Brudek, Magdalena, Podolecka, Ewa, Czarnowska, Elżbieta, Beręsewicz, Andrzej

“…Abstract Seasonality in endothelial dysfunction and oxidative stress was noted in humans and rats, suggesting it is a common phenomenon of a potential clinical…”
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Changes in ion channel gene expression underlying heart failure-induced sinoatrial node dysfunction by Yanni, Joseph, Tellez, James O, Maczewski, Michal, Mackiewicz, Urszula, Beresewicz, Andrzej, Billeter, Rudi, Dobrzynski, Halina, Boyett, M R

“…Heart failure (HF) causes a decline in the function of the pacemaker of the heart-the sinoatrial node (SAN). The aim of the study was to investigate HF-induced…”
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Glutamine inhibits ammonia-induced accumulation of cGMP in rat striatum limiting arginine supply for NO synthesis by Hilgier, Wojciech, Fręśko, Inez, Klemenska, Emilia, Beręsewicz, Andrzej, Oja, Simo S, Saransaari, Pirjo, Albrecht, Jan, Zielińska, Magdalena

“…Abstract Brain l -glutamine (Gln) accumulation and increased activity of the NO/cGMP pathway are immediate consequences of acute exposure to ammonia. This…”
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P2 purinergic receptor mRNA in rat and human sinoatrial node and other heart regions by Musa, Hanny, Tellez, James O., Chandler, Natalie J., Greener, Ian D., Mączewski, Michał, Mackiewicz, Urszula, Beresewicz, Andrzej, Molenaar, Peter, Boyett, Mark R., Dobrzynski, Halina

“…It is known that adenosine 5′-triphosphate (ATP) is a cotransmitter in the heart. Additionally, ATP is released from ischemic and hypoxic myocytes. Therefore,…”
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The Role of Adenosine and ATP-sensitive Potassium Channels in the Protection Afforded by Ischemic Preconditioning Against the Post-ischemic Endothelial Dysfunction in Guinea-pig Hearts by Maczewski, Michal, Beresewicz, Andrzej

“…The role of adenosine and ATP-sensitive potassium channels (KATP) in the mechanism of ischemic preconditioning (IPC)-induced protection against the…”
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The Role of Endothelin, Protein Kinase C and Free Radicals in the Mechanism of the Post-ischemic Endothelial Dysfunction in Guinea-pig Hearts by Maczewski, Michal, Beresewicz, Andrzej

“…Transient ischemia has been shown to impair endothelium-dependent, but not endothelium-independent, coronary vasodilation, indicating selective endothelial…”
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Role of nitric oxide and free radicals in cardioprotection by blocking Na+/H+ and Na+/Ca2+ exchange in rat heart by MACZEWSKI, Michal, BERESEWICZ, Andrzej

“…Inhibition of Na(+)/H(+) (NHE) and Na(+)/Ca(2+) (NCE) exchangers prevents myocardial ischemia/reperfusion injury by preventing cardiomyocyte Ca(2+) overload…”
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Low-density lipoprotein reduction by simvastatin is accompanied by angiotensin II type 1 receptor downregulation, reduced oxidative stress, and improved endothelial function in patients with stable coronary artery disease by Kiliszek, Marek, Maczewski, Michał, Styczyński, Grzegorz, Duda, Monika, Opolski, Grzegorz, Beresewicz, Andrzej

“…OBJECTIVESWe tested the hypothesis that low-density lipoprotein-cholesterol induces angiotensin II type 1 receptor upregulation that, in turn, accounts for…”
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Effect of Glutamine Synthesis Inhibition with Methionine Sulfoximine on the Nitric Oxide–Cyclic GMP Pathway in the Rat Striatum Treated Acutely with Ammonia: A Microdialysis Study by Hilgier, Wojciech, Węgrzynowicz, Michal, Mączewski, Michal, Beręsewicz, Andrzej, Oja, Simo S., Saransaari, Pirjo, Albrecht, Jan

“…Ammonia neurotoxicity is associated with overactivation of N -methyl- d -aspartate (NMDA) receptors leading to enhanced nitric oxide and cyclic GMP synthesis…”
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Preconditioning protects endothelium by preventing ET-1-induced activation of NADPH oxidase and xanthine oxidase in post-ischemic heart by Duda, Monika, Konior, Anna, Klemenska, Emilia, Beręsewicz, Andrzej

“…Abstract The hypothesis was tested that endothelin-1 (ET-1)-induced superoxide (O2− ) generation mediates post-ischemic coronary endothelial injury, that…”
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Obligatory role of intraluminal O2- in acute endothelin-1 and angiotensin II signaling to mediate endothelial dysfunction and MAPK activation in guinea-pig hearts by Wojtera, Emilia, Konior, Anna, Fedoryszak-Kuśka, Natalia, Beręsewicz, Andrzej

“…We hypothesized that, due to a cross-talk between cytoplasmic O2--sources and intraluminally expressed xanthine oxidase (XO), intraluminal O2- is instrumental…”
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Effect of classic preconditioning and diazoxide on endothelial function and O2 − and NO generation in the post-ischemic guinea-pig heart by Beręsewicz, Andrzej, Mączewski, Michał, Duda, Monika

“…Abstract Objectives: A hypothesis was tested that a reaction product between superoxide (O2 −) and nitric oxide (NO) mediates post-ischemic coronary…”
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Bioactivation of organic nitrates and the mechanism of nitrate tolerance by Klemenska, Emila, Beresewicz, Andrzej

“…Organic nitrates, such as nitroglycerin, are commonly used in the therapy of cardiovascular disease. Long-term therapy with these drugs, however, results in…”
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Ageing‐dependent remodelling of ion channel and Ca2+ clock genes underlying sino‐atrial node pacemaking by Tellez, James O., Mączewski, Michal, Yanni, Joseph, Sutyagin, Pavel, Mackiewicz, Urszula, Atkinson, Andrew, Inada, Shin, Beresewicz, Andrzej, Billeter, Rudi, Dobrzynski, Halina, Boyett, M. R.

“…The function of the sino‐atrial node (SAN), the pacemaker of the heart, is known to decline with age, resulting in pacemaker disease in the elderly. The aim of…”
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Endothelin in the mechanism of endothelial injury and neutrophil adhesion in the post-ischemic guinea-pig heart by Kurzelewski, Michał, Czarnowska, Elżbieta, Beręsewicz, Andrzej

“…This study addressed the hypothesis that endothelin promotes neutrophil accumulation in ischemic/reperfused myocardium, not only via its direct effect on…”
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Antioxidative activity of sulodexide, a glycosaminoglycan, in patients with stable coronary artery disease: a pilot study by Bilinska, Maria, Wolszakiewicz, Jadwiga, Duda, Monika, Janas, Jadwiga, Beresewicz, Andrzej, Piotrowicz, Ryszard

“…Oxidative stress may promote chronic inflammation and contribute to accelerated atherogenesis in patients with coronary artery disease (CAD). Sulodexide, a…”
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ET-1-induced O2− generation and endothelial dysfunction in guinea-pig heart; role of PKC, mitochondria, NADPH and xanthine oxidase by Klemenska, Emilia, Konior, Anna, Beresewicz, Andrzej

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