Search Results - "Berdiel Acer, Mireia"
-
1
IFNβ1 secreted by breast cancer cells undergoing chemotherapy reprograms stromal fibroblasts to support tumour growth after treatment
Published in Molecular oncology (01-05-2021)“…Chemotherapy (CTX) remains the standard of care for most aggressive tumours, including breast cancer (BC). In BC chemotherapeutic regimens, the maximum…”
Get full text
Journal Article -
2
Hepatic Carcinoma—Associated Fibroblasts Promote an Adaptative Response in Colorectal Cancer Cells That Inhibit Proliferation and Apoptosis: Nonresistant Cells Die by Nonapoptotic Cell Death
Published in Neoplasia (New York, N.Y.) (01-10-2011)“…Abstract Carcinoma-associated fibroblasts (CAFs) are important contributors of microenvironment in determining the tumor’s fate. This study aimed to compare…”
Get full text
Journal Article -
3
Stromal NRG1 in luminal breast cancer defines pro-fibrotic and migratory cancer-associated fibroblasts
Published in Oncogene (15-04-2021)“…HER3 is highly expressed in luminal breast cancer subtypes. Its activation by NRG1 promotes activation of AKT and ERK1/2, contributing to tumour progression…”
Get full text
Journal Article -
4
Carcinoma-associated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells
Published in Oncotarget (13-09-2016)“…The importance of tumor microenvironment (TME) as a relevant contributor to cancer progression and its role in the development of de novo resistance to…”
Get full text
Journal Article -
5
Lurbinectedin (PM01183), a New DNA Minor Groove Binder, Inhibits Growth of Orthotopic Primary Graft of Cisplatin-Resistant Epithelial Ovarian Cancer
Published in Clinical cancer research (01-10-2012)“…Epithelial ovarian cancer (EOC) is the fifth leading cause of death in women diagnosed with gynecologic malignancies. The low survival rate is because of its…”
Get full text
Journal Article -
6
A 5-gene classifier from the carcinoma-associated fibroblast transcriptomic profile and clinical outcome in colorectal cancer
Published in Oncotarget (15-08-2014)“…Based on 108 differentially expressed genes between carcinoma-associated fibroblasts (CAFs) and paired normal colonic fibroblasts we recently reported, a…”
Get full text
Journal Article -
7
A monotonic and prognostic genomic signature from fibroblasts for colorectal cancer initiation, progression, and metastasis
Published in Molecular cancer research (01-09-2014)“…The differential gene expression patterns between normal colonic fibroblasts (NCF), carcinoma-associated fibroblasts from primary tumors (CAF-PT), and CAFs…”
Get full text
Journal Article -
8
Abstract PS16-36: Paracrine signalling with stromal fibroblasts drives recovery of cancer cells after chemotherapy treatment
Published in Cancer research (Chicago, Ill.) (15-02-2021)“…Abstract Introduction: The main cause of death for cancer patients is the development of metastasis. These arise mainly due to irresponsiveness of cancer cells…”
Get full text
Journal Article -
9
Abstract P1-08-15: Communication between tumor cells and fibroblasts as a prognostic factor of NACT in TNBC
Published in Cancer research (Chicago, Ill.) (15-02-2022)“…Abstract Introduction. Neoadjuvant chemotherapy (NACT) is the standard of care in aggressive breast cancer, including triple negative breast cancer (TNBC)…”
Get full text
Journal Article -
10
Noncanonical TGFβ Pathway Relieves the Blockade of IL1β/TGFβ-Mediated Crosstalk between Tumor and Stroma: TGFBR1 and TAK1 Inhibition in Colorectal Cancer
Published in Clinical cancer research (15-07-2019)“…The aim of the study is blocking the recruitment of a protective stroma by altering the crosstalk between normal stromal cells and tumor cells for stripping…”
Get full text
Journal Article -
11
Abstract 3329: Combinatorial blockade of ERBB receptors in HER2 low breast cancer
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Large number of breast cancer patients clinically classified as HER2 negative, show low/moderate levels of HER2 along with other ERBB receptors…”
Get full text
Journal Article -
12
Disentangling ERBB Signaling in Breast Cancer Subtypes-A Model-Based Analysis
Published in Cancers (12-05-2022)“…Targeted therapies have shown striking success in the treatment of cancer over the last years. However, their specific effects on an individual tumor appear to…”
Get full text
Journal Article -
13
Differences between CAFs and their paired NCF from adjacent colonic mucosa reveal functional heterogeneity of CAFs, providing prognostic information
Published in Molecular oncology (01-10-2014)“…Little is known about the difference in gene expression between carcinoma-associated fibroblasts (CAFs) and paired normal colonic fibroblasts (NCFs) in…”
Get full text
Journal Article -
14
Hepatic Carcinoma-Associated Fibroblasts Promote an Adaptative Response in Colorectal Cancer Cells That Inhibit Proliferation and Apoptosis: Nonresistant Cells Die by Nonapoptotic Cell Death1
Published in Neoplasia (New York, N.Y.) (01-10-2011)“…Carcinoma-associated fibroblasts (CAFs) are important contributors of microenvironment in determining the tumor's fate. This study aimed to compare the…”
Get full text
Journal Article -
15
Hepatic carcinoma-associated fibroblasts promote an adaptative response in colorectal cancer cells that inhibit proliferation and apoptosis: nonresistant cells die by nonapoptotic cell death
Published in Neoplasia (New York, N.Y.) (01-10-2011)“…Carcinoma-associated fibroblasts (CAFs) are important contributors of microenvironment in determining the tumor's fate. This study aimed to compare the…”
Get full text
Journal Article