Search Results - "Berde, B"

Electroencephalographic features of discontinuous activity in anesthetized infants and children by Agrawal, Uday, Berde, Charles B, Cornelissen, Laura

“…Discontinuous electroencephalographic activity in children is thought to reflect brain inactivation. Discontinuity has been observed in states of pathology,…”
Get full text

A framework for individualized splice-switching oligonucleotide therapy by Kim, Jinkuk, Woo, Sijae, de Gusmao, Claudio M., Zhao, Boxun, Chin, Diana H., DiDonato, Renata L., Nguyen, Minh A., Nakayama, Tojo, Hu, Chunguang April, Soucy, Aubrie, Kuniholm, Ashley, Thornton, Jennifer Karlin, Riccardi, Olivia, Friedman, Danielle A., El Achkar, Christelle Moufawad, Dash, Zane, Cornelissen, Laura, Donado, Carolina, Faour, Kamli N. W., Bush, Lynn W., Suslovitch, Victoria, Lentucci, Claudia, Park, Peter J., Lee, Eunjung Alice, Patterson, Al, Philippakis, Anthony A., Margus, Brad, Berde, Charles B., Yu, Timothy W.

“…Splice-switching antisense oligonucleotides (ASOs) could be used to treat a subset of individuals with genetic diseases 1 , but the systematic identification…”
Get full text

Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants by Cornelissen, Laura, Kim, Seong-Eun, Purdon, Patrick L, Brown, Emery N, Berde, Charles B

“…Electroencephalogram (EEG) approaches may provide important information about developmental changes in brain-state dynamics during general anesthesia. We used…”
Get full text

Tactile sensitivity and motor coordination in infancy: Effect of age, prior surgery, anaesthesia & critical illness by Cornelissen, Laura, Underwood, Ellen, Gabard-Durnam, Laurel J, Soto, Melissa, Tao, Alice, Lobo, Kimberly, Hensch, Takao K, Berde, Charles B

“…Tactile sensitivity in the infant period is poorly characterized, particularly among children with prior surgery, anaesthesia or critical illness. The study…”
Get full text

Modified Sensory Testing in Non-verbal Patients Receiving Novel Intrathecal Therapies for Neurological Disorders by Cornelissen, Laura, Donado, Carolina, Yu, Timothy W, Berde, Charles B

“…Several neurological disorders may be amenable to treatment with gene-targeting therapies such as antisense oligonucleotides (ASOs) or viral vector-based gene…”
Get full text

Racial and Ethnic Disparities in Pain Management of Children With Limb Fractures or Suspected Appendicitis: A Retrospective Cross-Sectional Study by Guedj, Romain, Marini, Maddalena, Kossowsky, Joe, Berde, Charles B., Kimia, Amir A., Fleegler, Eric W.

“…Objective: To evaluate whether racial/ethnical differences in analgesia administration existed in two different cohorts of children with painful conditions:…”
Get full text

Neurodevelopment of children exposed to prolonged anesthesia in infancy: GABA study interim analysis of resting-state brain networks at 2, 4, and 10-months old by Desowska, Adela, Coffman, Siobhan, Kim, Isabelle, Underwood, Ellen, Tao, Alice, Lopez, Kelsie L., Nelson, Charles A., Hensch, Takao K., Gabard-Durnam, Laurel, Cornelissen, Laura, Berde, Charles B.

“…•Brain networks develop through the first year of life under the influence of genetics and environment.•Previous research has given variable conclusions…”
Get full text

Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model by WEN, Yeong-Ray, SUTER, Marc R, KAWASAKI, Yasuhiko, JIN HUANG, PERTIN, Marie, KOHNO, Tatsuro, BERDE, Charles B, DECOSTERD, Isabelle, JI, Ru-Rong

“…Current evidence indicates that p38 mitogen-activated protein kinase activation in spinal microglia contributes to the development of neuropathic pain…”
Get full text

Neural Correlates of Anesthesia in Newborn Mice and Humans by Chini, Mattia, Gretenkord, Sabine, Kostka, Johanna K, Pöpplau, Jastyn A, Cornelissen, Laura, Berde, Charles B, Hanganu-Opatz, Ileana L, Bitzenhofer, Sebastian H

“…Monitoring the hypnotic component of anesthesia during surgeries is critical to prevent intraoperative awareness and reduce adverse side effects. For this…”
Get full text

Immediate rescue designs in pediatric analgesic trials: a systematic review and meta-analysis by Kossowsky, Joe, Donado, Carolina, Berde, Charles B

“…Designing analgesic clinical trials in pediatrics requires a balance between scientific, ethical, and practical concerns. A previous consensus group…”
Get full text

Periaqueductal gray neuroplasticity following chronic morphine varies with age: Role of oxidative stress by Bajic, D, Berde, C.B, Commons, K.G

“…Highlights ► Acute morphine activates Fos in the ventral PAG in both adult and newborn rat at PD7. ► This effect was attenuated after chronic morphine…”
Get full text

The Effectiveness of Cancer Pain Management in a Tertiary Hospital Outpatient Pain Clinic in Thailand: A Prospective Observational Study by Wangnamthip, Suratsawadee, Panchoowong, Skaorat, Donado, Carolina, Lobo, Kimberly, Phankhongsap, Pimporn, Sriveerachai, Pinyo, Euasobhon, Pramote, Rushatamukayanunt, Pranee, Mandee, Sahatsa, Zinboonyahgoon, Nantthasorn, Berde, Charles B.

“…Context. In a previous retrospective study, cancer pain management was effective in 47.5% of a cohort assessed after 3 months in a pain clinic at Siriraj…”
Get full text

Regional Anesthesia Approaches to Pain Management in Pediatric Palliative Care: A Review of Current Knowledge by Rork, Jillian F., BA, Berde, Charles B., MD, PhD, Goldstein, Richard D., MD

“…Abstract Context Although systemic analgesic therapies are the mainstay of pain treatment in pediatric palliative care, there are cases where they fail to…”
Get full text

Activation of Peripheral NMDA Receptors Contributes to Human Pain and Rat Afferent Discharges Evoked by Injection of Glutamate into the Masseter Muscle by Cairns, Brian E, Svensson, Peter, Wang, Kelun, Hupfeld, Steen, Graven-Nielsen, Thomas, Sessle, Barry J, Berde, Charles B, Arendt-Nielsen, Lars

“…1 Department of Anesthesia, Harvard Medical School/Children's Hospital, Boston Massachusetts, 02115 2 Department of Clinical Oral Physiology, Dental School,…”
Get full text

Association of Genetic Variants With Migraine Subclassified by Clinical Symptoms in Adult Females by Kossowsky, Joe, Schuler, Megan S, Giulianini, Franco, Berde, Charles B, Reis, Ben, Ridker, Paul M, Buring, Julie E, Kurth, Tobias, Chasman, Daniel I

“…Migraine is heritable and formally diagnosed by structured criteria that require presence of some but not all possible migraine symptoms which include aura,…”
Get full text

Endogenous cholinergic neurotransmission contributes to behavioral sensitization to morphine by Bajic, Dusica, Soiza-Reilly, Mariano, Spalding, Allegra L, Berde, Charles B, Commons, Kathryn G

“…Neuroplasticity in the mesolimbic dopaminergic system is critical for behavioral adaptations associated with opioid reward and addiction. These processes may…”
Get full text

Tetrodotoxin-bupivacaine-epinephrine combinations for prolonged local anesthesia by Berde, Charles B, Athiraman, Umeshkumar, Yahalom, Barak, Zurakowski, David, Corfas, Gabriel, Bognet, Christina

“…Currently available local anesthetics have analgesic durations in humans generally less than 12 hours. Prolonged-duration local anesthetics will be useful for…”
Get full text

Summary proceedings from the neonatal pain-control group by ANAND, Kanwaljeet J. S, ARANDA, Jacob V, LYNN, Anne M, MAXWELL, Lynne G, OBERLANDER, Tim F, RAJU, Tonse N. K, SORIANO, Sulpicio G, TADDIO, Anna, WALCO, Gary A, BERDE, Charles B, BUCKMAN, Shaavhrée, CAPPARELLI, Edmund V, CARLO, Waldemar, HUMMEL, Patricia, CELESTE JOHNSTON, C, LANTOS, John, TUTAG-LEHR, Victoria

“…Recent advances in neurobiology and clinical medicine have established that the fetus and newborn may experience acute, established, and chronic pain. They…”
Get full text

Initial Adjustment to the COVID-19 Pandemic and the Associated Shutdown in Children and Adolescents With Chronic Pain and Their Families by Kaczynski, Karen J, Chang, Cindy Yu Hsing, Chimoff, Justin, Koike, Camila, Berde, Charles B, Logan, Deirdre E, Nelson, Sarah, Kossowsky, Joe

“…Youth with chronic pain often struggle to function in multiple domains due to pain and associated psychosocial distress. In 2020, schools and businesses shut…”
Get full text

Children and adolescents with complex regional pain syndrome: more psychologically distressed than other children in pain? by Logan, Deirdre E, Williams, Sara E, Carullo, Veronica P, Claar, Robyn Lewis, Bruehl, Stephen, Berde, Charles B

“…Historically, in both adult and pediatric populations, a lack of knowledge regarding complex regional pain syndrome (CRPS) and absence of clear diagnostic…”
Get full text