Search Results - "Berchtold, Martin W."

The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer by Berchtold, Martin W., Villalobo, Antonio

“…Calmodulin (CaM) is a ubiquitous Ca2+ receptor protein mediating a large number of signaling processes in all eukaryotic cells. CaM plays a central role in…”
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The Role of Calmodulin in Tumor Cell Migration, Invasiveness, and Metastasis by Villalobo, Antonio, Berchtold, Martin W

“…Calmodulin (CaM) is the principal Ca sensor protein in all eukaryotic cells, that upon binding to target proteins transduces signals encoded by global or…”
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ALG-2 participates in recovery of cells after plasma membrane damage by electroporation and digitonin treatment by la Cour, Jonas M, Winding Gojkovic, Pernille, Ambjørner, Sophie E B, Bagge, Jonas, Jensen, Simone M, Panina, Svetlana, Berchtold, Martin W

“…The calcium binding protein ALG-2 is upregulated in several types of cancerous tissues and cancer cell death may be a consequence of ALG-2 downregulation…”
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Calcium Ion in Skeletal Muscle: Its Crucial Role for Muscle Function, Plasticity, and Disease by Berchtold, Martin W, Brinkmeier, Heinrich, Muntener, Markus

“…Department of Molecular Cell Biology, Institute of Molecular Biology, University of Copenhagen, Copenhagen, Denmark; Department of General Physiology,…”
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ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex by la Cour, Jonas M, Schindler, Adam J, Berchtold, Martin W, Schekman, Randy

“…Coated vesicles mediate the traffic of secretory and membrane cargo proteins from the endoplasmic reticulum (ER) to the Golgi apparatus. The coat protein…”
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OSCAR‐collagen signaling in monocytes plays a proinflammatory role and may contribute to the pathogenesis of rheumatoid arthritis by Schultz, Heidi S., Guo, Li, Keller, Pernille, Fleetwood, Andrew J., Sun, Mingyi, Guo, Wei, Ma, Chunyan, Hamilton, John A., Bjørkdahl, Olle, Berchtold, Martin W., Panina, Svetlana

“…Osteoclast‐associated receptor (OSCAR) is an activating receptor expressed by human myeloid cells. Collagen type I (ColI) and collagen type II (ColII) serve as…”
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Collagen induces maturation of human monocyte-derived dendritic cells by signaling through osteoclast-associated receptor by Schultz, Heidi S, Nitze, Louise M, Zeuthen, Louise H, Keller, Pernille, Gruhler, Albrecht, Pass, Jesper, Chen, Jianhe, Guo, Li, Fleetwood, Andrew J, Hamilton, John A, Berchtold, Martin W, Panina, Svetlana

“…Osteoclast-associated receptor (OSCAR) is widely expressed on human myeloid cells. Collagen types (Col)I, II, and III have been described as OSCAR ligands, and…”
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Ca2+/calmodulin signaling in organismal aging and cellular senescence: Impact on human diseases by Berchtold, Martin W, Villalobo, Antonio

“…Molecular mechanisms of aging processes at the level of organisms and cells are in the focus of a large number of research laboratories. This research…”
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A note of caution for using calmodulin antibodies by Munk, Mads, Berchtold, Martin W.

“…Calmodulin (CaM) is a ubiquitous intracellular calcium receptor that regulates a plethora of cellular functions through interactions with target proteins. In…”
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Regulation of the Ligand-dependent Activation of the Epidermal Growth Factor Receptor by Calmodulin by Li, Hongbing, Panina, Svetlana, Kaur, Amandeep, Ruano, María J., Sánchez-González, Pablo, la Cour, Jonas M., Stephan, Alexander, Olesen, Uffe H., Berchtold, Martin W., Villalobo, Antonio

“…Calmodulin (CaM) is the major component of calcium signaling pathways mediating the action of various effectors. Transient increases in the intracellular…”
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Calmodulin as a protein linker and a regulator of adaptor/scaffold proteins by Villalobo, Antonio, Ishida, Hiroaki, Vogel, Hans J., Berchtold, Martin W.

“…Calmodulin (CaM) is a universal regulator for a huge number of proteins in all eukaryotic cells. Best known is its function as a calcium-dependent modulator of…”
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Proteins with calmodulin-like domains: structures and functional roles by Villalobo, Antonio, González-Muñoz, María, Berchtold, Martin W.

“…The appearance of modular proteins is a widespread phenomenon during the evolution of proteins. The combinatorial arrangement of different functional and/or…”
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Differential expression of the three independent CaM genes coding for an identical protein: Potential relevance of distinct mRNA stability by different codon usage by Munk, Mads, Villalobo, Eduardo, Villalobo, Antonio, Berchtold, Martin W.

“…•Evolution of three independent genes coding for an identical calmodulin protein.•Complex regulation of calmodulin expression.•Predicted regulation of…”
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ALG-2 knockdown in HeLa cells results in G2/M cell cycle phase accumulation and cell death by Høj, Berit R., la Cour, Jonas M., Mollerup, Jens, Berchtold, Martin W.

“…ALG-2 (apoptosis-linked gene-2 encoded protein) has been shown to be upregulated in a variety of human tumors questioning its previously assumed pro-apoptotic…”
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Up-Regulation of ALG-2 in Hepatomas and Lung Cancer Tissue by la Cour, Jonas M., Mollerup, Jens, Winding, Pernille, Tarabykina, Svetlana, Sehested, Maxwell, Berchtold, Martin W.

“…ALG-2 was isolated in a screen for proteins involved in programmed cell death and is the first Ca 2+-binding protein found to be directly involved in…”
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The chicken B cell line DT40: a novel tool for gene disruption experiments by Winding, Pernille, Berchtold, Martin W

“…The use of the chicken DT40 B cell line is increasing in popularity due to the ease with which it can be manipulated genetically. It offers a targeted to…”
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The impact of calmodulin on the cell cycle analyzed in a novel human cellular genetic system by Munk, Mads, Alcalde, Juan, Lorentzen, Lasse, Villalobo, Antonio, Berchtold, Martin W., Panina, Svetlana

“…[Display omitted] •A novel genetic system to investigate Calmodulin functions in a human cancer cell line.•Tet-off conditional Calmodulin expression provides a…”
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Calmodulin downregulation in conditional knockout HeLa cells inhibits cell migration by Alcalde, Juan, Munk, Mads, González-Muñoz, María, Panina, Svetlana, Berchtold, Martin W., Villalobo, Antonio

“…The study of calmodulin (CaM) functions in living cells has been tackled up to date using cell-permeant CaM inhibitors or interference-RNA methods. CaM…”
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The co-chaperone p23 is degraded by caspases and the proteasome during apoptosis by Mollerup, Jens, Berchtold, Martin W.

“…The heat shock protein 90 co-chaperone p23 has recently been shown to be up-regulated in cancer cells and down-regulated in atheroschlerotic plaques. We found…”
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The apoptosis linked gene ALG-2 is dysregulated in tumors of various origin and contributes to cancer cell viability by la Cour, Jonas M., Høj, Berit R., Mollerup, Jens, Simon, Ronald, Sauter, Guido, Berchtold, Martin W.

“…The apoptosis linked gene-2 (ALG-2), discovered as a proapoptotic calcium binding protein, has recently been found upregulated in lung cancer tissue indicating…”
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