Rapid differentiation of subarachnoid hemorrhage from traumatic lumbar puncture using the D-dimer assay

The D-dimer assay of 40 cerebral spinal fluid (CSF) samples accurately differentiated subarachnoid hemorrhage (SAH) from traumatic lumbar puncture. The D-dimer assay was positive in all six patients with subarachnoid hemorrhage. Negative D-dimer values were obtained in control groups of 14 patients...

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Bibliographic Details
Published in:	American journal of clinical pathology Vol. 93; no. 3; p. 403
Main Authors:	Lang, D T, Berberian, L B, Lee, S, Ault, M
Format:	Journal Article
Language:	English
Published:	England 01-03-1990
Subjects:	Antibodies, Monoclonal Diagnosis, Differential Erythrocyte Count Evaluation Studies as Topic Fibrin Fibrinogen Degradation Products - cerebrospinal fluid Hemorrhage - cerebrospinal fluid Hemorrhage - etiology Humans Latex Fixation Tests Predictive Value of Tests Spinal Puncture - adverse effects Subarachnoid Hemorrhage - cerebrospinal fluid Time Factors
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Summary:	The D-dimer assay of 40 cerebral spinal fluid (CSF) samples accurately differentiated subarachnoid hemorrhage (SAH) from traumatic lumbar puncture. The D-dimer assay was positive in all six patients with subarachnoid hemorrhage. Negative D-dimer values were obtained in control groups of 14 patients with hemorrhagic CSF secondary to traumatic lumbar puncture (LP) and in 20 patients with normal CSF. The D-dimer assay proved to be a better test than xanthochromia or the decline in erythrocyte count in sequentially collected tubes in differentiating subarachnoid hemorrhage from traumatic LP.
ISSN:	0002-9173
DOI:	10.1093/ajcp/93.3.403