Search Results - "Beranger, Guillaume E"
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Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo
Published in Nature communications (16-05-2019)“…T-cells play a crucial role in progression of autoimmunity, including vitiligo, yet the initial steps triggering their activation and tissue damage remain…”
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ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity
Published in Molecular cancer (07-01-2021)“…Resistances to immunotherapies remains a major hurdle towards a cure for melanoma in numerous patients. An increase in the mesenchymal phenotype and a loss of…”
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3
Oxytocin Reverses Ovariectomy-Induced Osteopenia and Body Fat Gain
Published in Endocrinology (Philadelphia) (01-04-2014)“…Osteoporosis and overweight/obesity constitute major worldwide public health burdens that are associated with aging. A high proportion of women develop…”
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Correction to: ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity
Published in Molecular cancer (27-01-2021)“…An amendment to this paper has been published and can be accessed via the original article…”
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The ω6-fatty acid, arachidonic acid, regulates the conversion of white to brite adipocyte through a prostaglandin/calcium mediated pathway
Published in Molecular metabolism (Germany) (01-12-2014)“…Abstract Objective Brite adipocytes are inducible energy-dissipating cells expressing UCP1 which appear within white adipose tissue of healthy adult…”
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Specific Expression of BMP2/4 Ortholog in Biomineralizing Tissues of Corals and Action on Mouse BMP Receptor
Published in Marine biotechnology (New York, N.Y.) (01-04-2009)“…Bone morphogenetic proteins (BMPs) are members of the transforming growth factor β superfamily, and have been identified by their ability to induce bone…”
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Differentiation of Human Adipose-Derived Stem Cells into "Brite" (Brown-in-White) Adipocytes
Published in Frontiers in endocrinology (Lausanne) (2011)“…It is well established now that adult humans possess active brown adipose tissue (BAT) which represents a potential pharmacological target to combat obesity…”
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Oxytocin reverses osteoporosis in a sex-dependent manner
Published in Frontiers in endocrinology (Lausanne) (19-05-2015)“…The increase of life expectancy has led to the increase of age-related diseases such as osteoporosis. Osteoporosis is characterized by bone weakening promoting…”
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9
Focus on cutaneous and uveal melanoma specificities
Published in Genes & development (15-04-2017)“…Cutaneous melanoma (CM) and uveal melanoma (UM) derive from cutaneous and uveal melanocytes that share the same embryonic origin and display the same cellular…”
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Poly(adp‐ribose) Polymerase‐1 Regulates Tracp Gene Promoter Activity During RANKL‐Induced Osteoclastogenesis
Published in Journal of bone and mineral research (01-04-2008)“…The Tracp gene encodes an acid phosphatase strongly upregulated during osteoclastogenesis on RANKL treatment. Using the mouse osteoclastic model RAW264.7, we…”
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Differential Binding of Poly(ADP‐Ribose) Polymerase‐1 and JunD/Fra2 Accounts for RANKL‐Induced Tcirg1 Gene Expression During Osteoclastogenesis
Published in Journal of bone and mineral research (01-07-2007)“…We studied Tcirg1 gene expression on RANKL‐induced osteoclastic differentiation of the mouse model RAW264.7 cells. We identified a mechanism involving PARP‐1…”
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RANKL Treatment Releases the Negative Regulation of the Poly(ADP‐Ribose) Polymerase‐1 on Tcirg1 Gene Expression During Osteoclastogenesis
Published in Journal of bone and mineral research (01-11-2006)“…The Tcirg1 gene encodes the osteoclast‐specific a3 isoform of the V‐ATPase a subunit. Using the mouse osteoclastic model RAW264.7 cells, we studied Tcirg1 gene…”
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Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells
Published in Cell death and differentiation (01-11-2018)“…HACE1 is an E3 ubiquitin ligase described as a tumour suppressor because HACE1 -knockout mice develop multi-organ, late-onset cancers and because HACE1…”
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Dual Covalent Inhibition of PKM and IMPDH Targets Metabolism in Cutaneous Metastatic Melanoma
Published in Cancer research (Chicago, Ill.) (15-07-2021)“…Overcoming acquired drug resistance is a primary challenge in cancer treatment. Notably, more than 50% of patients with BRAF cutaneous metastatic melanoma…”
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Let-7i-5p represses brite adipocyte function in mice and humans
Published in Scientific reports (27-06-2016)“…In response to cold or β3-adrenoreceptor stimulation brown adipose tissue (BAT) promotes non-shivering thermogenesis, leading to energy dissipation. BAT has…”
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In vitro brown and “brite”/“beige” adipogenesis: Human cellular models and molecular aspects
Published in Biochimica et biophysica acta (01-05-2013)“…Brown adipose tissue (BAT) has long been thought to be absent or very scarce in human adults so that its contribution to energy expenditure was not considered…”
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The K+ channel TASK1 modulates β‐adrenergic response in brown adipose tissue through the mineralocorticoid receptor pathway
Published in The FASEB journal (01-02-2016)“…Brown adipose tissue (BAT) is essential for adaptive thermogenesis and dissipation of caloric excess through the activity of uncoupling protein (UCP)‐1. BAT in…”
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Chondrogenic potential of stem cells derived from adipose tissue: A powerful pharmacological tool
Published in Biochemical and biophysical research communications (01-11-2013)“…•Chondrogenic potential of hMADS cells.•IL1-β and nicotine affect hMADS chondrogenesis.•hMADS cells represent a powerful tool for drug screening…”
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Monocytes differentiation upon treatment with a peptide corresponding to the C-terminus of activated T cell-expressed Tirc7 protein
Published in Journal of cellular physiology (01-08-2012)“…Atp6v0a3 gene encodes for two alternative products, Tirc7 and a3 proteins, which are differentially expressed in activated T cells and resorbing osteoclasts,…”
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Visfatin expression analysis in association with recruitment and activation of human and rodent brown and brite adipocytes
Published in Adipocyte (02-04-2016)“…Human brown adipocytes are able to burn fat and glucose and are now considered as a potential strategy to treat obesity, type 2 diabetes and metabolic…”
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