Search Results - "Bequette, B Wayne"

Algorithms for a Closed-Loop Artificial Pancreas: The Case for Model Predictive Control by Bequette, B. Wayne

“…The relative merits of model predictive control (MPC) and proportional-integral-derivative (PID) control are discussed, with the end goal of a closed-loop…”
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100 Years of insulin: A chemical engineering perspective by Bequette, B. Wayne

“…Insulin was isolated in 1921, with the first human patient treated in 1922, and large-scale production began in 1923. In this perspectives article I provide…”
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A Randomized Trial of a Home System to Reduce Nocturnal Hypoglycemia in Type 1 Diabetes by MAAHS, David M, CALHOUN, Peter, SLOVER, Robert, PAUL WADWA, R, WILSON, Darrell M, KOLLMAN, Craig, BECK, Roy W, BUCKINGHAM, Bruce A, PETER CHASE, H, HRAMIAK, Irene, LUM, John, CAMERON, Fraser, WAYNE BEQUETTE, B, AYE, Tandy, PAUL, Terri

“…Overnight hypoglycemia occurs frequently in individuals with type 1 diabetes and can result in loss of consciousness, seizure, or even death. We conducted an…”
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Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis by Buckingham, Bruce A, Raghinaru, Dan, Cameron, Fraser, Bequette, B Wayne, Chase, H Peter, Maahs, David M, Slover, Robert, Wadwa, R Paul, Wilson, Darrell M, Ly, Trang, Aye, Tandy, Hramiak, Irene, Clarson, Cheril, Stein, Robert, Gallego, Patricia H, Lum, John, Sibayan, Judy, Kollman, Craig, Beck, Roy W

“…Nocturnal hypoglycemia can cause seizures and is a major impediment to tight glycemic control, especially in young children with type 1 diabetes. We conducted…”
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A Hybrid Automata Approach for Monitoring the Patient in the Loop in Artificial Pancreas Systems by Beneyto, Aleix, Puig, Vicenç, Bequette, B. Wayne, Vehi, Josep

“…The use of automated insulin delivery systems has become a reality for people with type 1 diabetes (T1D), with several hybrid systems already on the market…”
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Predictive hyperglycemia and hypoglycemia minimization: In‐home double‐blind randomized controlled evaluation in children and young adolescents by Forlenza, Gregory P, Raghinaru, Dan, Cameron, Faye, Wayne Bequette, B, Peter Chase, H, Paul Wadwa, R, Maahs, David M, Jost, Emily, Ly, Trang T, Wilson, Darrell M, Norlander, Lisa, Ekhlaspour, Laya, Min, Hyojin, Clinton, Paula, Njeru, Nelly, Lum, John W, Kollman, Craig, Beck, Roy W, Buckingham, Bruce A

“…Objective The primary objective of this trial was to evaluate the feasibility, safety, and efficacy of a predictive hyperglycemia and hypoglycemia minimization…”
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Continuous Glucose Monitoring Enables the Detection of Losses in Infusion Set Actuation (LISAs) by Howsmon, Daniel P, Cameron, Faye, Baysal, Nihat, Ly, Trang T, Forlenza, Gregory P, Maahs, David M, Buckingham, Bruce A, Hahn, Juergen, Bequette, B Wayne

“…Reliable continuous glucose monitoring (CGM) enables a variety of advanced technology for the treatment of type 1 diabetes. In addition to artificial pancreas…”
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Challenges and recent progress in the development of a closed-loop artificial pancreas by Bequette, B. Wayne

“…Pursuit of a closed-loop artificial pancreas that automatically controls the blood glucose of individuals with type 1 diabetes has intensified during the past…”
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Hypoglycemia detection and prediction using continuous glucose monitoring-a study on hypoglycemic clamp data by Palerm, Cesar C, Bequette, B Wayne

“…The fear of hypoglycemia remains an important limiting factor in the ability of an individual with type 1 diabetes to tightly regulate glycemia. Continuous…”
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Observational process data analytics using causal inference by Yang, Shu, Bequette, B. Wayne

“…Voluminous process data are available with the paradigm shift toward smart manufacturing. However, most historical data are observational, containing noncausal…”
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Human-in-the-Loop Insulin Dosing by Bequette, B. Wayne

“…The last ten years of efforts in developing automated insulin dosing systems have led to one hybrid closed-loop device in the US market with more in the late…”
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Process Systems Engineering and the Human-in-The-Loop: The Smart Control Room by Ghosh, Sambit, Bequette, B. Wayne

“…For decades, studies have been conducted to understand and improve how humans and machines interact; yet, the process systems engineering field often focuses…”
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A New Meal Absorption Model for Artificial Pancreas Systems by Diamond, Travis, Cameron, Faye, Bequette, B. Wayne

“…Background: Artificial pancreas (AP) systems reduce the treatment burden of Type 1 Diabetes by automatically regulating blood glucose (BG) levels. While many…”
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A critical assessment of algorithms and challenges in the development of a closed-loop artificial pancreas by Bequette, B Wayne

“…The development of an artificial pancreas is placed in the context of the history of the field of feedback control systems, beginning with the water clock of…”
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Fault Tolerant Strategies for Automated Insulin Delivery Considering the Human Component: Current and Future Perspectives by Beneyto, Aleix, Bequette, B. Wayne, Vehi, Josep

“…Automated Insulin Delivery (AID) are systems developed for daily use by people with type 1 diabetes (T1D). To ensure the safety of users, it is essential to…”
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Decision making for safety and risk in healthcare and process systems by Sontakke, Mrunal, Okpanum, Jacinta, Yerimah, Lucky E., Rebmann, Andreas, Ghosh, Sambit, Wayne Bequette, B.

“…•Organization effect on safety and risk management.•Safety and Risk management in process industries and healthcare.•Human decision-making in safety critical…”
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Fault Detection and Safety in Closed-Loop Artificial Pancreas Systems by Bequette, B. Wayne

“…Continuous subcutaneous insulin infusion pumps and continuous glucose monitors enable individuals with type 1 diabetes to achieve tighter blood glucose control…”
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Continuous glucose monitoring: real-time algorithms for calibration, filtering, and alarms by Bequette, B Wayne

“…Algorithms for real-time use in continuous glucose monitors are reviewed, including calibration, filtering of noisy signals, glucose predictions for…”
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Hypo- and Hyperglycemic Alarms: Devices and Algorithms by Howsmon, Daniel, Bequette, B. Wayne

“…Soon after the discovery that insulin regulates blood glucose by Banting and Best in 1922, the symptoms and risks associated with hypoglycemia became widely…”
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Closed-Loop Control Without Meal Announcement in Type 1 Diabetes by Cameron, Faye M, Ly, Trang T, Buckingham, Bruce A, Maahs, David M, Forlenza, Gregory P, Levy, Carol J, Lam, David, Clinton, Paula, Messer, Laurel H, Westfall, Emily, Levister, Camilla, Xie, Yan Yan, Baysal, Nihat, Howsmon, Daniel, Patek, Stephen D, Bequette, B Wayne

“…A fully closed-loop insulin-only system was developed to provide glucose control in patients with type 1 diabetes without requiring announcement of meals or…”
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