Search Results - "Benzler, Jonas"

Photoperiodic and Diurnal Regulation of WNT Signaling in the Arcuate Nucleus of the Female Djungarian Hamster, Phodopus sungorus by Boucsein, Alisa, Benzler, Jonas, Hempp, Cindy, Stöhr, Sigrid, Helfer, Gisela, Tups, Alexander

“…The WNT pathway was shown to play an important role in the adult central nervous system. We previously identified the WNT pathway as a novel integration site…”
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Leptin rapidly improves glucose homeostasis in obese mice by increasing hypothalamic insulin sensitivity by Koch, Christiane, Augustine, Rachael A, Steger, Juliane, Ganjam, Goutham K, Benzler, Jonas, Pracht, Corinna, Lowe, Chrishanthi, Schwartz, Michael W, Shepherd, Peter R, Anderson, Greg M, Grattan, David R, Tups, Alexander

“…Obesity is associated with resistance to the actions of both leptin and insulin via mechanisms that remain incompletely understood. To investigate whether…”
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SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice by Sergi, Domenico, Campbell, Fiona M, Grant, Christine, Morris, Amanda C, Bachmair, Eva-Maria, Koch, Christiane, McLean, Fiona H, Muller, Aifric, Hoggard, Nigel, de Roos, Baukje, Porteiro, Begona, Boekschoten, Mark V, McGillicuddy, Fiona C, Kahn, Darcy, Nicol, Phyllis, Benzler, Jonas, Mayer, Claus-Dieter, Drew, Janice E, Roche, Helen M, Muller, Michael, Nogueiras, Ruben, Dieguez, Carlos, Tups, Alexander, Williams, Lynda M

“…Energy homeostasis is regulated by the hypothalamus but fails when animals are fed a high-fat diet (HFD), and leptin insensitivity and obesity develops. To…”
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Central inhibition of IKKβ/NF-κB signaling attenuates high-fat diet-induced obesity and glucose intolerance by Benzler, Jonas, Ganjam, Goutham K, Pretz, Dominik, Oelkrug, Rebecca, Koch, Christiane E, Legler, Karen, Stöhr, Sigrid, Culmsee, Carsten, Williams, Lynda M, Tups, Alexander

“…Metabolic inflammation in the central nervous system might be causative for the development of overnutrition-induced metabolic syndrome and related disorders,…”
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Hypothalamic WNT Signalling Is Impaired During Obesity and Reinstated by Leptin Treatment in Male Mice by Benzler, Jonas, Andrews, Zane B, Pracht, Corinna, Stöhr, Sigrid, Shepherd, Peter R, Grattan, David R, Tups, Alexander

“…The WNT pathway has been well characterized in embryogenesis and tumorigenesis. In humans, specific polymorphisms in the T cell-specific transcription factor 7…”
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“Insulin-like” effects of palmitate compromise insulin signalling in hypothalamic neurons by Benzler, Martin, Benzler, Jonas, Stoehr, Sigrid, Hempp, Cindy, Rizwan, Mohammed Z., Heyward, Phil, Tups, Alexander

“…Saturated fatty acids are implicated in the development of metabolic diseases, including obesity and type 2 diabetes. There is evidence, however, that…”
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Evidence That Diet-Induced Hyperleptinemia, but Not Hypothalamic Gliosis, Causes Ghrelin Resistance in NPY/AgRP Neurons of Male Mice by Briggs, Dana I, Lockie, Sarah H, Benzler, Jonas, Wu, Qunli, Stark, Romana, Reichenbach, Alex, Hoy, Andrew J, Lemus, Moyra B, Coleman, Harold A, Parkington, Helena C, Tups, Alex, Andrews, Zane B

“…High-fat diet (HFD) feeding causes ghrelin resistance in arcuate neuropeptide Y (NPY)/Agouti-related peptide neurons. In the current study, we investigated the…”
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Central Adiponectin Acutely Improves Glucose Tolerance in Male Mice by Koch, Christiane E, Lowe, Chrishanthi, Legler, Karen, Benzler, Jonas, Boucsein, Alisa, Böttiger, Gregor, Grattan, David R, Williams, Lynda M, Tups, Alexander

“…Adiponectin, an adipocyte-derived hormone, regulates glucose and lipid metabolism. It is also antiinflammatory. During obesity, adiponectin levels and…”
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Hypothalamic glycogen synthase kinase 3β has a central role in the regulation of food intake and glucose metabolism by Benzler, Jonas, Ganjam, Goutham K, Krüger, Manon, Pinkenburg, Olaf, Kutschke, Maria, Stöhr, Sigrid, Steger, Juliane, Koch, Christiane E, Ölkrug, Rebecca, Schwartz, Michael W, Shepherd, Peter R, Grattan, David R, Tups, Alexander

“…GSK3β (glycogen synthase kinase 3β) is a ubiquitous kinase that plays a key role in multiple intracellular signalling pathways, and increased GSK3β activity is…”
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Central Inhibition of IKK[Beta]/NF-[kappa]B Signaling Attenuates High-Fat Diet-Induced Obesity and Glucose Intolerance by Benzler, Jonas, Ganjam, Goutham K, Pretz, Dominik, Oelkrug, Rebecca, Koch, Christiane E, Legler, Karen, Stöhr, Sigrid, Culmsee, Carsten, Williams, Lynda M, Tups, Alexander

“…Metabolic inflammation in the central nervous system might be causative for the development of overnutrition-induced metabolic syndrome and related disorders,…”
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Overexpression of suppressor of cytokine signaling 3 in the arcuate nucleus of juvenile Phodopus sungorus alters seasonal body weight changes by Ganjam, Goutham K., Benzler, Jonas, Pinkenburg, Olaf, Boucsein, Alisa, Stöhr, Sigrid, Steger, Juliane, Culmsee, Carsten, Barrett, Perry, Tups, Alexander

“…The profound seasonal cycle in body weight exhibited by the Djungarian hamster ( Phodopus sungorus ) is associated with the development of hypothalamic leptin…”
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Central Regulation of Glucose Homeostasis by Tups, Alexander, Benzler, Jonas, Sergi, Domenico, Ladyman, Sharon R, Williams, Lynda M

“…The ability of the brain to directly control glucose levels in the blood independently of its effects on food intake and body weight has been known ever since…”
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