Search Results - "Benz, Caroline"
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Use of viral motif mimicry improves the proteome-wide discovery of human linear motifs
Published in Cell reports (Cambridge) (03-05-2022)“…Linear motifs have an integral role in dynamic cell functions, including cell signaling. However, due to their small size, low complexity, and frequent…”
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Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Published in Molecular systems biology (01-01-2022)“…Specific protein–protein interactions are central to all processes that underlie cell physiology. Numerous studies have together identified hundreds of…”
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3
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
Published in Nature communications (13-09-2023)“…The virus life cycle depends on host-virus protein-protein interactions, which often involve a disordered protein region binding to a folded protein domain…”
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Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
Published in Nature communications (19-11-2021)“…Viral proteins make extensive use of short peptide interaction motifs to hijack cellular host factors. However, most current large-scale methods do not…”
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Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
Published in Nature communications (26-04-2023)“…Viruses mimic host short linear motifs (SLiMs) to hijack and deregulate cellular functions. Studies of motif-mediated interactions therefore provide insight…”
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ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
Published in Nature communications (07-06-2024)“…The human methyltransferase and transcriptional coactivator MLL4 and its paralog MLL3 are frequently mutated in cancer. MLL4 and MLL3 monomethylate histone…”
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A Syntenin Inhibitor Blocks Endosomal Entry of SARS-CoV-2 and a Panel of RNA Viruses
Published in Viruses (01-10-2022)“…Viruses are dependent on host factors in order to efficiently establish an infection and replicate. Targeting the interactions of such host factors provides an…”
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B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
Published in iScience (18-11-2022)“…Met is an oncogene aberrantly activated in multiple cancers. Therefore, to better understand Met biology and its role in disease we applied the Mammalian…”
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God has a Plan: Moral Values and Beliefs of Christian Athletes in Competitive Sports
Published in Journal of human sport and exercise (01-01-2012)“…Christian athletes are people with specific and distinctive moral guidelines in everyday life as well as in competitive sports. No matter if they are competing…”
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Palliative Care Needs Within LTACH (GP755)
Published in Journal of pain and symptom management (01-06-2022)“…Outcomes. 1. Identify who qualifies for a long-term acute care hospital (LTACH) placement based on diagnosis, devices, etc. 2. Explain how a timely palliative…”
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Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase
Published in Nature chemical biology (01-11-2023)“…The modification of intracellular proteins with O-linked β- N -acetylglucosamine (O-GlcNAc) moieties is a highly dynamic process that spatiotemporally…”
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12
Mapping the MET Receptor Tyrosine Kinase Interactome using Mammalian Membrane Two Hybrid (MaMTH) system
Published in The FASEB journal (01-04-2020)“…Abstract only Background MET receptor tyrosine kinase is a growth factor receptor implicated in majority of cancers including lung, breast, pancreas, ovary and…”
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13
MLL4 binds TET3
Published in Structure (London) (06-06-2024)“…Human mixed lineage leukemia 4 (MLL4), also known as KMT2D, regulates cell type specific transcriptional programs through enhancer activation. Along with the…”
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14
Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
Published in Nature communications (2022)“…Viruses mimic host short linear motifs (SLiMs) to hijack and deregulate cellular functions. Studies of motif-mediated interactions therefore provide insight…”
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Valid methods for estimating children's sleep problems in clinical practice
Published in Acta Paediatrica (01-12-2014)Get full text
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God has a plan: moral values and beliefs of Christian athletes in competitive sports
Published in Journal of human sport and exercise (01-07-2012)“…Christian athletes are people with specific and distinctive moral guidelines in everyday life as well as in competitive sports. No matter if they are competing…”
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17
The Zurich 3-step concept for the management of behavioral sleep disorders in children: a before-and-after study
Published in Journal of clinical sleep medicine (15-03-2015)“…Several strategies have been found to be effective for the treatment of childhood behavioral sleep disorders. One which has yet to be evaluated is the Zurich…”
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Sleep physiology and its relevance for the management of behavioral sleep disorders in children
Published in Therapeutische Umschau (01-11-2014)“…Sleep problems are among the most frequent behavioural issues during childhood. This article highlights some of the most important aspects of children's sleep…”
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Developmental disorders in preschool children: an interdisciplinary approach
Published in Therapeutische Umschau (01-11-2013)“…Many children show developmental abnormalities in the first years of life. Thus, the primary care physician should know the procedures of developmental…”
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Primary nursing in ambulatory nursing
Published in Pflege aktuell (01-10-2004)Get more information
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