Search Results - "Bentley, Michael D"

Polyoxazoline: Chemistry, Properties, and Applications in Drug Delivery by Viegas, Tacey X, Bentley, Michael D, Harris, J. Milton, Fang, Zhihao, Yoon, Kunsang, Dizman, Bekir, Weimer, Rebecca, Mero, Anna, Pasut, Gianfranco, Veronese, Francesco M

“…Polyoxazoline polymers with methyl (PMOZ), ethyl (PEOZ), and propyl (PPOZ) side chains were prepared by the living cationic polymerization method and purified…”
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Clinical development of a poly(2-oxazoline) (POZ) polymer therapeutic for the treatment of Parkinson’s disease – Proof of concept of POZ as a versatile polymer platform for drug development in multiple therapeutic indications by Moreadith, Randall W., Viegas, Tacey X., Bentley, Michael D., Harris, J. Milton, Fang, Zhihao, Yoon, Kunsang, Dizman, Bekir, Weimer, Rebecca, Rae, Brendan P., Li, Xiuling, Rader, Christoph, Standaert, David, Olanow, Warren

“…[Display omitted] The potential of poly (2-oxazoline) or POZ to be a versatile and broad based platform for drug delivery with wide utility in multiple…”
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Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT) by Hann, Cheryl R., Bentley, Michael D., Vercnocke, Andrew, Ritman, Erik L., Fautsch, Michael P.

“…The site of outflow resistance leading to elevated intraocular pressure in primary open-angle glaucoma is believed to be located in the region of Schlemm’s…”
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Structural morphology of renal vasculature by Nordsletten, David A, Blackett, Shane, Bentley, Michael D, Ritman, Erik L, Smith, Nicolas P

“…An automatic segmentation technique has been developed and applied to two renal micro-computer tomography (CT) images. With the use of a 20-microm voxel…”
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Rotigotine polyoxazoline conjugate SER-214 provides robust and sustained antiparkinsonian benefit by Eskow Jaunarajs, Karen L., Standaert, David G., Viegas, Tacey X., Bentley, Michael D., Fang, Zhihao, Dizman, Bekir, Yoon, Kunsang, Weimer, Rebecca, Ravenscroft, Paula, Johnston, Tom H., Hill, Michael P., Brotchie, Jonathan M., Moreadith, Randall W.

“…ABSTRACT Currently available dopaminergic drugs such as levodopa and dopamine (DA) receptor agonists impart considerable improvement in Parkinson's disease…”
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Age-dependent renal cortical microvascular loss in female mice by Urbieta-Caceres, Victor H, Syed, Farhan A, Lin, Jing, Zhu, Xiang-Yang, Jordan, Kyra L, Bell, Caitlin C, Bentley, Michael D, Lerman, Amir, Khosla, Sundeep, Lerman, Lilach O

“…Renal function and blood flow decline during aging in association with a decrease in the number of intrarenal vessels, but if loss of estrogen contributes to…”
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Regional decreases in renal oxygenation during graded acute renal arterial stenosis: a case for renal ischemia by Warner, Lizette, Gomez, Sabas I, Bolterman, Rodney, Haas, John A, Bentley, Michael D, Lerman, Lilach O, Romero, Juan C

“…Ischemic nephropathy describes progressive renal failure, defined by significantly reduced glomerular filtration rate, and may be due to renal artery stenosis…”
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Tuning drug release from polyoxazoline-drug conjugates by Harris, J. Milton, Bentley, Michael D., Moreadith, Randall W., Viegas, Tacey X., Fang, Zhihao, Yoon, Kunsang, Weimer, Rebecca, Dizman, Bekir, Nordstierna, Lars

“…[Display omitted] Poly(2-oxazoline)-drug conjugates with drugs attached via releasable linkages are being developed for drug delivery. Such conjugates with…”
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Anatomic changes in Schlemm's canal and collector channels in normal and primary open-angle glaucoma eyes using low and high perfusion pressures by Hann, Cheryl R, Vercnocke, Andrew J, Bentley, Michael D, Jorgensen, Steven M, Fautsch, Michael P

“…To examine the anatomy of Schlemm's canal (SC) and collector channels (CCs) in normal human and primary open-angle glaucoma (POAG) eyes under low and high…”
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Anatomical Variation of Human Collector Channel Orifices by Bentley, Michael D, Hann, Cheryl R, Fautsch, Michael P

“…To examine the anatomical variation of normal human collector channel orifices and their relationship with Schlemm's canal. Ten human anterior segments fixed…”
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Evaluation of neural innervation in the human conventional outflow pathway distal to Schlemm's canal by Hann, Cheryl R., Bentley, Michael D., Vercnocke, Andrew, Roy Chowdhury, Uttio, Fautsch, Michael P.

“…The distal outflow pathway of the human eye consists of the outer wall of Schlemm's canal, collector channels, and the deep-scleral, mid-scleral and episcleral…”
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Antioxidant intervention prevents renal neovascularization in hypercholesterolemic pigs by CHADE, Alejandro R, BENTLEY, Michael D, XIANGYANG ZHU, RODRIGUEZ-PORCEL, Martin, NIEMEYER, Sara, AMORES-ARRIAGA, Beatriz, NAPOLI, Claudio, RITMAN, Erik L, LERMAN, Amir, LERMAN, Lilach O

“…Experimental hypercholesterolemia (HC) may lead to microvascular neovascularization, but the underlying pathogenic mechanism remains unclear. We tested the…”
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Antioxidant vitamins induce angiogenesis in the normal pig kidney by Daghini, Elena, Zhu, Xiang-Yang, Versari, Daniele, Bentley, Michael D, Napoli, Claudio, Lerman, Amir, Lerman, Lilach O

“…The effects of chronic supplementation with antioxidant vitamins on angiogenesis are controversial. The aim of the present study was to evaluate in kidneys of…”
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Enhanced renal cortical vascularization in experimental hypercholesterolemia by Bentley, Michael D., Rodriguez-Porcel, Martin, Lerman, Amir, Sarafov, Mirit Hershman, Romero, J. Carlos, Pelaez, Laura I., Grande, Joseph P., Ritman, Erik L., Lerman, Lilach O.

“…Enhanced renal cortical vascularization in experimental hypercholesterolemia. Experimental hypercholesterolemia is associated with pro-inflammatory changes and…”
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Three-dimensional microcomputed tomography of renal vasculature in rats by GARCIA-SANZ, A, RODRIGUEZ-BARBERO, A, BENTLEY, M. D, RITMAN, E. L, ROMERO, J. C

“…Current microscopic methods to view renal microvasculature reveal only a very limited portion of the total renal volume. Identification of connectivity for…”
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Effect of losartan on renal microvasculature during chronic inhibition of nitric oxide visualized by micro-CT by Fortepiani, Loudes A, Ruiz, M Clara Ortiz, Passardi, Federico, Bentley, Michael D, Garcia-Estan, Joaquin, Ritman, Erik L, Romero, J Carlos

“…Chronic inhibition of nitric oxide (NO) synthase with the competitive l-arginine analog NG-nitro-l-arginine methyl ester (l-NAME) leads to an elevated systemic…”
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Cortical Microvascular Remodeling in the Stenotic Kidney: Role of Increased Oxidative Stress by Zhu, Xiang-Yang, Chade, Alejandro R, Rodriguez-Porcel, Martin, Bentley, Michael D, Ritman, Erik L, Lerman, Amir, Lerman, Lilach O

“…OBJECTIVE—Mechanisms of renal injury distal to renal artery stenosis (RAS) remain unclear. We tested the hypothesis that it involves microvascular remodeling…”
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Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia by ZHU, Xiang-Yang, RODRIGUEZ-PORCEL, Martin, BENTLEY, Michael D, CHADE, Alejandro R, SICA, Vincenzo, NAPOLI, Claudio, CAPLICE, Noel, RITMAN, Erik L, LERMAN, Amir, LERMAN, Lilach O

“…Hypercholesterolemia (HC) and atherosclerosis can elicit oxidative stress, coronary endothelial dysfunction, and myocardial ischemia, which may induce…”
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The use of microcomputed tomography to study microvasculature in small rodents by Bentley, Michael D, Ortiz, Maria C, Ritman, Erik L, Romero, J Carlos

“…Appropriate nephron function is dependent on the intrarenal arrangement of blood vessels. The preferred and primary means to study the architecture of…”
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Isolation of Betulin and Rearrangement to Allobetulin. A Biomimetic Natural Product Synthesis by Green, Brian, Bentley, Michael D, Chung, Bong Y, Lynch, Nicholas G, Jensen, Bruce L

“…The triterpenes are a diverse class of widely distributed natural products derived from squalene. Various cyclization and subsequent rearrangement reactions…”
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