Search Results - "Benstoem, Carina"

Selenium and its supplementation in cardiovascular disease--what do we know? by Benstoem, Carina, Goetzenich, Andreas, Kraemer, Sandra, Borosch, Sebastian, Manzanares, William, Hardy, Gil, Stoppe, Christian

“…The trace element selenium is of high importance for many of the body's regulatory and metabolic functions. Balanced selenium levels are essential, whereas…”
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Observational study of missing SOFA score data frequency in RCTs relative to ICU length of stay by Molinnus, Denise, Beulertz, Michael, Bickenbach, Johannes, Marx, Gernot, Benstoem, Carina

“…The Sequential Organ Failure Assessment, also known as SOFA score, was introduced to assess organ dysfunction of critical ill patients. However, understanding…”
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Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine by Reintam Blaser, Annika, Preiser, Jean-Charles, Fruhwald, Sonja, Wilmer, Alexander, Wernerman, Jan, Benstoem, Carina, Casaer, Michael P, Starkopf, Joel, van Zanten, Arthur, Rooyackers, Olav, Jakob, Stephan M, Loudet, Cecilia I, Bear, Danielle E, Elke, Gunnar, Kott, Matthias, Lautenschläger, Ingmar, Schäper, Jörn, Gunst, Jan, Stoppe, Christian, Nobile, Leda, Fuhrmann, Valentin, Berger, Mette M, Oudemans-van Straaten, Heleen M, Arabi, Yaseen M, Deane, Adam M

“…Gastrointestinal (GI) dysfunction is frequent in the critically ill but can be overlooked as a result of the lack of standardization of the diagnostic and…”
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Early versus late tracheostomy in critically ill COVID-19 patients by Szafran, Agnieszka, Dahms, Karolina, Ansems, Kelly, Skoetz, Nicole, Monsef, Ina, Breuer, Thomas, Benstoem, Carina

“…The role of early tracheostomy as an intervention for critically ill COVID-19 patients is unclear. Previous reports have described prolonged intensive care…”
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Effects of iNOS in Hepatic Warm Ischaemia and Reperfusion Models in Mice and Rats: A Systematic Review and Meta-Analysis by Nakatake, Richi, Schulz, Mareike, Kalvelage, Christina, Benstoem, Carina, Tolba, René H.

“…Warm ischaemia is usually induced by the Pringle manoeuver (PM) during hepatectomy. Currently, there is no widely accepted standard protocol to minimise…”
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Anakinra for the treatment of COVID-19 patients: a systematic review and meta-analysis by Dahms, Karolina, Mikolajewska, Agata, Ansems, Kelly, Metzendorf, Maria-Inti, Benstoem, Carina, Stegemann, Miriam

“…At the end of 2021, the European Medicines Agency (EMA) expanded its approval for the recombinant human interleukin-1 (IL-1) receptor antagonist Anakinra for…”
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Role of nutrition support in adult cardiac surgery: a consensus statement from an International Multidisciplinary Expert Group on Nutrition in Cardiac Surgery by Stoppe, Christian, Goetzenich, Andreas, Whitman, Glenn, Ohkuma, Rika, Brown, Trish, Hatzakorzian, Roupen, Kristof, Arnold, Meybohm, Patrick, Mechanick, Jefferey, Evans, Adam, Yeh, Daniel, McDonald, Bernard, Chourdakis, Michael, Jones, Philip, Barton, Richard, Tripathi, Ravi, Elke, Gunnar, Liakopoulos, Oliver, Agarwala, Ravi, Lomivorotov, Vladimir, Nesterova, Ekaterina, Marx, Gernot, Benstoem, Carina, Lemieux, Margot, Heyland, Daren K

“…Nutrition support is a necessary therapy for critically ill cardiac surgery patients. However, conclusive evidence for this population, consisting of…”
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Vitamin C to Improve Organ Dysfunction in Cardiac Surgery Patients-Review and Pragmatic Approach by Hill, Aileen, Wendt, Sebastian, Benstoem, Carina, Neubauer, Christina, Meybohm, Patrick, Langlois, Pascal, Adhikari, Neill Kj, Heyland, Daren K, Stoppe, Christian

“…The pleiotropic biochemical and antioxidant functions of vitamin C have sparked recent interest in its application in intensive care. Vitamin C protects…”
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Standardized pharmacological management of delirium after on-pump cardiac surgery reduces ICU stay and ventilation in a retrospective pre-post study by Deininger, Matthias Manfred, Schnitzler, Stefan, Benstoem, Carina, Simon, Tim-Philipp, Marx, Gernot, Panagiotidis, Despina, Ziles, Dmitrij, Schnoering, Heike, Karasimos, Evangelos, Breuer, Thomas

“…Cardiac surgery patients not only undergo a highly invasive procedure but are at risk for a diversity of postoperative complications. Up to 53% of these…”
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A core outcome set for adult cardiac surgery trials: A consensus study by Benstoem, Carina, Moza, Ajay, Meybohm, Patrick, Stoppe, Christian, Autschbach, Rüdiger, Devane, Declan, Goetzenich, Andreas

“…Invasive off- or on-pump cardiac surgery (elective and emergency procedures, excluding transplants are routinely performed to treat complications of ischaemic…”
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Evaluating outcomes used in cardiothoracic surgery interventional research: a systematic review of reviews to develop a core outcome set by Benstoem, Carina, Moza, Ajay, Autschbach, Rüdiger, Stoppe, Christian, Goetzenich, Andreas

“…When planning clinical trials, it is a key element to choose appropriate outcomes that ensure the comparability of effects of interventions in ways that…”
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Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis by Hill, Aileen, Clasen, Kai C, Wendt, Sebastian, Majoros, Ádám G, Stoppe, Christian, Adhikari, Neill K J, Heyland, Daren K, Benstoem, Carina

“…Cardiac surgery is associated with oxidative stress and systemic inflammation, which both contribute to postoperative organ dysfunction. Vitamin C is a…”
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An Innovative Telemedical Network to Improve Infectious Disease Management in Critically Ill Patients and Outpatients (TELnet@NRW): Stepped-Wedge Cluster Randomized Controlled Trial by Marx, Gernot, Greiner, Wolfgang, Juhra, Christian, Elkenkamp, Svenja, Gensorowsky, Daniel, Lemmen, Sebastian, Englbrecht, Jan, Dohmen, Sandra, Gottschalk, Antje, Haverkamp, Miriam, Hempen, Annette, Flügel-Bleienheuft, Christian, Bause, Daniela, Schulze-Steinen, Henna, Rademacher, Susanne, Kistermann, Jennifer, Hoch, Stefan, Beckmann, Hans-Juergen, Lanckohr, Christian, Lowitsch, Volker, Peine, Arne, Juzek-Kuepper, Fabian, Benstoem, Carina, Sperling, Kathrin, Deisz, Robert

“…Evidence-based infectious disease and intensive care management is more relevant than ever. Medical expertise in the two disciplines is often geographically…”
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Ivabradine for the Therapy of Chronic Stable Angina Pectoris: a Systematic Review and Meta-Analysis by Kalvelage, Christina, Stoppe, Christian, Marx, Nikolaus, Marx, Gernot, Benstoem, Carina

“…BACKGROUND AND OBJECTIVESCoronary artery disease (CAD) is the number one cause of death worldwide. The If channel inhibitor ivabradine serves as second line…”
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Effects of hypercapnia versus normocapnia during general anesthesia on outcomes: a systematic review and meta-analysis by Petran, Jan, Ansems, Kelly, Rossaint, Rolf, Marx, Gernot, Kalvelage, Christina, Kopp, Rüdger, Benstoem, Carina, Brülls, Christian

“…The effect of mild changes in CO2 levels to organ perfusion and tissue inflammation are well known, whereas an influence of hypercapnia under general…”
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Retrospective Analysis of Air Handling by Contemporary Oxygenators in the Setting of Cardiac Surgery by Benstoem, Carina, Christian, Bleilevens, Ralf, Borchardt, Christian, Stoppe, Andreas, Goetzenich, Ruedriger, Autschbach, Thomas, Breuer

“…Purpose: Cardiac surgery with the use of extracorporeal circulation is associated with a significant risk for gaseous microemboli (GME) despite excellent…”
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Evaluation of Persistent Organ Dysfunction Plus Death As a Novel Composite Outcome in Cardiac Surgical Patients by Stoppe, Christian, MD, McDonald, Bernard, MD, PhD, Benstoem, Carina, MSc, Elke, Gunnar, MD, Meybohm, Patrick, MD, Whitlock, Richard, MD, Fremes, Stephen, MD, Fowler, Robert, MD, Lamarche, Yoan, MD, Jiang, Xuran, MD, Day, Andrew G., MD, Heyland, Daren K., MD

“…Objectives Validated composite outcomes after complicated cardiac surgery are poorly established. Therefore, the authors evaluated a novel composite endpoint,…”
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Decision-Making Authority During Tele-ICU Care Reduces Mortality and Length of Stay—A Systematic Review and Meta-Analysis by Kalvelage, Christina, Rademacher, Susanne, Dohmen, Sandra, Marx, Gernot, Benstoem, Carina

“…Although the current coronavirus disease 2019 pandemic demonstrates the urgent need for the integration of tele-ICUs, there is still a lack of uniform…”
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Remdesivir for the treatment of COVID-19 by Ansems, Kelly, Grundeis, Felicitas, Dahms, Karolina, Mikolajewska, Agata, Thieme, Volker, Piechotta, Vanessa, Metzendorf, Maria-Inti, Stegemann, Miriam, Benstoem, Carina, Fichtner, Falk

“…Remdesivir is an antiviral medicine with properties to inhibit viral replication of SARS-CoV-2. Positive results from early studies attracted media attention…”
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Remdesivir for the treatment of COVID-19 by Grundeis, Felicitas, Ansems, Kelly, Dahms, Karolina, Thieme, Volker, Metzendorf, Maria-Inti, Skoetz, Nicole, Benstoem, Carina, Mikolajewska, Agata, Griesel, Mirko, Fichtner, Falk, Stegemann, Miriam

“…Remdesivir is an antiviral medicine approved for the treatment of mild-to-moderate coronavirus disease 2019 (COVID-19). This led to widespread implementation,…”
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