A new isoflavonoid derivative, evaluation of the antioxidant capacity and phenolic content of Genista lobelii DC

The phytochemical investigation of both chloroform and ethyl acetate extracts of Genista lobelii DC from an Algerian endemic plant led to the isolation of a new isoflavonoid Aspalathoidin compound (1) and nine known compounds (laburnetin, isokaempferide, retamasin B, ephedrodin, sakuretin, isoprunet...

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Published in:	Natural product research Vol. 38; no. 21; pp. 3842 - 3847
Main Authors:	Boukaabache, Rabia, Kerkatou, Wafa, Bensouici, Chaouki, Benayache, Fadila, Boumaza, Ouahiba
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 01-11-2024 Taylor & Francis Ltd
Subjects:	Acetic acid antioxidant activities Antioxidants Antioxidants - chemistry Antioxidants - pharmacology Butanol Chloroform Chromatography, High Pressure Liquid Endemic plants Ethyl acetate fabaceae Flavonoids Flavonoids - analysis Flavonoids - chemistry Genista Genista - chemistry Genista lobelii DC Genistein HPLC/UV-Visible Isoflavones - analysis Isoflavones - chemistry Liquid chromatography Molecular Structure Phenolic compounds Phenols Phenols - analysis Phenols - chemistry Plant extracts Plant Extracts - chemistry total phenolic antioxidant activities Genista lobelii DC total phenolic HPLC/UV-Visible fabaceae
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Summary:	The phytochemical investigation of both chloroform and ethyl acetate extracts of Genista lobelii DC from an Algerian endemic plant led to the isolation of a new isoflavonoid Aspalathoidin compound (1) and nine known compounds (laburnetin, isokaempferide, retamasin B, ephedrodin, sakuretin, isoprunetin, genistein −7-O-β-glucoside, derrone-4′-O-methyl ether and eriodictyol-7,3′-dimethylether). Twelve phenolic compounds were identified in ethyl acetate and n-butanol extracts through a qualitative investigation of phenolic compounds using HPLC. Finally, both extracts were estimated for their phenolic and flavonoid contents as well as the evaluation of their antioxidant activity using five different assays DPPH, CUPRAC, ABTS, GOR and the sun protection factor SPF was determined as an index of the photoprotective capacity of the G.lobelii DC extracts. The extract of chloroform and ethyl acetate has good antioxidant and includes significant levels of phenolic and flavonoid components.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1478-6419 1478-6427 1478-6427
DOI:	10.1080/14786419.2023.2261073