Search Results - "Benson, Merrill"

Liver transplantation and transthyretin amyloidosis by Benson, Merrill D.

“…Liver transplantation as a specific treatment of transthyretin amyloidosis was first performed in 1990. The rationale for this treatment was that removal of…”
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Diagnosis, Prognosis, and Therapy of Transthyretin Amyloidosis by Gertz, Morie A., MD, Benson, Merrill D., MD, Dyck, Peter J., MD, Grogan, Martha, MD, Coelho, Terresa, MD, Cruz, Marcia, MD, Berk, John L., MD, Plante-Bordeneuve, Violaine, MD, Schmidt, Hartmut H.J., MD, Merlini, Giampaolo, MD

“…Abstract Transthyretin amyloidosis is a fatal disorder that is characterized primarily by progressive neuropathy and cardiomyopathy. It occurs in both a mutant…”
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Amyloid nomenclature 2020: update and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee by Benson, Merrill D., Buxbaum, Joel N., Eisenberg, David S., Merlini, Giampaolo, Saraiva, Maria J. M., Sekijima, Yoshiki, Sipe, Jean D., Westermark, Per

“…The ISA Nomenclature Committee met electronically before and directly after the XVII ISA International Symposium on Amyloidosis, which, unfortunately, had to…”
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Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee by Benson, Merrill D., Buxbaum, Joel N., Eisenberg, David S., Merlini, Giampaolo, Saraiva, Maria J. M., Sekijima, Yoshiki, Sipe, Jean D., Westermark, Per

“…The nomenclature committee of the International Society of Amyloidosis (ISA) meets every second year to discuss and formulate recommendations. The conclusions…”
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Amyloid fibril proteins and amyloidosis: chemical identification and clinical classification International Society of Amyloidosis 2016 Nomenclature Guidelines by Sipe, Jean D., Benson, Merrill D., Buxbaum, Joel N., Ikeda, Shu-ichi, Merlini, Giampaolo, Saraiva, Maria J. M., Westermark, Per

“…The Nomenclature Committee of the International Society of Amyloidosis (ISA) met during the XVth Symposium of the Society, 3 July-7 July 2016, Uppsala, Sweden,…”
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Nomenclature 2014: Amyloid fibril proteins and clinical classification of the amyloidosis by Sipe, Jean D., Benson, Merrill D., Buxbaum, Joel N., Ikeda, Shu-ichi, Merlini, Giampaolo, Saraiva, Maria J. M., Westermark, Per

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Inotersen therapy of transthyretin amyloid cardiomyopathy by Dasgupta, Noel R., Rissing, Stacy M., Smith, Jessica, Jung, Jeesun, Benson, Merrill D.

“…Background: Cardiomyopathy is a major cause of death in patients with systemic transthyretin amyloidosis. Long term effect of therapy designed to inhibit…”
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The molecular biology and clinical features of amyloid neuropathy by Benson, Merrill D., Kincaid, John C.

“…Neuropathy is often a major manifestation of systemic amyloidosis. It is most frequently seen in patients with hereditary transthyretin (TTR) amyloidosis, but…”
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Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition by Saelices, Lorena, Chung, Kevin, Lee, Ji H., Cohn, Whitaker, Whitelegge, Julian P., Benson, Merrill D., Eisenberg, David S.

“…Each of the 30 human amyloid diseases is associated with the aggregation of a particular precursor protein into amyloid fibrils. In transthyretin amyloidosis…”
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Guidelines and new directions in the therapy and monitoring of ATTRv amyloidosis by Ando, Yukio, Adams, David, Benson, Merrill D., Berk, John L., Planté-Bordeneuve, Violaine, Coelho, Teresa, Conceição, Isabel, Ericzon, Bo-Göran, Obici, Laura, Rapezzi, Claudio, Sekijima, Yoshiki, Ueda, Mitsuharu, Palladini, Giovanni, Merlini, Giampaolo

“…The recent approval of three drugs for the treatment of amyloid transthyretin (ATTR) amyloidosis, both hereditary and wild-type, has opened a new era in the…”
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Inotersen treatment for ATTR amyloidosis by Benson, Merrill D.

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POTENTIAL REVERSAL OF TRANSTHYRETIN AMYLOID CARDIOMYOPATHY WITH TTR SPECIFIC ANTISENSE OLIGONUCLEOTIDE THERAPY by Dasgupta, Noel Rakhi, Benson, Merrill D.

“…In the majority of patients with ATTR cardiomyopathy death is due to progressive cardiac failure from restrictive cardiomyopathy. Since TTR is synthesized…”
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Detection of Circulating Transthyretin Amyloid Aggregates in Plasma: A Novel Biomarker for Transthyretin Amyloidosis by Pedretti, Rose, Wang, Lanie, Hanna, Mazen, Benson, Merrill D, Grodin, Justin L, Tang, W H Wilson, Masri, Ahmad, Saelices, Lorena

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Progression of transthyretin amyloid neuropathy after liver transplantation by LIEPNIEKS, Juris J, ZHANG, Lucy Q, BENSON, Merrill D

“…To biochemically characterize peripheral nerve amyloid in subjects with transthyretin (TTR) amyloidosis and assess effect of orthotopic liver transplantation…”
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Safety and efficacy of a TTR specific antisense oligonucleotide in patients with transthyretin amyloid cardiomyopathy by Benson, Merrill D., Dasgupta, Noel R., Rissing, Stacy M., Smith, Jessica, Feigenbaum, Harvey

“…Objectives: Cardiomyopathy is a major cause of death in both the hereditary form of transthyretin (TTR) amyloidosis and the sporadic late-age-onset…”
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Editorial Commentary: Advances in transthyretin amyloid cardiomyopathy by Benson, Merrill D., Dasgupta, Noel R.

“…First described as an autosomal dominant inherited trait with adult onset peripheral neuropathy as the major clinical manifestation, it is now recognized as a…”
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LECT2 amyloidosis by Benson, Merrill D.

“…LECT2 amyloidosis is the latest systemic type of amyloidosis to be described. It was discovered in patients with nephrotic syndrome and renal failure and is…”
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Transthyretin amyloidosis: a little history of hereditary amyloidosis by Benson, Merrill D.

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Hereditary systemic immunoglobulin light-chain amyloidosis by Benson, Merrill D., Liepnieks, Juris J., Kluve-Beckerman, Barbara

“…Several members of a family died from renal failure as a result of systemic amyloidosis. Extensive studies to detect previously documented gene mutations…”
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Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides by Ackermann, Elizabeth J., Guo, Shuling, Benson, Merrill D., Booten, Sheri, Freier, Sue, Hughes, Steven G., Kim, Tae-Won, Jesse Kwoh, T., Matson, John, Norris, Dan, Yu, Rosie, Watt, Andy, Monia, Brett P.

“…Transthyretin amyloidosis (ATTR amyloidosis) is a rare disease that results from the deposition of misfolded transthyretin (TTR) protein from the plasma into…”
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