Search Results - "Benson, Meredith"

A Secreted Bacterial Protease Tailors the Staphylococcus aureus Virulence Repertoire to Modulate Bone Remodeling during Osteomyelitis by Cassat, James E., Hammer, Neal D., Campbell, J. Preston, Benson, Meredith A., Perrien, Daniel S., Mrak, Lara N., Smeltzer, Mark S., Torres, Victor J., Skaar, Eric P.

“…Osteomyelitis is a common manifestation of invasive Staphylococcus aureus infection. Pathogen-induced bone destruction limits antimicrobial penetration to the…”
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Staphylococcus aureus Elaborates Leukocidin AB To Mediate Escape from within Human Neutrophils by DuMont, Ashley L, Yoong, Pauline, Surewaard, Bas G J, Benson, Meredith A, Nijland, Reindert, van Strijp, Jos A G, Torres, Victor J

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Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo by Alonzo III, Francis, Benson, Meredith A., Chen, John, Novick, Richard P., Shopsin, Bo, Torres, Victor J.

“…Summary Bloodstream infection with Staphylococcus aureus is common and can be fatal. However, virulence factors that contribute to lethality in S. aureus…”
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Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element by Benson, Meredith A., Ohneck, Elizabeth A., Ryan, Chanelle, Alonzo, Francis, Smith, Hannah, Narechania, Apurva, Kolokotronis, Sergios‐Orestis, Satola, Sarah W., Uhlemann, Anne‐Catrin, Sebra, Robert, Deikus, Gintaras, Shopsin, Bo, Planet, Paul J., Torres, Victor J.

“…Summary Staphylococcus aureus has evolved as a pathogen that causes a range of diseases in humans. There are two dominant modes of evolution thought to explain…”
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A Comparison of Linear and Cyclic Peptoid Oligomers as Potent Antimicrobial Agents by Huang, Mia Lace, Shin, Sung Bin Y., Benson, Meredith A., Torres, Victor J., Kirshenbaum, Kent

“…We investigated the antimicrobial activities of N‐substituted glycine “peptoid” oligomers incorporating cationic and hydrophobic side chains. Head‐to‐tail…”
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Rot and SaeRS Cooperate To Activate Expression of the Staphylococcal Superantigen-Like Exoproteins by Benson, Meredith A, Lilo, Sarit, Nygaard, Tyler, Voyich, Jovanka M, Torres, Victor J

“…Staphylococcus aureus is a significant human pathogen that is capable of infecting a wide range of host tissues. This bacterium is able to evade the host…”
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Rot is a key regulator of Staphylococcus aureus biofilm formation by Mootz, Joe M., Benson, Meredith A., Heim, Cortney E., Crosby, Heidi A., Kavanaugh, Jeffrey S., Dunman, Paul M., Kielian, Tammy, Torres, Victor J., Horswill, Alexander R.

“…Summary Staphylococcus aureus is a significant cause of chronic biofilm infections on medical implants. We investigated the biofilm regulatory cascade and…”
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Nfu facilitates the maturation of iron‐sulfur proteins and participates in virulence in Staphylococcus aureus by Mashruwala, Ameya A., Pang, Yun Y., Rosario‐Cruz, Zuelay, Chahal, Harsimranjit K., Benson, Meredith A., Mike, Laura A., Skaar, Eric P., Torres, Victor J., Nauseef, William M., Boyd, Jeffrey M.

“…Summary The acquisition and metabolism of iron (Fe) by the human pathogen Staphylococcus aureus is critical for disease progression. S. aureus requires Fe to…”
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Amphiphilic Cyclic Peptoids That Exhibit Antimicrobial Activity by Disrupting Staphylococcus aureus Membranes by Huang, Mia L., Benson, Meredith A., Shin, Sung Bin Y., Torres, Victor J., Kirshenbaum, Kent

“…There is a significant unmet need for new antimicrobial agents that can address antimicrobial resistance. One promising group of antimicrobials is the…”
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Roles of Staphylococcus aureus Mnh1 and Mnh2 Antiporters in Salt Tolerance, Alkali Tolerance, and Pathogenesis by Vaish, Manisha, Price-Whelan, Alexa, Reyes-Robles, Tamara, Liu, Jun, Jereen, Amyeo, Christie, Stephanie, Alonzo, 3rd, Francis, Benson, Meredith A, Torres, Victor J, Krulwich, Terry A

“…has three types of cation/proton antiporters. The type 3 family includes two ultisubunit a / (Mnh) antiporters, Mnh1 and Mnh2. These antiporters are clusters…”
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Transcriptional profiling of Staphylococcus aureus during growth in 2 M NaCl leads to clarification of physiological roles for Kdp and Ktr K+ uptake systems by Price-Whelan, Alexa, Poon, Chun Kit, Benson, Meredith A, Eidem, Tess T, Roux, Christelle M, Boyd, Jeffrey M, Dunman, Paul M, Torres, Victor J, Krulwich, Terry A

“…Staphylococcus aureus exhibits an unusually high level of osmotolerance and Na(+) tolerance, properties that support survival in various host niches and in…”
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Staphylococcus aureus regulates the expression and production of the staphylococcal superantigen‐like secreted proteins in a Rot‐dependent manner by Benson, Meredith A., Lilo, Sarit, Wasserman, Gregory A., Thoendel, Matthew, Smith, Amanda, Horswill, Alexander R., Fraser, John, Novick, Richard P., Shopsin, Bo, Torres, Victor J.

“…Summary Staphylococcus aureus overproduces a subset of immunomodulatory proteins known as the staphylococcal superantigen‐like proteins (Ssls) under conditions…”
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Membrane damage elicits an immunomodulatory program in Staphylococcus aureus by Attia, Ahmed S, Benson, Meredith A, Stauff, Devin L, Torres, Victor J, Skaar, Eric P

“…The Staphylococcus aureus HrtAB system is a hemin-regulated ABC transporter composed of an ATPase (HrtA) and a permease (HrtB) that protect S. aureus against…”
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Characterization of SSR42, a Novel Virulence Factor Regulatory RNA That Contributes to the Pathogenesis of a Staphylococcus aureus USA300 Representative by MORRISON, John M, MILLER, Eric W, BENSON, Meredith A, ALONZO, Francis, YOONG, Pauline, TORRES, Victor J, HINRICHS, Steven H, DUNMAN, Paul M

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Structure-Based Functional Characterization of Repressor of Toxin (Rot), a Central Regulator of Staphylococcus aureus Virulence by Killikelly, April, Benson, Meredith A, Ohneck, Elizabeth A, Sampson, Jared M, Jakoncic, Jean, Spurrier, Brett, Torres, Victor J, Kong, Xiang-Peng

“…Staphylococcus aureus is responsible for a large number of diverse infections worldwide. In order to support its pathogenic lifestyle, S. aureus has to…”
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Probing the activity of NTHL1 orthologs by targeting conserved amino acid residues by Robey-Bond, Susan M., Benson, Meredith A., Barrantes-Reynolds, Ramiro, Bond, Jeffrey P., Wallace, Susan S.

“…•E. coli Asp44 plays a different role than its homologous residue in human NTHL1.•hNTHL1 Gln287 in involved in opposite base specificity as well as…”
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Intracellular Localization of Cthrc1 Characterizes Differentiated Smooth Muscle by LeClair, Renée J, Wang, Qiaozeng, Benson, Meredith A, Prudovsky, Igor, Lindner, Volkhard

“…OBJECTIVE—We recently reported expression of collagen triple helix repeat containing-1 (Cthrc1) in injured arteries and proteolytic cleavage of Cthrc1 in…”
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High Rate of Complications With Early Conversion Hip Arthroplasty Following Fracture Treatment by Grayson, Whisper, Eikani, Carlo, Benson, Meredith, Jozefowski, Nicolas, Brown, Nicholas M.

“…Background: Conversion total hip arthroplasty (THA) is associated with higher rates of complications compared with primary THA, with prior surgical fixation of…”
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R ot is a key regulator of S taphylococcus aureus biofilm formation by Mootz, Joe M., Benson, Meredith A., Heim, Cortney E., Crosby, Heidi A., Kavanaugh, Jeffrey S., Dunman, Paul M., Kielian, Tammy, Torres, Victor J., Horswill, Alexander R.

“…Summary S taphylococcus aureus is a significant cause of chronic biofilm infections on medical implants. We investigated the biofilm regulatory cascade and…”
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Nfu facilitates the maturation of iron‐sulfur proteins and participates in virulence in S taphylococcus aureus by Mashruwala, Ameya A., Pang, Yun Y., Rosario‐Cruz, Zuelay, Chahal, Harsimranjit K., Benson, Meredith A., Mike, Laura A., Skaar, Eric P., Torres, Victor J., Nauseef, William M., Boyd, Jeffrey M.

“…Summary The acquisition and metabolism of iron ( Fe ) by the human pathogen S taphylococcus aureus is critical for disease progression. S . aureus requires Fe…”
Get full text