Search Results - "Benson, Jack A."

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    Molecular and Neuronal Substrate for the Selective Attenuation of Anxiety by Löw, Karin, Crestani, Florence, Keist, Ruth, Benke, Dietmar, Brünig, Ina, Benson, Jack A., Fritschy, Jean-Marc, Rülicke, Thomas, Bluethmann, Horst, Möhler, Hanns, Rudolph, Uwe

    “…Benzodiazepine tranquilizers are used in the treatment of anxiety disorders. To identify the molecular and neuronal target mediating the anxiolytic action of…”
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    Benzodiazepine actions mediated by specific γ-aminobutyric acid A receptor subtypes by Rudolph, Uwe, Crestani, Florence, Benke, Dietmar, Brünig, Ina, Benson, Jack A, Fritschy, Jean-Marc, Martin, James R, Bluethmann, Horst, Möhler, Hanns

    Published in Nature (London) (21-10-1999)
    “…GABAA (γ-aminobutyric acidA) receptors are molecular substrates for the regulation of vigilance, anxiety, muscle tension, epileptogenic activity and memory…”
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    Stoichiometry of a recombinant GABAA receptor deduced from mutation-induced rectification by Backus, K H, Arigoni, M, Drescher, U, Scheurer, L, Malherbe, P, Möhler, H, Benson, J A

    Published in Neuroreport (01-12-1993)
    “…Ligand-gated ion channels generally display a heterooligomeric subunit structure. The present report describes an electrophysiological method that provides…”
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    Pharmacology of recombinant γ‐aminobutyric acidA receptors rendered diazepam‐insensitive by point‐mutated α‐subunits by Benson, Jack A, Löw, Karin, Keist, Ruth, Mohler, Hanns, Rudolph, Uwe

    Published in FEBS letters (24-07-1998)
    “…Amino acids in the α‐ and γ‐subunits contribute to the benzodiazepine binding site of GABAA‐receptors. We show that the mutation of a conserved histidine…”
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    Postsynaptic clustering of γ-aminobutyric acid type A receptors by the γ3 subunit in vivo by Kristin Baer, Christian Essrich, Jack A. Benson, Dietmar Benke, Horst Bluethmann, Jean-Marc Fritschy, Bernhard Lüscher

    “…Synaptic localization of γ-aminobutyric acid type A (GABA A ) receptors is a prerequisite for synaptic inhibitory function, but the mechanism by which…”
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    Electrophysiological pharmacology of the nicotinic and muscarinic cholinergic responses of isolated neuronal somata from locust thoracic ganglia by BENSON, J. A

    Published in Journal of experimental biology (01-09-1992)
    “…ABSTRACT Mechanically isolated neuronal somata from the thoracic ganglia of the locust Locusta migratoria remain electrophysiologically viable under current-or…”
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    Single‐channel properties of neuronal GABAA receptors from mice lacking the γ2 subunit by Lorez, Matthias, Benke, Dietmar, Lüscher, Bernhard, Möhler, Hanns, Benson, Jack A.

    Published in The Journal of physiology (15-08-2000)
    “…1 The aim of this study was to define the biophysical properties contributed by the γ2 subunit to native single GABAA receptors. 2 Single‐channel activity was…”
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    A novel GABA receptor in the heart of a primitive arthropod, Limulus polyphemus by BENSON, J. A

    Published in Journal of experimental biology (01-11-1989)
    “…ABSTRACT The isolated, intact heart of the marine arachnid Limulus polyphemus continues to beat in vitro for many hours. Application of γ-aminobutyric acid…”
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    Multiple serotonin-activated currents in isolated, neuronal somata from locust thoracic ganglia by BERMUDEZ, I, BEADLE, D. J, BENSON, J. A

    Published in Journal of experimental biology (01-04-1992)
    “…ABSTRACT Three different responses were evoked by pressure micro-application of serotonin onto freshly dissociated, current- and voltage-clamped neuronal…”
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    Excitatory effects of dopamine on the cardiac ganglia of the crabs Portunus sanguinolentus and Podophthalmus vigil by MILLER, M. W, BENSON, J. A, BERLIND, A

    Published in Journal of experimental biology (1984)
    “…1. Dopamine, a cardioexcitor in decapod crustaceans, increased the frequency and/or duration of bursts of action potentials in the semi-isolated cardiac…”
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    Burst reset and frequency control of the neuronal oscillators in the cardiac ganglion of the crab, Portunus sanguinolentus by Benson, J.A

    Published in Journal of experimental biology (01-08-1980)
    “…1. The five large and four small neurones in the cardiac ganglion of the crab, Portunus, are electrotonically coupled and behave as a single relaxation…”
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    Postsynaptic Clustering of γ -Aminobutyric Acid Type A Receptors by the γ 3 Subunit in vivo by Baer, Kristin, Essrich, Christian, Benson, Jack A., Benke, Dietmar, Bluethmann, Horst, Fritschy, Jean-Marc, Lüscher, Bernhard

    “…Synaptic localization of γ -aminobutyric acid type A (GABAA) receptors is a prerequisite for synaptic inhibitory function, but the mechanism by which different…”
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    Functional pharmacology of GABA A receptors containing the chicken brain γ4 subunit by Forster, Ian C., Harvey, Robert J., Darlison, Mark G., Benson, Jack A.

    Published in European journal of pharmacology (2001)
    “…The functional pharmacology of receptors composed of the chicken brain GABA A receptor γ4 subunit and the mammalian GABA A receptor α3 and β2 subunits was…”
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    Single-channel properties of neuronal GABA sub(A) receptors from mice lacking the gamma 2 subunit by Lorez, Matthias, Benke, Dietmar, Luescher, Bernhard, Mohler, Hanns, Benson, Jack A

    Published in The Journal of physiology (01-08-2000)
    “…* 1 The aim of this study was to define the biophysical properties contributed by the gamma 2 subunit to native single GABA sub(A) receptors. * 2…”
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  20. 20

    Electrophysiological pharmocology of the nicotinic and muscarinic cholinergic responses of isolated neuronal somata from locust thoracic ganglia by Benson, Jack A

    Published in Journal of experimental biology (01-09-1992)
    “…The pharmacology of the extrasynaptic nicotinic and muscarinic acetylcholine receptors of the isolated neuronal somata from locust thoracic ganglia and the…”
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