Search Results - "Benson, Jack A."
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Molecular and Neuronal Substrate for the Selective Attenuation of Anxiety
Published in Science (American Association for the Advancement of Science) (06-10-2000)“…Benzodiazepine tranquilizers are used in the treatment of anxiety disorders. To identify the molecular and neuronal target mediating the anxiolytic action of…”
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Postsynaptic clustering of major GABAA receptor subtypes requires the γ2 subunit and gephyrin
Published in Nature neuroscience (01-11-1998)Get full text
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Benzodiazepine actions mediated by specific γ-aminobutyric acid A receptor subtypes
Published in Nature (London) (21-10-1999)“…GABAA (γ-aminobutyric acidA) receptors are molecular substrates for the regulation of vigilance, anxiety, muscle tension, epileptogenic activity and memory…”
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Stoichiometry of a recombinant GABAA receptor deduced from mutation-induced rectification
Published in Neuroreport (01-12-1993)“…Ligand-gated ion channels generally display a heterooligomeric subunit structure. The present report describes an electrophysiological method that provides…”
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Pharmacology of recombinant γ‐aminobutyric acidA receptors rendered diazepam‐insensitive by point‐mutated α‐subunits
Published in FEBS letters (24-07-1998)“…Amino acids in the α‐ and γ‐subunits contribute to the benzodiazepine binding site of GABAA‐receptors. We show that the mutation of a conserved histidine…”
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Postsynaptic clustering of γ-aminobutyric acid type A receptors by the γ3 subunit in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (26-10-1999)“…Synaptic localization of γ-aminobutyric acid type A (GABA A ) receptors is a prerequisite for synaptic inhibitory function, but the mechanism by which…”
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Electrophysiological pharmacology of the nicotinic and muscarinic cholinergic responses of isolated neuronal somata from locust thoracic ganglia
Published in Journal of experimental biology (01-09-1992)“…ABSTRACT Mechanically isolated neuronal somata from the thoracic ganglia of the locust Locusta migratoria remain electrophysiologically viable under current-or…”
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Single‐channel properties of neuronal GABAA receptors from mice lacking the γ2 subunit
Published in The Journal of physiology (15-08-2000)“…1 The aim of this study was to define the biophysical properties contributed by the γ2 subunit to native single GABAA receptors. 2 Single‐channel activity was…”
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Functional pharmacology of GABAA receptors containing the chicken brain γ4 subunit
Published in European journal of pharmacology (04-05-2001)Get full text
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A novel GABA receptor in the heart of a primitive arthropod, Limulus polyphemus
Published in Journal of experimental biology (01-11-1989)“…ABSTRACT The isolated, intact heart of the marine arachnid Limulus polyphemus continues to beat in vitro for many hours. Application of γ-aminobutyric acid…”
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11
Multiple serotonin-activated currents in isolated, neuronal somata from locust thoracic ganglia
Published in Journal of experimental biology (01-04-1992)“…ABSTRACT Three different responses were evoked by pressure micro-application of serotonin onto freshly dissociated, current- and voltage-clamped neuronal…”
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Skiing at Camp Hale: Mountain Troops during World War II
Published in The Western historical quarterly (01-04-1984)Get full text
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Single‐channel properties of neuronal GABA A receptors from mice lacking the γ2 subunit
Published in The Journal of physiology (01-08-2000)Get full text
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Excitatory effects of dopamine on the cardiac ganglia of the crabs Portunus sanguinolentus and Podophthalmus vigil
Published in Journal of experimental biology (1984)“…1. Dopamine, a cardioexcitor in decapod crustaceans, increased the frequency and/or duration of bursts of action potentials in the semi-isolated cardiac…”
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Burst reset and frequency control of the neuronal oscillators in the cardiac ganglion of the crab, Portunus sanguinolentus
Published in Journal of experimental biology (01-08-1980)“…1. The five large and four small neurones in the cardiac ganglion of the crab, Portunus, are electrotonically coupled and behave as a single relaxation…”
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16
Before Skiing Was Fun
Published in The Western historical quarterly (01-10-1977)Get full text
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Postsynaptic Clustering of γ -Aminobutyric Acid Type A Receptors by the γ 3 Subunit in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (26-10-1999)“…Synaptic localization of γ -aminobutyric acid type A (GABAA) receptors is a prerequisite for synaptic inhibitory function, but the mechanism by which different…”
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18
Functional pharmacology of GABA A receptors containing the chicken brain γ4 subunit
Published in European journal of pharmacology (2001)“…The functional pharmacology of receptors composed of the chicken brain GABA A receptor γ4 subunit and the mammalian GABA A receptor α3 and β2 subunits was…”
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Single-channel properties of neuronal GABA sub(A) receptors from mice lacking the gamma 2 subunit
Published in The Journal of physiology (01-08-2000)“…* 1 The aim of this study was to define the biophysical properties contributed by the gamma 2 subunit to native single GABA sub(A) receptors. * 2…”
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20
Electrophysiological pharmocology of the nicotinic and muscarinic cholinergic responses of isolated neuronal somata from locust thoracic ganglia
Published in Journal of experimental biology (01-09-1992)“…The pharmacology of the extrasynaptic nicotinic and muscarinic acetylcholine receptors of the isolated neuronal somata from locust thoracic ganglia and the…”
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