Search Results - "Benson, Curtis A."

Dendritic Spines and Pain Memory by Benson, Curtis A., King, Jared F., Reimer, Marike L., Kauer, Sierra D., Waxman, Stephen G., Tan, Andrew M.

“…Neuropathic pain is a debilitating form of pain arising from injury or disease of the nervous system that affects millions of people worldwide. Despite its…”
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Conditional RAC1 knockout in motor neurons restores H-reflex rate-dependent depression after spinal cord injury by Benson, Curtis A., Olson, Kai-Lan, Patwa, Siraj, Reimer, Marike L., Bangalore, Lakshmi, Hill, Myriam, Waxman, Stephen G., Tan, Andrew M.

“…A major complication with spinal cord injury (SCI) is the development of spasticity, a clinical symptom of hyperexcitability within the spinal H-reflex…”
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Dendritic Spines in the Spinal Cord: Live Action Pain by Benson, Curtis A, Reimer, Marike L, Tan, Andrew M

“…Dendritic spines are microscopic protrusions on neurons that house the postsynaptic machinery necessary for neurotransmission between neurons. As such,…”
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Spinal cord motor neuron plasticity accompanies second‐degree burn injury and chronic pain by Patwa, Siraj, Benson, Curtis A., Dyer, Lauren, Olson, Kai‐Lan, Bangalore, Lakshmi, Hill, Myriam, Waxman, Stephen G., Tan, Andrew M.

“…Burn injuries and associated complications present a major public health challenge. Many burn patients develop clinically intractable complications, including…”
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Conditional Astrocyte Rac1KO Attenuates Hyperreflexia after Spinal Cord Injury by Benson, Curtis A, Olson, Kai-Lan, Patwa, Siraj, Kauer, Sierra D, King, Jared F, Waxman, Stephen G, Tan, Andrew M

“…Spasticity is a hyperexcitability disorder that adversely impacts functional recovery and rehabilitative efforts after spinal cord injury (SCI). The loss of…”
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Increased astrocytic GLT-1 expression in tripartite synapses is associated with SCI-induced hyperreflexia by Benson, Curtis A, King, Jared F, Kauer, Sierra D, Waxman, Stephen G, Tan, Andrew M

“…Spasticity is a chronic neurological complication associated with spinal cord injury (SCI), characterized by increased muscle tone and stiffness. A…”
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PAK1 inhibition with Romidepsin attenuates H‐reflex hyperexcitability after spinal cord injury by Kauer, Sierra D., Benson, Curtis A., Carrara, Jennifer M., Tarafder, Afrin A., Ibrahim, Youssef H., Estacion, Maile A., Waxman, Stephen G., Tan, Andrew M.

“…Hyperreflexia associated with spasticity is a prevalent neurological condition characterized by excessive and exaggerated reflex responses to stimuli…”
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Dendritic Spine Dynamics after Peripheral Nerve Injury: An Intravital Structural Study by Benson, Curtis A, Fenrich, Keith K, Olson, Kai-Lan, Patwa, Siraj, Bangalore, Lakshmi, Waxman, Stephen G, Tan, Andrew M

“…Neuropathic pain is an intractable medical condition with few or no options for effective treatment. Emerging evidence shows a strong structure-function…”
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Over-the-counter anti-oxidant therapies for use in multiple sclerosis: A systematic review by Plemel, Jason R., Juzwik, Camille A., Benson, Curtis A., Monks, Michael, Harris, Chelsea, Ploughman, Michelle

“…Background: Anti-oxidant compounds that are found in over-the-counter (OTC) supplements and foods are gaining interest as treatments for multiple sclerosis…”
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The MAO inhibitor phenelzine can improve functional outcomes in mice with established clinical signs in experimental autoimmune encephalomyelitis (EAE) by Benson, Curtis A., Wong, Grace, Tenorio, Gustavo, Baker, Glen B., Kerr, Bradley J.

“…•The MAO inhibitor PLZ improves clinical signs in established EAE.•PLZ elevates the levels of GABA, dopamine and biogenic amines in the CNS.•PLZ treatment…”
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A FAIR, open-source virtual reality platform for dendritic spine analysis by Reimer, Marike L., Kauer, Sierra D., Benson, Curtis A., King, Jared F., Patwa, Siraj, Feng, Sarah, Estacion, Maile A., Bangalore, Lakshmi, Waxman, Stephen G., Tan, Andrew M.

“…Neuroanatomy is fundamental to understanding the nervous system, particularly dendritic spines, which are vital for synaptic transmission and change in…”
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