Search Results - "Benschop, J J"

Gsk3 is a metabolic checkpoint regulator in B cells by Jellusova, Julia, Cato, Matthew H, Apgar, John R, Ramezani-Rad, Parham, Leung, Charlotte R, Chen, Cindi, Richardson, Adam D, Conner, Elaine M, Benschop, Robert J, Woodgett, James R, Rickert, Robert C

“…Mature B cells remain in a quiescent state until activated. Rickert and colleagues identify a prominent role for the kinase Gsk3 in resting naive B cells and…”
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Lithography for now and the future by van de Kerkhof, M.A., Benschop, J.P.H., Banine, V.Y.

“…•Amount of transistors on chip oubles every 1.5–2 years accordig to Moore’s law.•Multiple patterning is required to obtain ∼10–16 nm half-pitch using immersion…”
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Emerging Leptospira strain poses public health risk for dairy farmers in New Zealand by Yupiana, Y., Vallee, E., Wilson, P., Collins-Emerson, J., Weston, J., Benschop, J., Heuer, C.

“…Leptospira infection in dairy cattle and leptospirosis in dairy farm workers were common in New Zealand prior to the introduction of dairy cattle vaccination…”
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Two distinct repressive mechanisms for histone 3 lysine 4 methylation through promoting 3'-end antisense transcription by Margaritis, Thanasis, Oreal, Vincent, Brabers, Nathalie, Maestroni, Laetitia, Vitaliano-Prunier, Adeline, Benschop, Joris J, van Hooff, Sander, van Leenen, Dik, Dargemont, Catherine, Géli, Vincent, Holstege, Frank C P

“…Histone H3 di- and trimethylation on lysine 4 are major chromatin marks that correlate with active transcription. The influence of these modifications on…”
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Quantitative Phosphoproteomics of Early Elicitor Signaling in Arabidopsis by Benschop, Joris J., Mohammed, Shabaz, O'Flaherty, Martina, Heck, Albert J.R., Slijper, Monique, Menke, Frank L.H.

“…Perception of general elicitors by plant cells initiates signal transduction cascades that are regulated by protein phosphorylation. The earliest signaling…”
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Large-Scale Genetic Perturbations Reveal Regulatory Networks and an Abundance of Gene-Specific Repressors by Kemmeren, Patrick, Sameith, Katrin, van de Pasch, Loes A.L., Benschop, Joris J., Lenstra, Tineke L., Margaritis, Thanasis, O’Duibhir, Eoghan, Apweiler, Eva, van Wageningen, Sake, Ko, Cheuk W., van Heesch, Sebastiaan, Kashani, Mehdi M., Ampatziadis-Michailidis, Giannis, Brok, Mariel O., Brabers, Nathalie A.C.H., Miles, Anthony J., Bouwmeester, Diane, van Hooff, Sander R., van Bakel, Harm, Sluiters, Erik, Bakker, Linda V., Snel, Berend, Lijnzaad, Philip, van Leenen, Dik, Groot Koerkamp, Marian J.A., Holstege, Frank C.P.

“…To understand regulatory systems, it would be useful to uniformly determine how different components contribute to the expression of all other genes. We…”
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Immune Focusing and Enhanced Neutralization Induced by HIV-1 gp140 Chemical Cross-Linking by Schiffner, T, Kong, L, Duncan, C J A, Back, J W, Benschop, J J, Shen, X, Huang, P S, Stewart-Jones, G B, DeStefano, J, Seaman, M S, Tomaras, G D, Montefiori, D C, Schief, W R, Sattentau, Q J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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COVID-19 symptom relationship to antibody response and ACE2 neutralization in recovered health systems employees before and after mRNA BNT162b2 COVID-19 vaccine by Huhn, Gregory, Poorbaugh, Josh, Zhang, Lin, Beasley, Stephanie, Nirula, Ajay, Brothers, Jennifer, Welbel, Sharon, Wilson, James, Gillani, Sheena, Weber, Kathleen M, Morack, Ralph, Keckler, Kody, Benschop, Robert J

“…Background The humoral response to SARS-CoV-2 can provide immunity and prevent reinfection. However, less is known about how the diversity, magnitude, and…”
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From Structure to Systems: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II by Braberg, Hannes, Jin, Huiyan, Moehle, Erica A., Chan, Yujia A., Wang, Shuyi, Shales, Michael, Benschop, Joris J., Morris, John H., Qiu, Chenxi, Hu, Fuqu, Tang, Leung K., Fraser, James S., Holstege, Frank C.P., Hieter, Philip, Guthrie, Christine, Kaplan, Craig D., Krogan, Nevan J.

“…RNA polymerase II (RNAPII) lies at the core of dynamic control of gene expression. Using 53 RNAPII point mutants, we generated a point mutant epistatic…”
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Source attributed case-control study of campylobacteriosis in New Zealand by Lake, R.J., Campbell, D.M., Hathaway, S.C., Ashmore, E., Cressey, P.J., Horn, B.J., Pirikahu, S., Sherwood, J.M., Baker, M.G., Shoemack, P., Benschop, J., Marshall, J.C., Midwinter, A.C., Wilkinson, D.A., French, N.P.

“…•Reduction in human campylobacteriosis in New Zealand since 2008 has been relatively small.•A year-long source-attributed case-control study of notified human…”
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The Janus kinase 1/2 inhibitor baricitinib reduces biomarkers of joint destruction in moderate to severe rheumatoid arthritis by Thudium, Christian S, Bay-Jensen, Anne C, Cahya, Suntara, Dow, Ernst R, Karsdal, Morten A, Koch, Alisa E, Zhang, Wenling, Benschop, Robert J

“…Tissue released blood-based biomarkers can provide insight into drug mode of action and response. To understand the changes in extracellular matrix turnover,…”
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Campylobacteriosis associated with the consumption of unpasteurised milk: findings from a sentinel surveillance site by Davys, G, Marshall, J C, Fayaz, A, Weir, R P, Benschop, J

“…Campylobacteriosis is the most common notifiable disease in New Zealand. While the risk of campylobacteriosis has been found to be strongly associated with the…”
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Translational Pharmacodynamics of Calcitonin Gene-Related Peptide Monoclonal Antibody LY2951742 in a Capsaicin-Induced Dermal Blood Flow Model by Vermeersch, Steve, Benschop, Robert J, Van Hecken, Anne, Monteith, David, Wroblewski, Victor J, Grayzel, David, de Hoon, Jan, Collins, Emily C

“…LY2951742, a monoclonal antibody targeting calcitonin gene-related peptide (CGRP), is being developed for migraine prevention and osteoarthritis pain. To…”
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A humanized CD3ε-knock-in mouse model for pre-clinical testing of anti-human CD3 therapy by Crespo, Joel, Koh, Yi Ting, Hu, Ningjie, Moore, Paul A, Bonvini, Ezio, Glasebrook, Andrew L, Martin, Andrea P, Benschop, Robert J

“…Pre-clinical murine models are critical for translating drug candidates from the bench to the bedside. There is interest in better understanding how anti-human…”
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Cell cycle population effects in perturbation studies by O'Duibhir, Eoghan, Lijnzaad, Philip, Benschop, Joris J, Lenstra, Tineke L, van Leenen, Dik, Groot Koerkamp, Marian JA, Margaritis, Thanasis, Brok, Mariel O, Kemmeren, Patrick, Holstege, Frank CP

“…Growth condition perturbation or gene function disruption are commonly used strategies to study cellular systems. Although it is widely appreciated that such…”
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Strengthening ultrathin Si3N4 membranes by compressive surface stress by Shafikov, A., Schurink, B., van de Kruijs, R.W.E., Benschop, J., van den Beld, W.T.E., Houweling, Z.S., Bijkerk, F.

“…[Display omitted] •Fracture strength of Si3N4 thin film membranes is studied using bulge test.•Compressive surface stress is created by Ar-ion bombardment or…”
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Identification of Anergic B Cells within a Wild-Type Repertoire by Merrell, Kevin T., Benschop, Robert J., Gauld, Stephen B., Aviszus, Katja, Decote-Ricardo, Debora, Wysocki, Lawrence J., Cambier, John C.

“…The contribution of anergy to silencing of autoreactive B cells in physiologic settings is unknown. By comparing anergic and nonanergic…”
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The Specificity and Topology of Chromatin Interaction Pathways in Yeast by Lenstra, Tineke L., Benschop, Joris J., Kim, TaeSoo, Schulze, Julia M., Brabers, Nathalie A.C.H., Margaritis, Thanasis, van de Pasch, Loes A.L., van Heesch, Sebastiaan A.A.C., Brok, Mariel O., Groot Koerkamp, Marian J.A., Ko, Cheuk W., van Leenen, Dik, Sameith, Katrin, van Hooff, Sander R., Lijnzaad, Philip, Kemmeren, Patrick, Hentrich, Thomas, Kobor, Michael S., Buratowski, Stephen, Holstege, Frank C.P.

“…Packaging of DNA into chromatin has a profound impact on gene expression. To understand how changes in chromatin influence transcription, we analyzed 165…”
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Relationship between gene expression patterns from nasopharyngeal swabs and serum biomarkers in patients hospitalized with COVID-19, following treatment with the neutralizing monoclonal antibody bamlanivimab by Sims, Jonathan T, Poorbaugh, Josh, Chang, Ching-Yun, Holzer, Timothy R, Zhang, Lin, Engle, Sarah M, Beasley, Stephanie, Doman, Thompson N, Naughton, Lynn, Higgs, Richard E, Kallewaard, Nicole, Benschop, Robert J

“…A thorough understanding of a patient's inflammatory response to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is crucial to…”
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Comparison between generalized linear modelling and additive Bayesian network; identification of factors associated with the incidence of antibodies against Leptospira interrogans sv Pomona in meat workers in New Zealand by Pittavino, M., Dreyfus, A., Heuer, C., Benschop, J., Wilson, P., Collins-Emerson, J., Torgerson, P.R., Furrer, R.

“…Additive Bayesian Network (ABN) is a graphical model which extends Generalized Linear Modelling (GLM) to multiple dependent variables. The present study…”
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