Search Results - "Bensaude, Oliver"

An evolutionary conserved Hexim1 peptide binds to the Cdk9 catalytic site to inhibit P-TEFb by Kobbi, Lydia, Demey-Thomas, Emmanuelle, Braye, Floriane, Proux, Florence, Kolesnikova, Olga, Vinh, Joelle, Poterszman, Arnaud, Bensaude, Olivier

“…The positive transcription elongation factor (P-TEFb) is required for the transcription of most genes by RNA polymerase II. Hexim proteins associated with 7SK…”
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Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes by Busetto, Virginia, Barbosa, Isabelle, Basquin, Jérôme, Marquenet, Emélie, Hocq, Rémi, Hennion, Magali, Paternina, Janio Antonio, Namane, Abdelkader, Conti, Elena, Bensaude, Oliver, Le Hir, Hervé

“…Human CWC27 is an uncharacterized splicing factor and mutations in its gene are linked to retinal degeneration and other developmental defects. We identify the…”
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FRET Image Correlation Spectroscopy Reveals RNAPII-Independent P-TEFb Recruitment on Chromatin by Bidaux, Gabriel, Le Nézet, Corentin, Pisfil, Mariano Gonzalez, Henry, Mélanie, Furlan, Alessandro, Bensaude, Oliver, Vandenbunder, Bernard, Héliot, Laurent

“…Biochemical studies have revealed that the RNA Polymerase II (RNAPII) pause release is triggered by phosphorylation of the transcription machinery by the…”
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HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb by Furlan, Alessandro, Gonzalez-Pisfil, Mariano, Leray, Aymeric, Champelovier, Dorian, Henry, Mélanie, Le Nézet, Corentin, Bensaude, Oliver, Lefranc, Marc, Wohland, Thorsten, Vandenbunder, Bernard, Bidaux, Gabriel, Héliot, Laurent

“…How nuclear proteins diffuse and find their targets remains a key question in the transcription field. Dynamic proteins in the nucleus are classically…”
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7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor by Diribarne, Gaelle, Bensaude, Olivier

“…Human 7SK RNA is an abundant 331nt nuclear transcript generated by RNA polymerase III. Binding of 7SK RNA to HEXIM1/2 turns these proteins into inhibitors of…”
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Heat-induced Relocalization of Protein Kinase CK2 by Gerber, Delphine A., Souquere-Besse, Sylvie, Puvion, Fabienne, Dubois, Marie-Françoise, Bensaude, Oliver, Cochet, Claude

“…Among various other roles described so far, protein kinase CK2 has been involved in cell cycle, proliferation, and development. Here, we show that in response…”
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A heat shock-like protein from the human malaria parasite Plasmodium falciparum induces autoantibodies by Mattei, D, Scherf, A, Bensaude, O, da Silva, L P

“…The humoral immune response to a 72-kDa heat shock-like protein of Plasmodium falciparum has been analyzed using mouse monoclonal antibodies (mAb) and human…”
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LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated by Krueger, Brian J, Jeronimo, Célia, Roy, Bibhuti Bhusan, Bouchard, Annie, Barrandon, Charlotte, Byers, Sarah A, Searcey, Courtney E, Cooper, Jeffrey J, Bensaude, Olivier, Cohen, Éric A, Coulombe, Benoit, Price, David H

“…Regulation of the elongation phase of RNA polymerase II transcription by P-TEFb is a critical control point for gene expression. The activity of P-TEFb is…”
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Non-coding RNAs regulating the transcriptional machinery by Barrandon, Charlotte, Spiluttini, Béatrice, Bensaude, Olivier

“…During the past decade, numerous ncRNAs (non‐coding RNAs) have been identified as regulators of transcription. This review focuses on a few examples of ncRNAs…”
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The hyperfluidization of mammalian cell membranes acts as a signal to initiate the heat shock protein response by Balogh, Gábor, Horváth, Ibolya, Nagy, Enikõ, Hoyk, Zsófia, Benkõ, Sándor, Bensaude, Olivier, Vígh, László

“…The concentrations of two structurally distinct membrane fluidizers, the local anesthetic benzyl alcohol (BA) and heptanol (HE), were used at concentrations so…”
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Splicing-independent recruitment of U1 snRNP to a transcription unit in living cells by Spiluttini, Béatrice, Gu, Bo, Belagal, Praveen, Smirnova, Anna S, Nguyen, Van Trung, Hébert, Charles, Schmidt, Ute, Bertrand, Edouard, Darzacq, Xavier, Bensaude, Olivier

“…Numerous non-coding RNAs are known to be involved in the regulation of gene expression. In this work, we analyzed RNAs that co-immunoprecipitated with human…”
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Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex by Biglione, Sebastian, Byers, Sarah A, Price, Jason P, Nguyen, Van Trung, Bensaude, Olivier, Price, David H, Maury, Wendy

“…The positive transcription elongation factor, P-TEFb, comprised of cyclin dependent kinase 9 (Cdk9) and cyclin T1, T2 or K regulates the productive elongation…”
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Ubiquitination of HEXIM1 by HDM2 by Lau, Joanne, Lew, Qiao Jing, Diribarne, Gaelle, Michels, Annemieke A., Dey, Anwesha, Bensaude, Olivier, Lane, David P., Chao, Sheng-Hao

“…Hexamethylene bis-acetamide inducible protein 1 (HEXIM1) is an inhibitor of the  positive transcription elongation factor b (P-TEFb), which controls RNA…”
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Increased HEXIM1 expression during erythroleukemia and neuroblastoma cell differentiation by Turano, Mimmo, Napolitano, Giuliana, Dulac, Cyprien, Majello, Barbara, Bensaude, Olivier, Lania, Luigi

“…The HEXIM1 protein, in association with 7SK snRNA, binds and inhibits the kinase activity of P‐TEFb (CDK9/cyclin T). P‐TEFb activity is crucial for efficient…”
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Heat-induced relocalization of protein kinase CK2. Implication of CK2 in the context of cellular stress by Gerber, D A, Souquere-Besse, S, Puvion, F, Dubois, M F, Bensaude, O, Cochet, C

“…Among various other roles described so far, protein kinase CK2 has been involved in cell cycle, proliferation, and development. Here, we show that in response…”
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Nuclear translocation and carboxyl-terminal domain phosphorylation of RNA polymerase II delineate the two phases of zygotic gene activation in mammalian embryos by Bellier, Sylvain, Chastant, Sylvie, Adenot, Pierre, Vincent, Michel, Renard, Jean Paul, Bensaude, Olivier

“…In mammalian embryos, zygotic gene transcription initiates after a limited number of cell divisions through a two‐step process termed the zygotic gene…”
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The transcription-dependent dissociation of P-TEFb.HEXIM1.7SK RNA relies upon formation of hnRNP.7SK RNA complexes by Barrandon, C., Bonnet, Fabrice, Vt, Nguyen, Labas, Valérie, Bensaude, Oliver

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Unusual levels of heat shock element-binding activity in embryonal carcinoma cells by MEZGER, V, BENSAUDE, O, MORANGE, M

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Deficient activation of heat shock gene transcription in embryonal carcinoma cells by Mezger, Valérie, Bensaude, Olivier, Morange, Michael

“…Heat shock protein (HSP) synthesis cannot be induced by stress in the cleavage stage embryos of many different species. For instance, no HSP synthesis can be…”
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Regulation of the heat-shock response by interferon in mouse L cells by Dubois, M F, Mezger, V, Morange, M, Ferrieux, C, Lebon, P, Bensaude, O

“…Interferon (IFN) is not able to induce heat-shock protein (HSP) synthesis. However IFN pretreatment of mouse L cells has been shown to enhance the decrease of…”
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