Search Results - "Bensard, Claire L."
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HIF1A Employs CDK8-Mediator to Stimulate RNAPII Elongation in Response to Hypoxia
Published in Cell (06-06-2013)“…The transcription factor HIF1A is a key mediator of the cellular response to hypoxia. Despite the importance of HIF1A in homeostasis and various pathologies,…”
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2
Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis
Published in Cell metabolism (05-09-2017)“…Cold-induced thermogenesis is an energy-demanding process that protects endotherms against a reduction in ambient temperature. Using non-targeted liquid…”
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Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria
Published in eLife (17-08-2020)“…Cells harbor two systems for fatty acid synthesis, one in the cytoplasm (catalyzed by fatty acid synthase, FASN) and one in the mitochondria (mtFAS). In…”
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4
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis
Published in eLife (14-08-2020)“…Brown adipose tissue (BAT) is composed of thermogenic cells that convert chemical energy into heat to maintain a constant body temperature and counteract…”
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5
Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier
Published in Cell metabolism (04-02-2020)“…Although metabolic adaptations have been demonstrated to be essential for tumor cell proliferation, the metabolic underpinnings of tumor initiation are poorly…”
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6
ΔNp63α represses anti-proliferative genes via H2A.Z deposition
Published in Genes & development (15-10-2012)“…ΔNp63α is a member of the p53 family of transcription factors that functions as an oncogene in squamous cell carcinomas (SCCs). Because ΔNp63α and p53 bind…”
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7
HIF1A employs CDK8-Mediator to stimulate RNAPII elongation
Published in Cell (06-06-2013)“…The transcription factor HIF1A is a key mediator of the cellular response to hypoxia. Despite the importance of HIF1A in homeostasis and various pathologies,…”
Get full text
Journal Article